DOES DIABETES MELLITUS PREDISPOSE THE PATIENT TO THE PYOGENIC SKIN INFECTIONS?

1942 ◽  
Vol 118 (16) ◽  
pp. 1357 ◽  
Author(s):  
JOHN R. WILLIAMS
Keyword(s):  
Diabetes Mellitus ◽  
Skin Infections

DIABETES MELLITUS AND PYOGENIC SKIN INFECTIONS

JAMA ◽  
1942 ◽  
Vol 119 (18) ◽  
pp. 1525
Author(s):  
H. M. C. Luykx
Keyword(s):  
Diabetes Mellitus ◽  
Skin Infections

scholarly journals Macro and microscopic characters of Maerua oblongifolia (Forssk.) A. Rich leaf

2020 ◽  
pp. 182-186
Author(s):  
G. Prabhakar ◽  
K. Shailaja ◽  
P. Kamalakar
Keyword(s):  
Diabetes Mellitus ◽  
Vascular Bundle ◽  
Transverse Section ◽  
Lower Limbs ◽  
Vascular Bundles ◽  
Skin Infections ◽  
Ground Tissue ◽  
Abdominal Colic ◽  
The Family ◽  
Powder Analysis

The paper deals with a detailed investigation on the leaves of Maerua oblongifolia (Forssk.) A. Rich. which includes it’s morphological, anatomical and powder analysis. It is a low woody bushy under-shrub belonging to the family Capparaceae. The leaves are used in treatment of as fever, ear ache, stomach ache, skin infections, urinary calculii, diabetes mellitus, epilepsy, rigidity in lower limbs, and abdominal colic. The leaf amphistomatic, with mostly anamocytic, few tetracytic stomata. In transverse section of leaf is ribbed on either sides at midvein, epidermis one layered. Mesophyll differentiated into palisade and spongy tissues. Ground tissue of midvein differentiated into palisade, collenchyma and parenchyma. The midvien consists of one large oval shaped vascular bundles arranged are at the centre. Petiole in transverse section is circular adaxially small, grooved at centre and epidermis is having one layered, a single circular vascular bundle present at the centre, vascular bundle is enclosed by endodermis. The powder microscopic and organoleptic characters are also presented in this study. This study would helps as an appropriate source for authentification of the present studied drug.  

scholarly journals Skin Infection Caused by Serratia marcescens in a Patient with Diabetes Mellitus

2021 ◽  
pp. 17-20
Author(s):  
Dong Heon Lee ◽  
Dong Hyek Jang ◽  
Mi Youn Park ◽  
Jiyoung Ahn ◽  
Hye Jung Jung
Keyword(s):  
Diabetes Mellitus ◽  
Serratia Marcescens ◽  
Hypertrophic Scar ◽  
Skin Infection ◽  
Intralesional Injection ◽  
Skin Infections ◽  
Thickness Skin ◽  
Immunosuppressed Patients ◽  
Bacterium Strain ◽  
Typical Skin

Serratia marcescens is an uncommon gram-negative bacterium strain that does not cause skin infections in healthy individuals. However, it is rarely reported as the causative agent of infection in immunosuppressed patients or in nosocomial infections. A 51-year-old man was admitted to a hospital presenting with pus and pain that had developed a month ago on a hypertrophic scar area of the back. Although he was on medication for diabetes mellitus, his blood sugar level was poorly controlled. In addition, two months earlier, he received an intralesional injection of 40 mg/mL triamcinolone twice for the hypertrophic scar of the back. S. marcescens was identified in the wound culture. His condition improved after ceftriaxone administration, debridement, and split-thickness skin grafts. Although S. marcescens is an infrequent cause of skin infections, it is important to remember that it may cause infection in some patients and that the course of the disease may be worse than that in a typical skin infection with poor prognosis.

scholarly journals Type, course and outcome of community acquired infections in hospitalized diabetics

2010 ◽  
Vol 1 (1) ◽  
pp. 6
Author(s):  
Eirini Tsakiridou ◽  
Konstantinos Argyriou ◽  
Dimosthenis Makris ◽  
Epameinondas Zakynthinos
Keyword(s):  
Diabetes Mellitus ◽  
Skin Infections ◽  
Urinary Infections ◽  
Increased Risk ◽  
Serious Infections ◽  
Patients With Diabetes ◽  
Immune Deficiencies ◽  
Log Odds ◽  
Prolonged Hospital ◽  
Control Study

Diabetes mellitus has been associated with increased frequency of serious infections which are attributed to immune deficiencies. The aims of this study were to investigate the type, course and outcomes of community acquired infections, and especially bacteremia in diabetics hospitalized for infection. One hundred and thirty-four consecutive patients (67 diabetics and 67 non-diabetics) matched for age, who were admitted to a general District Hospital in Greece due to infection, were included in this case control study. Diabetics presented urinary infections (46.3% vs. 26.8%, P=0.006), skin infections (9% vs. 0%, P=0.007) and bacteremia (11.1% vs. 1.5%, P=0.023) more often than controls. The most common microorganisms in diabetics were Escherichia coli, Klebsiella pneumoniae, Streptococcus species and fungi. Diabetics had a significantly prolonged hospital stay (6.7±5.4 vs. 4.5±2.4, P=0.003) compared to controls. In-hospital mortality was similar in both groups (10.4% vs. 3%, P=0.082) but diabetics had an increased risk from death due to bacteremia (Log-odds 4.2, SE=1.1, P<0.0001). Although the analyzed cohorts are small, we found that patients with diabetes mellitus have longer hospitalization related to infections and are at increased risk of bacteremia which may result in adverse outcome.

P1019CANAGLIFLOZIN AND RISK OF SKIN AND SOFT TISSUE INFECTIONS IN PEOPLE WITH DIABETES MELLITUS AND KIDNEY DISEASE - A POST-HOC ANALYSIS OF THE CREDENCE TRIAL

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Amy Kang ◽  
Brendan Smyth ◽  
Brendon Neuen ◽  
Hiddo Lambers Heerspink ◽  
Gian Luca Di Tanna ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Soft Tissue ◽  
Kidney Disease ◽  
Skin Infections ◽  
Soft Tissue Infections ◽  
Post Hoc Analysis ◽  
Intention To Treat ◽  
Post Hoc ◽  
Treat Population

Abstract Background and Aims The skin’s hypertonic microenvironment has a hypothesized protective antimicrobial function that may be disrupted by SGLT2i. The association between sodium glucose cotransporter inhibitors (SGLT2i) and genital mycotic infections is well established, but it is not known if these agents increase the risk of other skin and soft tissue infections (SSTI). We aimed to describe SSTI in the CREDENCE trial, and determine whether canagliflozin affects the risk of skin and soft tissue infections (SSTIs) overall and in subgroups. Method We performed a post-hoc analysis of the CREDENCE trial that randomised people with type 2 diabetes and albuminuric stage 2 and 3 chronic kidney disease to either canagliflozin 100mg daily or placebo. Infections reported as adverse events were assessed by two blinded authors following predetermined criteria for SSTI with discrepancies resolved by consensus. We analysed the risks of SSTIs in the on-treatment population as the more conservative approach, with a sensitivity analysis conducted in the intention-to-treat population. Univariable time-to first-event regression models were assessed. Results Overall 373/4397 (8.5%) participants experienced 478 events comprising 252 bacterial skin infections (including 2 episodes of necrotising fasciitis), 94 fungal skin infections, 109 other skin infections and 23 soft tissue infections. Of these, 136/478 (28%) were serious. Drug was continued in 290/373 (78%) of first events, with similar frequency of subsequent events between groups (31/133 (23%) and 33/157 (21%) for those continuing canagliflozin and placebo respectively). In both cases of necrotising fasciitis, drug was withdrawn and the participants recovered.Canagliflozin did not increase the risk of SSTI (HR 0.85 [95% Confidence Interval (CI) 0.69-1.04] p=0.11) (Figure 1). Results were similar in the intention-to-treat population (HR 0.88 [95% CI 0.73-1.07] p=0.20), in analyses confined to serious SSTI (HR 0.83 [95% CI 0.58-1.21] p=0.33), and in the predefined subgroups. Conclusion Although other studies suggest that SGLT2i may reduce the sodium content of the skin, we found that canagliflozin does not increase the risk of skin and soft tissue infections, overall or in any subgroup, in people with type 2 diabetes mellitus and albuminuric chronic kidney disease.

scholarly journals Facial Abscess due to Staphylococcus aureus in Patient with Type 2 Diabetes Mellitus: Case Report

2021 ◽  
Vol 4 (2) ◽  
pp. 121
Author(s):  
Dian Galuh Maharani ◽  
Hermina Novida
Keyword(s):  
Diabetes Mellitus ◽  
Staphylococcus Aureus ◽  
Correct Diagnosis ◽  
Strong Positive Correlation ◽  
Skin Infections ◽  
Soft Tissue Infections ◽  
Effective Management ◽  
Life Threatening ◽  
Incision Drainage

Diabetes mellitus (DM) is a chronic disease with an increasing frequency over the last decade. DM patient has higher risk of infection than people without diabetes. Several literatures suggest a strong positive correlation between hyperglycemia and skin infections. Skin and soft tissue infections (SSTIs), including abscess which commonly caused by Staphylococcus aureus, could lead to severe and life-threatening infections. The correct diagnosis and effective management therapy should be needed to prevent further complications and reduce morbidity and mortality. We report a case about facial abscess caused by S. aureus in diabetic patient that healed after got incision drainage and antibiotics.

Peer Relationship Problems in Children with Tourette's Disorder or Diabetes Mellitus

1998 ◽  
Vol 39 (5) ◽  
pp. 663-668 ◽  
Author(s):  
Harry N. Bawden ◽  
Aidan Stokes ◽  
Carol S. Camfield ◽  
Peter R. Camfield ◽  
Sonia Salisbury
Keyword(s):  
Diabetes Mellitus ◽  
Peer Relationship ◽  
Tourette’S Disorder ◽  
Relationship Problems ◽  
Tourette's Disorder

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

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