Natural history of sensitizations in atopic dermatitis. A 3-year follow-up in 250 children: food allergy and high risk of respiratory symptoms

ABSTRACT:Studies which have attempted to define the outcome of multiple sclerosis (MS) have methodologic difficulties arising from patient referral biases and the length of follow-up required, which make prospective studies of an inception cohort unrealistic. Means to improve the validity of retrospective natural history studies are suggested. Results of existing series are summarized and compared. Survival is only rarely shortened by MS, but disability to the point of requiring aids for ambulation occurs in 30-70% of patients by 15 years from onset of symptoms. Disagreement as to the percentage of patients who are ultimately bedridden by MS likely arises in large part due to differences in patient ascertainment and follow-up. The need to develop early clinical markers for the patient at high risk for rapid development of major disability is stressed.

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Natural history of egg allergy in a large cohort of infants with food allergy shows its high prevalence but also its transient nature in a 36 months of follow -up

10.26226/morressier.5acc8ad4d462b8028d89b781 ◽

2018 ◽

Author(s):

Andrea Polouckova

Keyword(s):

Food Allergy ◽

Natural History ◽

Large Cohort ◽

Egg Allergy ◽

Transient Nature ◽

High Prevalence ◽

History Of

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Natural history of atopic dermatitis in childhood: an updated review and personal experience of a five-year follow-up

Allergy ◽

10.1111/j.1398-9995.1989.tb02459.x ◽

1989 ◽

Vol 44 (s9) ◽

pp. 70-78 ◽

Cited By ~ 20

Author(s):

Luisa Businco ◽

Maria G. Ziruolo ◽

Matteo Ferrara ◽

Nicolletta Benincori ◽

Atonella Muraro ◽

...

Keyword(s):

Atopic Dermatitis ◽

Natural History ◽

Personal Experience ◽

History Of

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The Natural History of Sensitizations to Food and Aeroallergens in Atopic Dermatitis: A 4‐Year Follow‐Up

Pediatric Dermatology ◽

10.1046/j.1525-1470.2000.01771.x ◽

2000 ◽

Vol 17 (4) ◽

pp. 261-265 ◽

Cited By ~ 23

Author(s):

Annalisa Patrizi ◽

Valentina Guerrini ◽

Giampaolo Ricci ◽

Iria Neri ◽

Fernando Specchia ◽

...

Keyword(s):

Atopic Dermatitis ◽

Natural History ◽

History Of

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Use of antithrombotic agents in patients with intracerebral cavernous malformations

Journal of Neurosurgery ◽

10.3171/2012.8.jns112050 ◽

2013 ◽

Vol 118 (1) ◽

pp. 43-46 ◽

Cited By ~ 16

Author(s):

Kelly D. Flemming ◽

Michael J. Link ◽

Teresa J. H. Christianson ◽

Robert D. Brown

Keyword(s):

High Risk ◽

Natural History ◽

Antiplatelet Agent ◽

Antithrombotic Agents ◽

Antithrombotic Agent ◽

Cavernous Malformations ◽

Risks And Benefits ◽

History Of ◽

The Mean

Object The goal of this study was to determine the risk of using antithrombotic agents in patients with established intracerebral cavernous malformations (ICMs). Methods From a previously described cohort of 292 patients with radiographically defined ICMs, 40 required an antithrombotic after the ICM was diagnosed. Patients underwent follow-up to determine the incidence of hemorrhage. Results The mean age of these 40 patients was 62.4 years; there were 21 male and 19 female patients. Five (12.5%) of the 40 patients initially presented with hemorrhage and 4 (10%) had multiple ICMs. Of these patients, 32 were placed on an antiplatelet agent alone, 6 on an anticoagulant alone, and 2 were placed on both. In patients necessitating any antithrombotic agent, 1 patient developed a prospective hemorrhage over the 258 person-years of follow-up (prospective hemorrhage rate 0.41% per person-year). Conclusions Antithrombotics likely do not precipitate hemorrhage in patients with known ICMs. However, caution should be exercised in the use of antithrombotics in patients with ICMs at high risk for hemorrhage. The risks and benefits of antithrombotics in each situation should be carefully weighed against the natural history of ICM.

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Case Study on Post-Discharge Persistence or Reappearance of Respiratory Symptoms in COVID-19 Hypoxia Patients

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i37a31976 ◽

2021 ◽

pp. 31-39

Author(s):

Jayshree Kharche ◽

Deepak S. Khismatrao ◽

Reshma Patil ◽

Rajkumar Nikalje

Keyword(s):

Natural History ◽

Observational Study ◽

Study Design ◽

Respiratory Symptoms ◽

Oxygen Therapy ◽

Post Discharge ◽

Respiratory Problems ◽

History Of

Introduction: News published about persistence or reappearance of symptoms in Covid 19 is worrisome. However, only one study from Italy is observed in this reference. Aim: the current study is conducted to study persistence or reappearance of especially respiratory symptoms amongst COVID 19 hypoxia patients. Study Design: Post-discharge follow-up, observational study with the telephonic interview of Covid 19 hypoxia patients from a dedicated Covid 19 hospital in India. Methods: Sixty-two patients were interviewed 1 – 3 months post-discharge to elicit history on persistence or reappearance of respiratory symptoms. Results: out of the results many patients doesnot show any symptoms compared to female, male are more prone to respiratory problems. Thus, the oxygen therapy showed proof that males are more prone to illness and depict the symptoms compared to females. Conclusion: A large multi-centric year-long study is recommended to further conclude on the natural history of the disease.

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