Integrin α5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker

Achieving normal or near-normal glycemic control as reflected by HbA1c levels in patients with type 1 diabetes (T1D) is important for preventing the development and progression of chronic complications. Despite delineation and dissemination of HbA1c management targets and advances in insulin pharmacology, insulin delivery systems, and glucose monitoring, the majority of children with T1D do not achieve HbA1c goals. In particular, African Americans are more likely not to reach HbA1c goals and have persistently higher HbA1c than Non-Hispanic Whites. Availability of pumps and other technology has not eliminated the disparity in HbA1c. Multiple factors play a role in the persisting racial disparity in HbA1c outcome. The carefully designed application and deployment of new technology to help the patient/family and facilitate the supportive role of the diabetes management team may be able to overcome racial disparity in glycemic outcome and improve patient quality of life.

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Role of serum ST2 as a prognostic marker in acute MI

Indian Heart Journal ◽

10.1016/j.ihj.2015.10.315 ◽

2015 ◽

Vol 67 ◽

pp. S125

Author(s):

Dattagupta Aditi ◽

I. Sathyamurthy ◽

G. Sengottuvelu ◽

K.N. Srinivasan ◽

Kirubakaran

Keyword(s):

Prognostic Marker ◽

Acute Mi

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Supportive Role of Probiotic Strains in Protecting Rats from Ovariectomy-Induced Cortical Bone Loss

Probiotics and Antimicrobial Proteins ◽

10.1007/s12602-018-9443-6 ◽

2018 ◽

Vol 11 (4) ◽

pp. 1145-1154 ◽

Cited By ~ 14

Author(s):

Nima Montazeri-Najafabady ◽

Younes Ghasemi ◽

Mohammad Hossein Dabbaghmanesh ◽

Pedram Talezadeh ◽

Farhad Koohpeyma ◽

...

Keyword(s):

Bone Loss ◽

Cortical Bone ◽

Cortical Bone Loss ◽

Supportive Role ◽

Probiotic Strains

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The Influence of the Media on Policies in Practice: Hungarian Refugee Resettlement in the Netherlands in 1956

Journal of Migration History ◽

10.1163/23519924-00301002 ◽

2017 ◽

Vol 3 (1) ◽

pp. 22-53

Author(s):

Marlou Schrover ◽

Tycho Walaardt

Keyword(s):

The Netherlands ◽

Government Policies ◽

Policy Makers ◽

Supportive Role ◽

The Press ◽

Freedom Fighters ◽

The Media ◽

Women And Children ◽

Changes Over Time

This article analyses newspaper coverage, government policies and policy practices during the 1956 Hungarian refugee crisis. There were surprisingly few differences between newspapers in the coverage of this refugee migration, and few changes over time. The role of the press was largely supportive of government policies, although the press did criticise the selection of refugees. According to official government guidelines, officials should not have selected, but in practice this is what they attempted to do. The refugees who arrived in the Netherlands did not live up to the image the press, in its supportive role, had created: there were too few freedom fighters, women and children. This article shows that the press had an influence because policy makers did make adjustments. However, in practice selection was not what the media assumed it was, and the corrections were not what the media had aimed for.

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The experiences of grandparents raising grandchildren in Indonesia

Working with Older People ◽

10.1108/wwop-10-2018-0019 ◽

2019 ◽

Vol 23 (1) ◽

pp. 17-26

Author(s):

Rista Fauziningtyas ◽

Retno Indarwati ◽

Delisa Alfriani ◽

Joni Haryanto ◽

Elida Ulfiana ◽

...

Keyword(s):

Well Being ◽

Grandparents Raising Grandchildren ◽

Content Type ◽

Cultural Aspects ◽

Cultural Aspect ◽

Supportive Role ◽

The Family ◽

Rest Time ◽

Depth Interviews

PurposeThe raising of grandchildren by grandparents is a global phenomenon, and it is common in Indonesia. This is because parents are often unable or unwilling to raise their own children. However, the debate around “grandparenting” is still limited in Indonesia. The purpose of this paper is to gain a better understanding of the experience and views of grandparents on “grandparenting.”Design/methodology/approachThe methodology employed was qualitative and informed by phenomenology. The authors conducted in-depth interviews with 13 grandparents who were raising their grandchildren who were under five years old. The data were analyzed using thematic content analysis.Findings5 main themes and 13 subthemes emerged from the analysis of the data. The themes were responses, strategies for overcoming negative responses, the grandparents’ role, the reason for raising grandchildren, and the cultural aspect of “grandparenting” in Java. All of the grandparents enjoyed their roles as grandparents. They felt that they helped fulfill their grandchildren’s physical and educational needs.Social implicationsThe experience of raising a grandchild can be both positive and negative, depending on the cultural aspects in the Java and the family as a whole system. Grandparents require healthcare and informal support to maintain their well-being.Originality/valueThis paper provides new insights into “grandparenting” closely related to social and cultural aspect within the community. Grandparents enjoy being a part of the Javanese tradition. The supportive role of grandparents in Indonesia is important. However, older adults need to balance the role of “grandparenting” and rest time so that they remain healthy and happy.

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Explaining the success of a multinational company's innovation in the base of the pyramid: m-pesa in Kenya

Independent Journal of Management & Production ◽

10.14807/ijmp.v12i2.1311 ◽

2021 ◽

Vol 12 (2) ◽

pp. 526-556

Author(s):

Diogo Palheta Nery

Keyword(s):

Unmet Needs ◽

Adult Population ◽

First Century ◽

Base Of The Pyramid ◽

Role Of Government ◽

Supportive Role ◽

Key Points ◽

New Business ◽

In The Beginning

In the beginning of the twenty-first century, C. K. Prahalad launched a new business proposition named as “Base of the Pyramid” (BOP). In such type of business, Multinational Companies (MNCs) look for new opportunities of profits helping to meet the poor’s unmet needs in developing countries. However, MNCs significant involvement in BOP business has been losing momentum due to the challenges MNCs have been faced in developing BOP businesses. This study intended to recall Prahalad’s original BOP proposal explaining the success of a BOP innovation developed by an MNC in Kenya: M-PESA, a mobile money service. About 70% of Kenya’s adult population has M-PESA accounts and M-PESA’s monthly transactions account for 30% of Kenyan GDP. How did a multinational company develop the successful BOP innovation M-PESA in Kenya? Our study intends to explain how the British multinational Vodafone employed successful Base of the Pyramid principles of innovation in Kenyan M-PESA. Indeed, there is a gap of studies about the Prahalad’s principles of innovation for developing BOP products. Therefore, this research analyzed Prahalad’s BOP proposal, including his twelve principles of innovation to develop BOP products, by comparing such proposal with Karnani’s framework for fighting poverty. Karnani is regarded as the main critic against the Prahalad’s BOP proposal. Most of Prahalad’s BOP principles of innovation were identified in M-PESA in Kenya (eleven out of the twelve principles). However, Karnani’s framework explained better the factors that influenced successful BOP innovation in Kenyan M-PESA than Prahalad’s proposal. Furthermore, this study pointed out two key points that explained the success of M-PESA innovation in Kenya that they were not included neither in Prahalad’s nor in Karnani’s proposals: social intrapreneurship made by MNCs employees, and supportive role of government in developing BOP businesses. Therefore, such topics deserve more attention from the BOP literature in order to advance this field.

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