Ethylene Chlorohydrin

2017 ◽  
pp. 443-444
Author(s):  
Pradyot Patnaik
Author(s):  
P. F. Zabrodskii ◽  
V. V. Maslyakov ◽  
M. S. Gromov

In experiments on outbred albino rats, it was established that subacute intoxication with ethylene chlorohydrin (0.2 LD50 daily for 4 days) causes a decrease in Th1 and Th2 lymphocytes function to the same extent, diminishes parameters of humoral and cellular immune responses and the content of immunoregulatory cytokines IFN- , IL-2, IL-4 in blood, increases concentrations of pro-inflammatory cytokine IL-6 and anti-inflammatory cytokine IL-10.


2001 ◽  
Vol 39 (6) ◽  
pp. 587-593 ◽  
Author(s):  
Jou-Fang Deng ◽  
Chen-Chang Yang ◽  
Wei-Jen Tsai ◽  
Jiin Ger ◽  
Ming-Ling Wu

1953 ◽  
Vol 10 (3) ◽  
pp. 161-163
Author(s):  
F. Ballotta ◽  
P. Bertagni ◽  
F. M. Troisi

1983 ◽  
Vol 66 (3) ◽  
pp. 659-662
Author(s):  
Gary W Bruns ◽  
Robert A Currie

Abstract Procedures were developed and tested for the determination of residues of 2-chloroethanol (ethylene chlorohydrin, ECH) in honey, beeswax, and pollen. Recoveries of ECH from fortified samples averaged 91,87, and 89%, respectively, for each substrate. The maximum amount of ECH found in substrate fumigated with ethylene oxide was 36 μg/g in honey, 124 μg/g in beeswax, and 132 μg/g in pollen. A tendency was noted for darker waxes, which contain larger amounts of naturally occurring chlorides than light-colored waxes, to contain the greater amounts of ECH. A gas-liquid chromatograph equipped with a Dohrmann halogen-specific detector was used for identification and quantitation.


1993 ◽  
Vol 76 (2) ◽  
pp. 292-296 ◽  
Author(s):  
Kumiko Sasaki ◽  
Keiji Kijima ◽  
Mitsuharu Takeda ◽  
Shigeo Kojima

Abstract A simple specific determination method was developed for ethylene oxide (EO) and ethylene chlorohydrin (ECH) in cosmetics and surfactants. EO is desorbed from samples by using a nitrogen stream and absorbed into acidic potassium iodide solution, where it is converted to ethylene iodohydrin (EIH). Any remaining ECH in the samples is converted to EO by the addition of sodium hydroxide, and the desorption procedure is repeated with a fresh acidic potassium iodide absorbing solution. EIH is extracted with benzene and determined by gas chromatography with electron capture detection. EO and ECH contents in the samples are calculated from EIH results. Recoveries from water and shampoo samples were 70.3 ± 5.4 and 58.9 ± 1.2%, respectively, for EO and 66.3 ± 4.0 and 64.5 ± 4.6%, respectively, for ECH. Detection limits in 0.2-2.0 g samples were in the 0.005-0.03 μg/g range for EO and 0.01-0.07 μg/g for ECH. High levels of EO (30-394 μg/g as ECH) were found in 5 of 18 polyoxyethylated surfactant samples, but only small amounts (0.07-4.0 μg/g) of ECH were detected in the samples. EO was not detected in cosmetic samples tested, but ECH was present in small quantities (≤1.11 μg/g).


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