THE EFFECT OF SUBACUTE INTOXICATION WITH ETHYLENE CHLOROHYDRIN ON IMMUNE RESPONSES, TH1 AND TH2 LYMPHOCYTE FUNCTION AND CYTOKINE LEVELS IN RATS BLOOD

2017 ◽  
pp. 27-30
Author(s):  
P. F. Zabrodskii ◽  
V. V. Maslyakov ◽  
M. S. Gromov
Keyword(s):  
Immune Responses ◽  
Inflammatory Cytokine ◽  
Albino Rats ◽  
Lymphocyte Function ◽  
Ethylene Chlorohydrin ◽  
Immunoregulatory Cytokines ◽  
Cytokine Levels ◽  
Th1 And Th2 Lymphocytes ◽  
Cellular Immune ◽  
Th1 And Th2

In experiments on outbred albino rats, it was established that subacute intoxication with ethylene chlorohydrin (0.2 LD50 daily for 4 days) causes a decrease in Th1 and Th2 lymphocytes function to the same extent, diminishes parameters of humoral and cellular immune responses and the content of immunoregulatory cytokines IFN- , IL-2, IL-4 in blood, increases concentrations of pro-inflammatory cytokine IL-6 and anti-inflammatory cytokine IL-10.

Acute Ethylene Chlorohydrin Poisoning: Experience of a Poison Control Center

2001 ◽  
Vol 39 (6) ◽  
pp. 587-593 ◽  
Author(s):  
Jou-Fang Deng ◽  
Chen-Chang Yang ◽  
Wei-Jen Tsai ◽  
Jiin Ger ◽  
Ming-Ling Wu
Keyword(s):  
Poison Control ◽  
Poison Control Center ◽  
Ethylene Chlorohydrin ◽  
Control Center

scholarly journals Acute Poisoning Caused by Ingestion of Ethylene Chlorohydrin

1953 ◽  
Vol 10 (3) ◽  
pp. 161-163
Author(s):  
F. Ballotta ◽  
P. Bertagni ◽  
F. M. Troisi
Keyword(s):  
Acute Poisoning ◽  
Ethylene Chlorohydrin

Determination of 2-Chloroethanol in Honey, Beeswax, and Pollen

1983 ◽  
Vol 66 (3) ◽  
pp. 659-662
Author(s):  
Gary W Bruns ◽  
Robert A Currie
Keyword(s):  
Ethylene Oxide ◽  
Maximum Amount ◽  
Ethylene Chlorohydrin ◽  
Liquid Chromatograph ◽  
Naturally Occurring ◽  
Specific Detector

Abstract Procedures were developed and tested for the determination of residues of 2-chloroethanol (ethylene chlorohydrin, ECH) in honey, beeswax, and pollen. Recoveries of ECH from fortified samples averaged 91,87, and 89%, respectively, for each substrate. The maximum amount of ECH found in substrate fumigated with ethylene oxide was 36 μg/g in honey, 124 μg/g in beeswax, and 132 μg/g in pollen. A tendency was noted for darker waxes, which contain larger amounts of naturally occurring chlorides than light-colored waxes, to contain the greater amounts of ECH. A gas-liquid chromatograph equipped with a Dohrmann halogen-specific detector was used for identification and quantitation.

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