Neuroendocrine Carcinoma of Oral Cavity: A Case Report of an Unusual Presentation

Neuroendocrine carcinoma (NEC) are tumors affecting lungs in the first line. Extra-pulmonary locations are rare, and involvement of the oral cavity is uncommon. The therapeutic strategy of this clinically aggressive entity is not codified. Nevertheless, multimodal treatment combining surgery and radio-chemotherapy is associated with the best results in terms of local control and overall survival. We report a case of a 67-year-old patient, diagnosed with a NEC, the computed tomography (CT) of the facial mass objectified a jugal mass of 2x2.4 cm with two lymph nodes. The patient benefited from an excisional biopsy of the mass, and whose histological examination and immunohistochemical testing returned in favor of a small cell neuroendocrine carcinoma.

Sentinel lymph nodes biopsy in the surgical treatment of endometrial cancer: history and present

This article reviews the concept of sentinel lymph node biopsy in patients with endometrial cancer. This technique is becoming increasingly appreciated and was included into the latest standards of surgical treatment for gynecological cancers. Sentinel lymph node mapping is a reliable and highly specific (100 %) method, which can be used for determining the indications for adjuvant therapy in addition to a detailed pathomorphological examination that should include immunohistochemical testing and ultrastaging.