scholarly journals Histopathological diagnosis of surgical speciments in a Tertiary Hospital in Dhaka

1970 ◽  
Vol 24 (2) ◽  
pp. 8-10
Author(s):  
Md Tahminur Rahman ◽  
Sonia Shirin ◽  
Tanjila Tahmin Sarnali ◽  
Mahbuba Ashrafi Mumu

Key words: Surgically resected specimen; histopathological diagnosis and its importanceDOI: 10.3329/bjpath.v24i2.4111Bangladesh J Pathol 24(2): 8-10

Author(s):  
Aastha Raheja ◽  
Krishna Agarwal ◽  
Anoosha K. Ravi

Background: Cervical cancer is a disease which claims maximum number of deaths in developing countries. Objective of this study was to understand the reason for delayed approach to medical help in women with advanced carcinoma cervix.Methods: It was a cross-sectional study. Information obtained from women with carcinoma cervix clinical stage IIb and above with proven histopathological diagnosis was recorded in the predetermined format.Results: Almost all the subjects were illiterate and were from lower socioeconomic strata and rural areas. None of them knew about the disease and its symptomatology. About 82% of the patients were symptomatic since 5-10 years however took no medical care during the period and 2/3rd of them even did not reveal their problem to any of the family members. About 79% of the subjects had never used any contraception and none had knowledge about its role in preventing infection. Majority of them (98%) had no idea about the role of PAP smear in screening carcinoma cervix. All of them said if they had knowledge about the disease, they would have sought medical help much earlier.Conclusions: The most important reason for delayed approach in our study was found to be lack of knowledge about the disease. Therefore, till such time that we have national screening program in place, these women who are at high risk of developing carcinoma of cervix should be targeted and educated through mass media so that these women could seek medical help in early stages.


2019 ◽  
Vol 17 (2) ◽  
pp. 62-65
Author(s):  
Ram Sagar Shah ◽  
Dipesh Raj Pandey

Background: Prostatic Specific Antigen (PSA) is a protease secreted by epithelial cells of prostate. Serum PSA level is increased when the normal structure of gland is destroyed by benign or malignant tumor or inflammation. Though there is established relation between PSA plasma level and age among the two most common prostate diseases (Benign prostatic hyperplasia and Carcinoma Prostate) in the literature, relation has not been explored in our part of the world, therefore, this study was done to see the relation between age and PSA amount with Prostate diseases. Material and Methods: This was a Cross-sectional study conducted in a tertiary hospital, Nobel Medical College Teaching Hospital from January 2017 to December 2018. Ethical clearance was obtained from Institutional Review Committee (IRC). All the cases of prostate diseases presenting to urology department undergoing transurethral resection of the prostate (TURP) were included. Histopathology report of TURP specimen were collected from department of pathology and the relationship between diagnosis, PSA level and age were established. Results: BPH was the most common diagnosis (72.41%). Age of BPH patients ranged from 48-78 years and mean age with SD was 60.56±7.32. Median age with interquartile range was 61.00. Similarly, in the BPH group, PSA value ranged between 0.80-15.40 ng/ml with mean PSA value along with SD being 5.64±4.16 ng/ml. Similarly, Median PSA value with interquartile range was 4.20ng/ml. Carcinoma Prostate (27.59%) was the second most common diagnosis. Histological type of all cases diagnosed as cancer was adenocarcinoma. Their age ranged between 54-83. Their mean age with SD was 67.67±7.68. Similarly, Median age with interquartile range was 68.00. PSA value in this group ranged between 8.50-147.30 ng/ml. Again, the mean PSA value with SD is 55.72±33.40 ng/ml. Similarly, Median PSA value with interquartile range is 54.30 ng/ml. Conclusion: PSA level in the blood of men over 40years is highly correlated with a Age, irrespective of diagnosis. In above 40 age group, with advancing age, Carcinoma Prostate becomes more and more common diagnosis than BPH. Similarly, average PSA level is higher in Carcinoma Prostate than BPH.


2021 ◽  
Vol 9 (2.3) ◽  
pp. 8012-8019
Author(s):  
THIAM Sokhna Astou ◽  
◽  
MAR Ndeye Bigué ◽  
YACOUBA GARBA Karim ◽  
SECK Issa Dior ◽  
...  

Bronchial distribution in the upper lobe of the right lung is subject to many anatomical variations. The control of these variations is essential for the interpretation of endoscopic examinations. It also offers a better guarantee for safe surgery during segmentations in the right upper lobe. In this preliminary work, the operation of 30 heart-lung blocks treated by the injection-corrosion method, 100 CT chest and dissections of 3 resected specimen of right upper lobectomy, allowed us to study the bronchial distribution in the upper lobe of the right lung as well as their anatomical variations in melanoderm subjects. Our results were as follows: out of the 133 specimens, the right upper lobar bronchus was born on average 1.8 cm from the tracheal bifurcation, with an average length of 1.75 cm. There were 6 termination modes, dominated by bifurcations, which involved 52% of the specimens, and in 5 modes. Trifurcation accounted for 47.37% of cases. There was a case of quadrifurcation. These results allowed us to discuss anatomical variations of the bronchial shaft of the upper lobe of the right lung. Taking into account these variations will allow to avoid pitfalls and accidents during endoscopic examinations, medical imaging and pulmonary exeresis. KEY WORDS: Bronchi-Right Upper Lobe-Anatomy-Variations- Endoscopy-Imaging-Surgery.


2020 ◽  
Vol 54 (1) ◽  
pp. 36-41
Author(s):  
Uchenna C. Okechi ◽  
James O. Akpeh ◽  
Felix N. Chukwuneke ◽  
Birch D. Saheeb ◽  
Chukwubuzor U. Okwuosa ◽  
...  

Background: Ameloblastoma is one of the most common benign odontogenic tumours in Nigeria. It is considered uncommon in children. Materials and methods: This is a retrospective study of pediatric patients with histopathological diagnosis of ameloblastoma seen over seven years at the Oral and Maxillofacial Surgery Department of the University of Nigeria Teaching Hospital, Enugu, Nigeria. Relevant information was retrieved from patients’ records and data obtained were analysed using SPSS version 23, the chi-square test was used to compare qualitative variables, a p-value of <0.05 was considered as significant. Results: One hundred and thirty-six cases of ameloblastoma in all age groups were seen within the period. Thirty of the cases met the requirement. The mean age of the patients was 14.4 STD 2.03 (range from 10-17) years. Fourteen (46.7%) patients were male while 16 (53.3%) were female giving a ratio of 1:1.1. The duration of the lesion ranged from 3 months to 72 months (mean 15.07 months). Histologically, the follicular type (n=20, 66.7%) constitute the majority, while the clinical types were solid-multicystic (n=18, 60%) and unicystic (n=12, 40%). Enucleation was the treatment of choice in most (n=18, (60%)) of the patients. Conclusion: Ameloblastoma is relatively uncommon in children, especially those less than ten years of age. The solidmulticystic variety was the predominant type in the children studied. Most patients presented long after the onset of the tumour and enucleation with mechanical curettage produced satisfactory results in these patients. Keywords: Ameloblastoma, odontogenic tumour, children, resection, enucleation. Funding: None declared


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S72-S72
Author(s):  
Evans Aboagye ◽  
Emmanuel Asante ◽  
Felicia Owusu-Afriyie ◽  
Nicholas Titiloye ◽  
Babatunde Duduyemi

Abstract Objectives Prostate adenocarcinoma (PCa) accounts for considerable morbidity in aging men in Africa. With fewer studies reporting on PCa within the subregion, this study was set out to analyze various clinicopathological patterns in PCa lesions, providing additional data for comparison with reported PCa cases in other parts of the globe. Methods The study included prostatic adenocarcinoma tissues received in the Department of Pathology, Komfo Anokye Teaching Hospital, over a period of 6 years (from 2008 to 2013). Relevant clinical data including age, histopathological diagnosis, and Gleason’s microscopic grading were extracted from the surgical day book of the department. In a consecutive order, archived tissue blocks and slides of the selected cases were also retrieved for review and confirmation of diagnosis. Results Mean age at presentation was 71.7 ± 8.72 years (age ranged from 53 to 96 years) with a peak in the seventh decade of life (n = 41, 52.6%). Majority of the cases were poorly differentiated (n = 43, 55.1%), followed by moderately differentiated (n = 20, 25.6%) and well-differentiated samples (n = 15, 19.2%). Highest occurrence of prostate adenocarcinoma was recorded in the year 2009 (n = 46), followed by 2008 and 2009 (n = 16 and 13, respectively), together accounting for 96.2% of the cases reported. Conclusion Histopathological evaluation of prostatic biopsies remains the mainstay of diagnosing prostate adenocarcinoma in Ghana. The pattern of incidence in the population is in line with several reported studies, with majority of the cases diagnosed at the late stage of the disease and thus portending worse prognosis.


Author(s):  
Kalpana Betha ◽  
Lavanya Malavatu ◽  
Sreeveena Talasani

Background: Abnormal Uterine Bleeding (AUB) is a significant debilitating clinical condition. It may have a significant impact on women’s quality of life with significant burden to the country’s economy. The primary aim was to categorize women with Abnormal Uterine Bleeding (AUB) according to PALM COEIN classification system and to correlate the clinical diagnosis and histopathologic features of various causes of AUB.Methods: A retrospective study was carried out on 250 non-gravid reproductive age women between 25-45 years with complaints of AUB at Mediciti Institute of Medical Sciences, a rural tertiary teaching hospital during the period January 2014 to December 2015.Results: The PALM and COEIN groups accounted for 60.4% and 39.6% respectively. Leiomyoma was the most common cause of AUB (30.4%) and Ovulatory disorders was the 2nd most common cause of AUB (13.6%). A total of 172 (68.8%) were classified as having chronic AUB and 78(31.2%) as having acute AUB. In AUB-L, the difference in clinical and histopathological diagnosis was significant (p=0.03).Conclusions: Structural causes of AUB contributed more to the cause of AUB. The PALM COEIN classification system helps us in understanding various etiological causes of AUB and can be used by clinicians and researchers for international comparisons. 


Author(s):  
Sheen Maria James ◽  
Robert P. Ambooken ◽  
Rahul Raj K. ◽  
Vipin Krishnan ◽  
Manu Joseph

Background: Endometrial carcinoma is the fourth most common cancer in females and the most common malignancy of the female reproductive tract. The prognosis of endometrial carcinoma depends on a number of factors, including stage, depth of myometrial invasion, lympho-vascular invasion, nodal status and histologic grade. Preoperative assessment with MRI is essential for planning surgery and lymph node sampling. The objectives of this study were to determine the myometrial invasion of endometrial carcinoma by MRI and to obtain histopathology in surgically resected specimen, to compare the MRI findings of myometrial invasion in endometrial carcinoma with histopathology in respectable cases.Methods: Authors analyzed 41 cases in whom, histopathological diagnosis of carcinoma endometrium was established by means of pre-treatment biopsy. Consenting patients were taken up for preoperative MRI FIGO staging. MR images were reviewed for parameters like depth of myometrial invasion. Further surgical management followed by histopathological FIGO staging was done.Results: The study showed MRI was highly sensitive and specific tool for identifying depth of myometrial invasion, cervical invasion, serosal invasion, vaginal and parametrial invasion.Conclusions: There was statistically significant difference between histopathological and MRI assessment of local invasion of endometrial carcinoma.


2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Anuradha Sinha ◽  
Jyoti Prakash Phukan ◽  
Sanjay Sengupta ◽  
Paulami Guha

Background. Mullerian adenosarcoma with sarcomatous overgrowth (MASO) is a very rare variant of uterine sarcomas first described by Clement et al. as early as 1974. The presence of heterologous sarcomatous components is associated with aggressive biological behavior.Case Presentation. This is a case report of a 62-year female (P2 + 0) presenting with postmenopausal vaginal bleeding. Her preoperative USG revealed subserosal fibroid with adherent omentum. She underwent abdominal hysterectomy with bilateral oophorectomy. Histopathological diagnosis of resected specimen was Mullerian adenosarcoma with sarcomatous overgrowth and presence of heterologous elements involving body of the uterus. The whole thickness of the myometrium was involved along with the presence of serosal nodules and omental deposits of sarcomatous component.Conclusion. MA is considered as a low-grade malignant tumor, but MASO is a high-grade tumor frequently associated with invasion and metastasis with poor treatment outcome. Because of its rarity, correct identification of these tumors and distinction from other uterine sarcomas are a challenging job and hence its morphological features merits attention.


1970 ◽  
Vol 21 (1) ◽  
pp. 34-39
Author(s):  
Mohammad Rafiqul Mowla ◽  
Mansurul Alam ◽  
Md Gofranul Hoque ◽  
AQM Serajul Islam ◽  
Nishit Ranjan Dey ◽  
...  

Key words: SLE; cutaneous; ChittagongDOI: 10.3329/jcmcta.v21i1.7668 Journal of Chittagong Medical College Teachers' Association 2010: 21(1):34-39


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