COUNTING THE FETAL HEART BEAT

JAMA ◽  
1927 ◽  
Vol 88 (13) ◽  
pp. 1000 ◽  
Author(s):  
Joseph B. De Lee
Keyword(s):  
2019 ◽  
Vol 66 (12) ◽  
pp. 3310-3319 ◽  
Author(s):  
Chen Lin ◽  
Hui-Ming Yeh ◽  
Men-Tzung Lo ◽  
Chien-Hung Yeh ◽  
Cheng-Yen Wang ◽  
...  

2015 ◽  
Vol 9 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Zheng Wei ◽  
Wei Xueyun ◽  
Zhong Jian Jian ◽  
Liu Hongxing

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Shinji Tanigaki ◽  
Chie Nagata ◽  
Kazunori Ueno ◽  
Nobuaki Ozawa ◽  
Shinichi Nagaoka ◽  
...  

Background. Caesarean scar pregnancy (CSP) is a rare ectopic pregnancy associated with life-threatening complications. To date, no therapeutic protocols have been established. Sono-guided local methotrexate (MTX) injection is a relatively easy and low-invasive treatment. Additional systemic MTX is sometimes needed for CSP cases, especially when β-subunit human chorionic gonadotropin (β-hCG) levels are >20,000 mIU/ml at diagnosis. We report on six cases of CSP treated with local MTX injection, five of which received combined local treatment. Methods. Under intravenous anesthesia, six CSPs including a case with β-hCG levels >20,000 mIU/ml received MTX injection to the gestational sac. Five cases received gestational sac aspiration. Three cases had additional local potassium chloride injection and one case had a saline injection aiming at the fetal heart beat concurrent with MTX injection. MTX was administered weekly if β-hCG levels stayed beyond the expected values. Outcomes. All cases achieved β-hCG normalization without additional systemic MTX, with one case having a successful pregnancy after treatment. Conclusion. Sono-guided local MTX injection with concurrent local treatment might be a potentially effective approach for CSP cases. The accumulation of further cases is necessary to confirm this.


2018 ◽  
Vol 7 (3) ◽  
pp. 408-411
Author(s):  
Isao Takehara ◽  
Toshifumi Takahashi ◽  
Kuniaki Ota ◽  
Nobuhiko Ohta ◽  
Hideki Mizunuma ◽  
...  

Objectives: Monozygotic triplet pregnancy very rarely occurs in assisted reproductive technology (ART) treatment. The present study reported two cases of trichorionic triplet pregnancies after single embryo transfer (SET) and reviewed the literature in this regard. Case Presentation: In the first case, a 29-year-old female underwent the long protocol using gonadotropin-releasing hormone analogue and one full blastocyst was transferred in a fresh cycle. At 6 gestational weeks, three gestational sacs were clearly observed, while only one fetus with fetal heart beat was found after one week. In the second case, a 39-year-old female underwent intracytoplasmic sperm injection treatment and seven embryos were frozen accordingly. After assisted hatching, one completely expanded blastocyst was transferred during a hormone replacement cycle. Three gestational sacs with three yolk sacs were observed at 6 gestational weeks. Finally, two fetuses with fetal heart beat were found after one week. Conclusions: Overall, although the developmental mechanisms of monozygotic triplets are unknown, clinicians should be aware of the possibility of multiple pregnancies under SET.


2018 ◽  
Vol 10 (3) ◽  
pp. 158-173 ◽  
Author(s):  
Carla Tomassetti ◽  
David Adamson ◽  
Aydin Arici ◽  
Michel Canis ◽  
Peter Hompes ◽  
...  

Background: Clinical management of endometriomas, prior to starting treatment with assisted reproductive technologies (ART), has since long been a matter of debate. Whereas cystectomy has been advocated in the past, recently more evidence has emerged on the potential negative effect of surgery on ovarian reserve. Parallel to this, prolonged downregulation with GnRH-a (gonadotropin-releasing hormone agonists) has been described to improve ART pregnancy rates in women with endometriosis. However, none of these strategies have been assessed in a large randomized controlled trial. The aim of the EndoART study is to assess whether ovarian surgery or prolonged GnRH-a downregulation result in higher pregnancy rates after ART compared to no intervention in women with endometrioma(s). Methods/design: A parallel randomized multi-center trial has been designed to compare ART pregnancy rates in three different treatment groups: no intervention, ovarian surgery, and prolonged hormonal suppression by GnRH-a prior to ART. The primary outcome measure studied is the clinical pregnancy rate with fetal heart-beat within 6 months after initiation of a fresh ART cycle. Secondary outcome measures studied include live birth rate after one initiated fresh ART cycle, cumulative clinical pregnancy rate with fetal heart-beat and live birth rates (after one fully completed ART cycle: initiated fresh + eventual associated frozen embryo transfer cycles), ART–specific data (e.g. number of oocytes, number of good quality embryos), complications, pelvic pain, and quality of life. Conclusion: This trial may answer the most frequently asked questions by both women with endometriosis and physicians: how do you treat endometrioma in women prior to treatment with ART?


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ali Sami Gurbuz ◽  
Ahmet Salvarci ◽  
Necati Ozcimen ◽  
Ayse Gul Zamani

The patient was diagnosed with nonmosaic 47, XXY Klinefelter Syndrome with the AZF deletion absent and SRY+. The nonmosaic 47, XXY karyotype was confirmed on a skin biopsy chromosomal analysis. Using only ejaculate motile sperms, 11 oocytes underwent ICSI and were placed rapidly in a time lapse (Embryoscope ©) with a specific culture dish. Biopsies were performed on six embryos on the 3rd day, and numerical chromosomal abnormalities were observed using the FISH test before transfer. PGS results were normal in only two embryos with normal morphokinetics in the Embryoscope. For clinical confirmation of pregnancy, ultrasonographic examination was performed during the 7th week of pregnancy, and two gestational sacs and fetal heart beat were observed.


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