Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants

2015 ◽  
Author(s):  
Eugene Dempsey ◽  
Mohan Pammi ◽  
Anthony C Ryan ◽  
Keith J Barrington
Keyword(s):  
Newborn Infants ◽  
Mortality And Morbidity ◽  
Resuscitation Training ◽  
Training Programmes

scholarly journals Newborns at risk of Covid-19 ― lessons from the last year

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Malika D. Shah ◽  
Ola Didrik Saugstad
Keyword(s):  
Horizontal Transmission ◽  
Mode Of Delivery ◽  
Newborn Infants ◽  
World Health ◽  
Premature Delivery ◽  
Mortality And Morbidity ◽  
Skin Contact ◽  
Cord Clamping ◽  
Increased Risk ◽  
Health Organization

Abstract After more than 1 year of the SARS-CoV-2 pandemic, a great deal of knowledge on how this virus affects pregnant women, the fetus and the newborn has accumulated. The gap between different guidelines how to handle newborn infants during this pandemic has been minimized, and the American Academy of Pediatrics (AAP)’s recommendations are now more in accordance with those of the World Health Organization (WHO). In this article we summarize present knowledge regarding transmission from mother to the fetus/newborn. Although both vertical and horizontal transmission are rare, SARS-CoV-2 positivity is associated with an increased risk of premature delivery and higher neonatal mortality and morbidity. Mode of delivery and cord clamping routines should not be affected by the mother’s SARS-CoV-2 status. Skin to skin contact, rooming in and breastfeeding are recommended with necessary hygiene precautions. Antibodies of infected or vaccinated women seem to cross both the placenta and into breast milk and likely provide protection for the newborn.

Group B Streptococcal Infections in Neonates

1979 ◽  
Vol 1 (1) ◽  
pp. 5-15
Author(s):  
Carol J. Baker
Keyword(s):  
Group B Streptococcus ◽  
Newborn Infants ◽  
Neonatal Infection ◽  
Etiologic Agent ◽  
Diagnostic Methods ◽  
Bacterial Disease ◽  
Absolute Increase ◽  
Mortality And Morbidity ◽  
The Past ◽  
Group B

β-Hemolytic streptococci of Lancefield group B have been causally linked to neonatal disease since 1938, but only in the last decade has the group B Streptococcus become the leading etiologic agent for bacteremia and/or meningitis occurring during the first two months of life. Neither the reasons for the emergence of this organism nor the shifts over the past 40 years in the prevalence of various bacteria responsible for neonatal infection has been adequately explained. However, the importance of the group B Streptococcus as a frequent cause of neonatal mortality and morbidity demands a thorough understanding of the epidemiology and pathogenesis, clinical features, diagnostic methods, and management of these infections by physicians caring for newborn infants. INCIDENCE The common occurrence of neonatal group B streptococcal septicemia and meningitis in several geographically distant centers since 1970 has allowed the relatively precise determination of attack rates for early onset type (≤5 days) infection. Reported attack rates have been surprisingly uniform, varying from 1.3/1,000 to 4.0/1,000 live births (Table 1). Because the attack rates for serious neonatal infections associated with Escherichia coli and other maternally acquired coliform organisms have been constant since 1960, the appearance of the group B Streptococcus resulted in an absolute increase in the incidence of neonatal bacterial disease during the past decade in many hospitals in this country.

Role of N-Terminal Pro-brain Natriuretic Peptide in the Early Diagnosis of Neonatal Sepsis

2019 ◽  
Vol 14 (05) ◽  
pp. 228-234
Author(s):  
Nilufer Okur ◽  
Mehmet Buyuktiryaki ◽  
Nurdan Uras ◽  
Mehmet Yekta Oncel ◽  
Halid Halil ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Neonatal Intensive Care ◽  
Late Onset ◽  
Newborn Infants ◽  
Diagnostic Biomarker ◽  
Predictive Values ◽  
Mortality And Morbidity ◽  
Late Onset Sepsis

Objective Sepsis is one of the most significant contributors to mortality and morbidity in the neonatal population. The need to find specific biomarkers that provide meaningful information about the diagnosis of sepsis is still ongoing. This study aimed to investigate the utility of N-terminal pro-brain natriuretic peptide (NT-proBNP) as a diagnostic biomarker in newborn infants with late-onset sepsis. Methods A prospective, observational study was conducted in the neonatal intensive care unit between July 2016 and January 2017. The patients suspected of having late-onset sepsis and meeting the selection criteria were included in the study, and serial measurements of white blood cell count, serum C-reactive protein (CRP), plasma interleukin (IL) 6, and whole blood NT-proBNP levels were performed. Results The study included 87 patients diagnosed with sepsis and 35 control patients. The median NT-proBNP levels were higher in septic patients (58 [22–169] vs. 14 [7–21]; p < 0.001), showing a significant correlation with CRP and IL-6 levels (r = 0.327, p < 0.01 and r = 0.216, p < 0.05, respectively). The optimal diagnostic cutoff value for differentiating sepsis was 27.5 pg/mL. Predictive parameters of NT-proBNP, such as sensitivity (72%) and specificity (86%), were comparable to those of CRP and IL-6 for the early diagnosis of sepsis in neonates. Conclusion Plasma NT-proBNP levels were higher in septic neonates, and the predictive values were comparable to those of CRP and IL-6. However, these values were not high enough to make it a reliable diagnostic biomarker for identifying neonates in the early stages of sepsis.

Facilitators and barriers for the implementation of resuscitation training programmes for schoolchildren

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sabine Wingen ◽  
Julia Jeck ◽  
Daniel C. Schroeder ◽  
Sebastian M. Wingen-Heimann ◽  
Ruben M.W.A. Drost ◽  
...  
Keyword(s):  
Resuscitation Training ◽  
Facilitators And Barriers ◽  
Training Programmes

Newborn Resuscitation Training Programmes Reduce Early Neonatal Mortality

Neonatology ◽  
2016 ◽  
Vol 110 (3) ◽  
pp. 210-224 ◽  
Author(s):  
Mohan Pammi ◽  
Eugene M. Dempsey ◽  
C. Anthony Ryan ◽  
Keith J. Barrington
Keyword(s):  
Neonatal Mortality ◽  
Newborn Resuscitation ◽  
Early Neonatal Mortality ◽  
Resuscitation Training ◽  
Training Programmes

scholarly journals Mapping Evidence of Neonatal Resuscitation Training on Practice of Unskilled Birth Attendants in Low- Resource Countries: a scoping review protocol (Preprint)

2020 ◽  
Author(s):  
Adenike Adebola Olaniyi
Keyword(s):  
Scoping Review ◽  
Full Text ◽  
Meta Analysis ◽  
Grey Literature ◽  
Newborn Infants ◽  
Neonatal Resuscitation ◽  
Birth Asphyxia ◽  
Birth Attendants ◽  
Resuscitation Training ◽  
Review Protocol

BACKGROUND Competence in neonatal resuscitation of the newborn is very critical to ensure the safety and health of the newborn infants. Effects of acquisition of neonatal resuscitation skills improve self-efficacy, thereby reducing neonatal mortality as a result of asphyxia. About one-quarter of all neonatal deaths globally are caused by birth asphyxia. The need for neonatal resuscitation is most imperative in a resource-constrained setting, where access to intrapartum obstetric care is inadequate and poor. OBJECTIVE The protocol describes the methodology of a scoping review on evidence of training in neonatal resuscitation and its association with practice in low-resources countries. The aim of the review is to map available evidence of neonatal resuscitation training proficient on unskilled birth attendants practice. METHODS This scoping review protocol uses the framework proposed by Arksey & O’Malley and refined by Levac et al, published by Joanna Briggs Institute while following the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Review Protocols guidelines. The search strategy was developed with the assistance of the college librarian. Five peer-reviewed data-bases (EBSCOhost (PsychINFO, Wiley online), PubMed, MEDLINE with full-text, Google Scholar (Science Direct), CINAHL Plus with full text EBSCOhost), databases committed to grey literature sources, and reference extraction will be used. Two independent reviewers will screen and extract data. Discrepancies will be resolved by the third reviewer. The extracted data will undergo a descriptive analysis of contextual data and a quantitative analysis using appropriate statistical methods. RESULTS NULL CONCLUSIONS NULL

scholarly journals Neonatal sepsis-blood culture, antibiotic stewardship and clinico-bacteriological study

2020 ◽  
Vol 7 (12) ◽  
pp. 2376
Author(s):  
Purva Shah ◽  
Ketan Gadhvi ◽  
Bharat Muliya ◽  
Khushi Shah
Keyword(s):  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Late Onset ◽  
Newborn Infants ◽  
Tertiary Hospital ◽  
Resistance Pattern ◽  
Bacteriological Study ◽  
Mortality And Morbidity ◽  
Early Onset Sepsis ◽  
Septic Focus

Background: Neonatal sepsis refers to an infection involving bloodstream in newborn infants less than 28 days old. It continues to remain a leading cause of morbidity and mortality among infants, especially in middle and lower-income countries. Neonatal sepsis is divided into 2 groups based on the time of presentation after birth: early-onset sepsis and late-onset sepsis.Methods: This study was done in the neonatal intensive care unit of tertiary hospital, Surendranagar. Study design being observational, data collected from clinical examination and records of the neonates admitted with positive septic screen, neonates admitted with suspected clinical sepsis (temperature >990F or <950F, respiratory rate more than 60 per minute, change in behavior, abnormal cry, not accepting feed, drowsy or unconscious, septic focus on skin or umbilicus, diarrhea and seizures) and neonates admitted with culture positive sepsis.Results: As per this research, neonatal sepsis has more male preponderance, with more commonly occurring in low birth weights and preterm. Klebsiella, Staphylococcus aureus and Pseudomonas being the most isolated organisms. Their resistance pattern, antibiotic profile and newer trends also came across.Conclusions: Neonatal sepsis comes as one of the major causes of mortality and morbidity of the newborns admitted. By this research, analyzing the sex, age, gestational weeks, organism isolated and the antibiotic profile, emerging new resistance and newer useful antibiotics can thus be studied and can be taken as a base for further study as well as evaluation of the same, along with also guiding to manage and treat neonatal sepsis better.

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