A REVIEW ON THE APPLICATION OF SOLID LIPID NANOPARTICLES IN TRANSDERMAL PATCH DRUG DELIVERY

The transdermal patches are used to deliver medication through the skin to treat the entire ailment. These depend on a unique size property of skins to encoded drugs solid lipid nanoparticles (SLNs) current a chance to create upon novel therapeutic properties used for drugs transmission SLN targeting holds great potential for target achieving, a penalty area, Many aspects of the loaded of SLN sin transdermal patches for increasing mechanism of penetration, formulation, characterization parameters, future advantages, limitations of SLNs, had better biocompatibility, low harmfulness, SLNs is physically stable, and better delivery for Lipophilic drugs are discussed here. SLNs are a hybrid of liposomes and polymer-based carriers that could be used to encapsulate both lipid and water-soluble medicines. SLN is a low-cost product that can be scaled up. They also have a long-life span and could be customized by using different lipids. Because of their multiple significant qualities, SLNs also started to emerge when effective drug delivery carriers, as well as the prospect with liposome delivery of drugs, depends heavily on them. Many patents relating to SLNs have already been submitted, there are more invented SLN-based delivery systems on the way soon.

Sequential decreasing strong size properties

Let X be a continuum. The n-fold hyperspace Cn(X), n < ∞, is the space of all nonempty closed subsets of X with at most n components. A topological property $ \mathcal{P} $ is said to be a (an almost) sequential decreasing strong size property provided that if μ is a strong size map for Cn(X, $ \{t_{j}\}_{j=1}^{\infty} $ is a sequence in the interval (t,1) such that lim tj = t ∈ [0,1) (t ∈ (0,1)) and each fiber μ−1(tj) has property $ \mathcal{P} $, then so does μ−1(t). In this paper we show that the following properties are sequential decreasing strong size properties: being a Kelley continuum, local connectedness, continuum chainability and, unicoherence. Also we prove that indecomposability is an almost sequential decreasing strong size property.

Application of Ecological Size in Term of Textile Process

Discussion on application on ecological size on warp sizing in textile production, aimed to substitute PVA(Polyvinyl alcohol) as primary size in warp slashing, which has been used for a long term despite of poor degradation in nature. Concerning the ecological sizing, the key factors such as size property, sizing recipe as well as technique parameters known as sizing regain, moisture regain, elongation regain, squeezing pressure, viscosity of size glue, solid content and other factors has been discussed.