Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms

Objective. Keratosis pilaris (KP) is a common condition which can frequently be cosmetically disturbing. Topical treatments can be used with limited efficacy. The objective of this study is to evaluate the effectiveness and safety of fractional carbon dioxide (CO2) laser for the treatment of KP.Patients and Methods. A prospective, randomized, single-blinded, intraindividual comparative study was conducted on adult patients with KP. A single session of fractional CO2laser was performed to one side of arm whereas the contralateral side served as control. Patients were scheduled for follow-up at 4 and 12 weeks after treatment. Clinical improvement was graded subjectively by blinded dermatologists. Patients rated treatment satisfaction at the end of the study.Results. Twenty patients completed the study. All patients stated that the laser treatment improved KP lesions. At 12-week follow-up, 30% of lesions on the laser-treated side had moderate to good improvement according to physicians’ global assessment (p=0.02). Keratotic papules and hyperpigmentation appeared to respond better than the erythematous component. Four patients with Fitzpatrick skin type V developed transient pigmentary alteration.Conclusions. Fractional CO2laser treatment may be offered to patients with KP. Dark-skinned patients should be treated with special caution.

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Clinical evaluation of a microablative/fractional carbon dioxide laser for the treatment of photodamage and scars

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2009.11.547 ◽

2010 ◽

Vol 62 (3) ◽

pp. AB142

Keyword(s):

Carbon Dioxide ◽

Clinical Evaluation ◽

Carbon Dioxide Laser ◽

Fractional Carbon Dioxide Laser

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Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-Rich Plasma

Dermatologic Surgery ◽

10.1111/j.1524-4725.2011.01916.x ◽

2011 ◽

Vol 37 (4) ◽

pp. 463-468 ◽

Cited By ~ 68

Author(s):

Jung-Im Na ◽

Jee-Woong Choi ◽

Hye-Ryung Choi ◽

Jeong-Bok Jeong ◽

Kyoung-Chan Park ◽

...

Keyword(s):

Carbon Dioxide ◽

Carbon Dioxide Laser ◽

Platelet Rich Plasma ◽

Laser Resurfacing ◽

Rapid Healing ◽

Fractional Carbon Dioxide Laser ◽

Autologous Platelet Rich Plasma ◽

Autologous Platelet

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Fractional carbon dioxide laser in recalcitrant vulval lichen sclerosus

Australasian Journal of Dermatology ◽

10.1111/ajd.12305 ◽

2015 ◽

Vol 57 (1) ◽

pp. 39-43 ◽

Cited By ~ 25

Author(s):

Andrew Lee ◽

Adrian Lim ◽

Gayle Fischer

Keyword(s):

Carbon Dioxide ◽

Carbon Dioxide Laser ◽

Lichen Sclerosus ◽

Fractional Carbon Dioxide Laser

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Split face comparative study of microneedling with platelet rich plasma versus Fractional carbon dioxide laser with platelet rich plasma in treatment of atrophic post acne scars

QJM ◽

10.1093/qjmed/hcab093.001 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Mohamed Abd Elnaeem Sallam ◽

Khaled El Zawahry ◽

Abdul Rahman Muhammed Ali Mustafa

Keyword(s):

Carbon Dioxide ◽

Co2 Laser ◽

Carbon Dioxide Laser ◽

Platelet Rich Plasma ◽

Fractional Co2 Laser ◽

Acne Scars ◽

Significant Difference ◽

Before And After ◽

The Face ◽

Fractional Carbon Dioxide Laser

Abstract Background Acne scars, is a challenge for dermatologists, despite having multiple treatment modalities like microneedling, dermabrasion, Fractional CO2 Laser, dermal fillers, etc. However, monotherapy has been hardly satisfactory because of the polymorphism seen with the scars. Objective Comparison between microneedling with platelet rich plasma versus Fractional carbon dioxide laser with platelet rich plasma in treatment of atrophic post acne scars. Patients and methods This study was carried out in department of dermatology, venereology and andrology, in Kobry El-Kobba Military complex during the period (from September 2018 to July 2020 ) on 20 patients of both sexes aged from 20 to 60 years old presenting with Goodman and Baron Grade II, III, IV acne scars . Results The study revealed a statistically significant difference (p = 0.017) between Goodman and Baron scar grades on the right side of the face before and after treatment indicating that microneedling with platelet rich plasma was effective in improving acne scars. Also, there is a statistically significant difference (p = 0.010) between Goodman and Baron scar grades on the left side of the face before and after treatment, indicating that fractional CO2 laser with platelet rich plasma was effective in improving acne scars. Conclusion and recommendation Further controlled and randomized studies are needed to validate our findings in a larger cohort of patients and longer follow up. Also, number of sessions might be more than 3 sessions.

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