Pericardial Disease and Cardiac Tumors

The space between the visceral and parietal pericardium normally contains 15 to 25 mL of clear fluid. The pericardium functions to prevent cardiac distention, limit cardiac displacement (by its attachment to neighboring structures), and protect the heart from inflammation. The chest pain of pericarditis is aggravated by movement of the trunk, inspiration, and coughing. The pain can be relieved by sitting up. Low-grade fever and malaise may occur.