Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
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Published By Springer US

9781475715224, 9781475715200

Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

Utility of Kinetic, Dynamic, and Metabolic Data in Nonclinical Pharmacology/Toxicology Studies

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_3 ◽

1993 ◽

pp. 15-22

Author(s):

Judi Weissinger

Keyword(s):

Metabolic Data

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Concentration-Controlled Trials: Basic Concepts, Design, and Implementation

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_25 ◽

1993 ◽

pp. 239-247

Author(s):

Lilly P. Sanathanan ◽

Carl C. Peck

Keyword(s):

Controlled Trials ◽

Design And Implementation ◽

Basic Concepts

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The Benzodiazepines: Kinetic-Dynamic Relationships

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_23 ◽

1993 ◽

pp. 217-223

Author(s):

David J. Greenblatt

Keyword(s):

Dynamic Relationships

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Assessment of Pharmacokinetic Drug Interactions in Clinical Drug Development

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_17 ◽

1993 ◽

pp. 149-157

Author(s):

Jerome J. Schentag

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Clinical Drug Development ◽

Clinical Drug ◽

Pharmacokinetic Drug

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Preclinical Pharmacodynamics of Antihypertensives

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_10 ◽

1993 ◽

pp. 81-89

Author(s):

Robert A. Branch ◽

Edwin K. Jackson

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Pharmacokinetics and Drug Metabolism in Animal Studies (ADME, Protein Binding, Mass Balance, Animal Models)

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_4 ◽

1993 ◽

pp. 23-31 ◽

Cited By ~ 1

Author(s):

Glenna G Fitzgerald

Keyword(s):

Animal Models ◽

Drug Metabolism ◽

Protein Binding ◽

Mass Balance ◽

Animal Studies ◽

Pharmacokinetics And Drug Metabolism

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Pharmacodynamic/Pharmacokinetic Relationships for Rapidly Acting Drugs (NSAIDS) in Rheumatoid Arthritis: Problems and Preliminary Solutions

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_20 ◽

1993 ◽

pp. 193-200 ◽

Cited By ~ 1

Author(s):

Daniel E. Furst

Keyword(s):

Rheumatoid Arthritis

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Use of Toxicokinetic Principles in Drug Development: Bridging Preclinical and Clinical Studies

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_8 ◽

1993 ◽

pp. 55-67

Author(s):

Mauricio Leal ◽

Avraham Yacobi ◽

Vijay K. Batra

Keyword(s):

Drug Development ◽

Clinical Studies ◽

Preclinical And Clinical Studies

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Use of Pharmacokinetics and Pharmacodynamics in Preclinical Studies to Guide Dosage Escalation Schemes in Phase I Studies of Anticancer Drugs

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_7 ◽

1993 ◽

pp. 49-53

Author(s):

Jerry M. Collins

Keyword(s):

Phase I ◽

Anticancer Drugs ◽

Preclinical Studies ◽

Pharmacokinetics And Pharmacodynamics ◽

Phase I Studies ◽

Dosage Escalation

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Use of Acute Toxicity Data in the Design and Interpretation of Subchronic and Chronic Toxicity Studies

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development ◽

10.1007/978-1-4757-1520-0_6 ◽

1993 ◽

pp. 39-48

Author(s):

Karl K. Rozman

Keyword(s):

Acute Toxicity ◽

Chronic Toxicity ◽

Toxicity Data ◽

Toxicity Studies

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Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug DevelopmentLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer US

Utility of Kinetic, Dynamic, and Metabolic Data in Nonclinical Pharmacology/Toxicology Studies

Concentration-Controlled Trials: Basic Concepts, Design, and Implementation

The Benzodiazepines: Kinetic-Dynamic Relationships

Assessment of Pharmacokinetic Drug Interactions in Clinical Drug Development

Preclinical Pharmacodynamics of Antihypertensives

Pharmacokinetics and Drug Metabolism in Animal Studies (ADME, Protein Binding, Mass Balance, Animal Models)

Pharmacodynamic/Pharmacokinetic Relationships for Rapidly Acting Drugs (NSAIDS) in Rheumatoid Arthritis: Problems and Preliminary Solutions

Use of Toxicokinetic Principles in Drug Development: Bridging Preclinical and Clinical Studies

Use of Pharmacokinetics and Pharmacodynamics in Preclinical Studies to Guide Dosage Escalation Schemes in Phase I Studies of Anticancer Drugs

Use of Acute Toxicity Data in the Design and Interpretation of Subchronic and Chronic Toxicity Studies

Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
Latest Publications