Prognostic Variables: Categorizing a Prognostic Variable: Review of Methods, Code for Easy Implementation and Applications to Decision-Making about Cancer Treatments

2005 ◽  
pp. 187-208 ◽  
Author(s):  
Madhu Mazumdar ◽  
Jill R. Glassman
2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Philip D Poorvu ◽  
A Lindsay Frazier ◽  
Angela M Feraco ◽  
Peter E Manley ◽  
Elizabeth S Ginsburg ◽  
...  

AbstractCancer treatments may compromise the fertility of children, adolescents, and young adults, and treatment-related infertility represents an important survivorship issue that should be addressed at diagnosis and in follow-up to ensure optimal decision-making, including consideration of pursuing fertility preservation. Risk of infertility varies substantially with patient and treatment factors. The ability to accurately assess fertility risk for many patients is hampered by limitations of the current literature, including heterogeneity in patient populations, treatments, and outcome measures. In this article, we review and synthesize the available data to estimate fertility risks from modern cancer treatments for both children and adult cancer survivors to enable clinicians to counsel patients about future fertility.


2021 ◽  
Vol 50 (1) ◽  
pp. 47
Author(s):  
Semir Vranic ◽  
Zoran Gatalica

<p>This review provides a brief overview of the state-of-the-art molecular pathology approaches emphasizing the increasingly important pathology role in clinical precision cancer medicine. Recent advances in molecular biology and genetics have tremendously affected the practice of anatomic pathology, gradually transforming it from a morphology-based into a molecular- based discipline. Molecular diagnostics has a long tradition in pathology, especially in clinical pathology. The improvement of methodology for genomic testing in recent years has made it one of the cornerstones of precision cancer medicine. The decisions related to cancer treatments are no longer solely based on the histopathological diagnosis. Various genomic analyses of human cancers are being incorporated into diagnostic and decision-making algorithms.</p><p><strong> Conclusion</strong>. The pathologists continue to play an essential role in developing and implementing molecular and genomic tests in practice and communicate the results and their relevance with clinicians. Such activities are of utmost importance for successfully translating scientific advancements into a benefit to patients (“next-generation pathologists”).</p>


Author(s):  
Jose Antonio Miñarro-Giménez ◽  
Teddy Miranda-Mena ◽  
Rodrigo Martínez-Béjar ◽  
Jesualdo Tomás Fernández-Breis

BMJ ◽  
2008 ◽  
Vol 337 (aug11 2) ◽  
pp. a1243-a1243
Author(s):  
T. S Maughan ◽  
J. Rule

2009 ◽  
Vol 141 (2) ◽  
pp. 162-165 ◽  
Author(s):  
Martin J. Burton ◽  
Marion E. Couch ◽  
Richard M. Rosenfeld

The “Cochrane Corner” is a quarterly section in the Journal that highlights systematic reviews relevant to otolaryngology–head and neck surgery, with invited commentary to aid clinical decision making. This installment features a Cochrane Review entitled “Homeopathic medicines for adverse effects of cancer treatments,” which finds preliminary data to support efficacy of topical calendula for radiation-induced dermatitis and a proprietary mouthwash for chemotherapy-induced stomatitis.


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