Modulation of Matrix Metalloproteinases in Sjogren's Syndrome by Proinflammatory Cytokines

Key words: Sjogren's syndrome; Matrixmetalloproteinases (MMPS);Proinflammatory cytokinesDOI: 10.3329/bjpath.v24i2.4113Bangladesh J Pathol 24(2): 15-20

Uncommon pancreatic tumor - a case report

Keywords: uncommon pancreatic cancer; anaplastic carcinomaDOI: http://dx.doi.org/10.3329/bjpath.v26i1.9151 BJPATH 2011; 26(1): 39-40

Gaucher's Disease - A Case of Huge Hepatosplenomegaly Clinically Confused with Kala Azar: Case Report and Review of the Literature

Key words: Hepatosplenomegaly; kala azar; Gaucher's diseaseDOI: 10.3329/bjpath.v24i2.4115Bangladesh J Pathol 24(2): 25-33

Swine Flu Pandemic: Bangladesh Perspective

DOI: 10.3329/bjpath.v24i2.4109Bangladesh J Pathol 24(2): 1-3

Comparative Study of Imprint Cytology and Frozen Section in the Intraoperative Diagnosis of Thyroid Lesions

Imprint cytology can provide a useful adjunct to the frozen section diagnosis and may be used safely in the intraoperative diagnosis of thyroid nodules, especially in the centres where frozen section facilities are not available. This study was conducted to compare imprint cytology and frozen section in terms of diagnostic accuracy, sensitivity, specificity, positive predictive value and to assess the value of imprint cytology in the intraoperative diagnosis of thyroid lesions. A total of 57 consecutive patients were enrolled in the study. All of the patients underwent frozen section in the department of pathology, BSMMU, Dhaka. Imprints were taken from the fresh specimen sent for frozen section from departments of otolaryngology and surgery of BSMMU. Imprint slides were stained with rapid H & E staining method. Then the tissues were submitted for frozen section by standard method. In this study, diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value of imprint cytology were 81.25%, 66.66%, 82.59%, 87.12% respectively. Frozen section revealed the diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive as 88.46%, 72.72%, 100%, 100%, 83.33% respectively. Imprint cytology was found to be comparable with frozen section in diagnostic accuracy and sensitivity. Since imprint cytology is a simple and cost-effective procedure it can be used as an alternative to frozen section in hospitals where frozen section facilities are not available. Key Words: Imprint cytology, frozen section, intraoperative diagnosis of thyroid lesions doi: 10.3329/bjpath.v24i1.2876 Bangladesh J Pathol 24 (1) : 12-15

Human Papilloma Virus in Cervical Cancer Carcinogenesis and Its Immunology

DOI: http://dx.doi.org/10.3329/bjpath.v26i1.9125BJPATH 2011; 26(1): 1-2

Value of discrimination indices in screening of beta thalassaemia trait

Key words: Beta thalassaemia; discrimination indicesDOI: 10.3329/bjpath.v25i1.4126Bangladesh J Pathol 25(1): 14-17

Myelodysplastic Syndrome with Tuberculosis which Developed to AML - A Case Report

A 60 year old male presented with pulmonary tuberculosis and moderate anaemia. He was on antitubercular treatment and haematinics. The anaemia remained refractory to treatment. But the patient developed recurrent deep vein thrombosis and pancytopenia, which subsequently transformed into acute myeloid leukemia (AML).The development of AML suggested that the haematological aberrations observed earlier were actually states of myelodysplastic syndrome (MDS). The significance of concurrently developing AML and MDS is discussed and reported here. doi: 10.3329/bjpath.v24i1.2879 Bangladesh J Pathol 24 (1) : 25-27

Histopathological diagnosis of surgical speciments in a Tertiary Hospital in Dhaka

Key words: Surgically resected specimen; histopathological diagnosis and its importanceDOI: 10.3329/bjpath.v24i2.4111Bangladesh J Pathol 24(2): 8-10

A single pathological grading system for breast carcinoma should be adopted in Bangladesh

DOI: 10.3329/bjpath.v24i2.4112Bangladesh J Pathol 24(2): 11-14