scholarly journals Detection of Cortical Inflammatory Lesions by Double Inversion Recovery Magnetic Resonance Imaging in Patients With Multiple Sclerosis

2007 ◽  
Vol 64 (10) ◽  
pp. 1416 ◽  
Author(s):  
Massimiliano Calabrese ◽  
Nicola De Stefano ◽  
Matteo Atzori ◽  
Valentina Bernardi ◽  
Irene Mattisi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Inversion Recovery ◽  
Double Inversion Recovery ◽  
Resonance Imaging ◽  
Inflammatory Lesions

scholarly journals Magnetic Resonance Imaging (MRI) Double Inversion Recovery Sequence in Diagnosis of Multiple Sclerosis

2021 ◽  
pp. 47-55
Author(s):  
Ahmed Samir Ghonim ◽  
Rasha Lotfy Younes ◽  
Mohamed Amin Mohamed ◽  
Mohamed Fathy Dawoud
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
White Matter ◽  
Magnetic Resonance ◽  
Inversion Recovery ◽  
University Hospital ◽  
Double Inversion Recovery ◽  
P Value ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Aims: The current work aimed to assess the diagnostically value of Magnetic Resonance Imaging (MRI) Double Inversion Recovery (DIR) sequence in diagnosing of multiple sclerosis. Methodology: This study conducted on (42 patients) from the Diagnostic Radiology and Medical Imaging Dep. at Tanta University Hospital in the period from March 2018 to December 2019. Results: In accordance to the total lesions loads, it was found that DIR was higher significantly than T2WI (P-value= 0.003 with a relative gaining of 22%), we found that double inversion recovery (DIR) sequence was higher significantly to FLAIR regarding the number of diagnosed lesions in 3 anatomical areas (Mixed W-GM, cortical and infra-tentorial) with relative gaining of 28%, 85% and 63% respectively. A non-significant change was found among the two sequences regarding peri-ventricular white matter, deep white matter and juxta-cortical lesions detecting. Conclusion: Conventionally MRI has corner-stone roles in diagnosing, characterizing and following-up of multi-sclerosis. Finally, we concluded that DIR can be used as a addition to or even as an alternative for typical T2 and FLAIR. Therefore, we strongly recommend the addition of DIR sequences in the everyday MR protocol of MS cases.

Double Inversion Recovery Magnetic Resonance Imaging in Identifying Focal Cortical Dysplasia

2016 ◽  
Vol 61 ◽  
pp. 87-93 ◽  
Author(s):  
Lily C. Wong-Kisiel ◽  
Jeffrey W. Britton ◽  
Robert J. Witte ◽  
Kristen M. Kelly-Williams ◽  
Amy L. Kotsenas ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Inversion Recovery ◽  
Double Inversion Recovery ◽  
Resonance Imaging

scholarly journals Intracortical lesions by 3T magnetic resonance imaging and correlation with cognitive impairment in multiple sclerosis

2011 ◽  
Vol 17 (9) ◽  
pp. 1122-1129 ◽  
Author(s):  
Flavia Nelson ◽  
Sushmita Datta ◽  
Nereyda Garcia ◽  
Nigel L Rozario ◽  
Francisco Perez ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Magnetic Resonance ◽  
Cognitive Status ◽  
Inversion Recovery ◽  
Cortical Lesions ◽  
Resonance Imaging

Background: Accurate classification of multiple sclerosis (MS) lesions in the brain cortex may be important in understanding their impact on cognitive impairment (CI). Improved accuracy in identification/classification of cortical lesions was demonstrated in a study combining two magnetic resonance imaging (MRI) sequences: double inversion recovery (DIR) and T1-weighted phase-sensitive inversion recovery (PSIR). Objective: To evaluate the role of intracortical lesions (IC) in MS-related CI and compare it with the role of mixed (MX), juxtacortical (JX), the sum of IC + MX and with total lesions as detected on DIR/PSIR images. Correlations between CI and brain atrophy, disease severity and disease duration were also sought. Methods: A total of 39 patients underwent extensive neuropsychological testing and were classified into normal and impaired groups. Images were obtained on a 3T scanner and cortical lesions were assessed blind to the cognitive status of the subjects. Results: Some 238 cortical lesions were identified (130 IC, 108 MX) in 82% of the patients; 39 JX lesions were also identified. Correlations between CI and MX lesions alone ( p = 0.010) and with the sum of IC + MX lesions ( p = 0.030) were found. A correlation between severity of CI and Expanded Disability Status Scale was also seen ( p = 0.009). Conclusion: Cortical lesions play an important role in CI. However, our results suggest that lesions that remain contained within the cortical ribbon do not play a more important role than ones extending into the adjacent white matter; furthermore, the size of the cortical lesion, and not the tissue-specific location, may better explain their correlation with CI.

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