Genome Organisation: Human

2021 ◽  
pp. 61-71
Author(s):  
David H Kass ◽  
Mark A Batzer
Keyword(s):  
Genome Organisation

scholarly journals The Human Genome Organisation (HUGO) and the 2020 COVID-19 pandemic

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Benjamin Capps ◽  
◽  
Yann Joly ◽  
John Mulvihill ◽  
Won Bok Lee
Keyword(s):  
Human Genome ◽  
Law And Society ◽  
Genome Organisation ◽  
Global Response ◽  
Genomics Research ◽  
Human Genome Organisation ◽  
Ethics Law

AbstractThis letter is the Human Genome Organisation’s summary reaction to the 2020 COVID-19 pandemic. It identifies key areas for genomics research, and areas in which genomic scientists can contribute to a global response to the pandemic. The letter has been reviewed and endorsed by the HUGO Committee on Ethics, Law and Society (CELS) and the HUGO Council.

scholarly journals Diversity of SARS-CoV-2 isolates driven by pressure and health index

2021 ◽  
Vol 149 ◽  
Author(s):  
R. K. Sanayaima Singh ◽  
Md. Zubbair Malik ◽  
R. K. Brojen Singh
Keyword(s):  
Fractal Dimension ◽  
Severe Acute Respiratory Syndrome ◽  
Mutation Rate ◽  
Hurst Exponent ◽  
Viral Genome ◽  
Critical Pressure ◽  
Genome Organisation ◽  
Health Index ◽  
Genome Diversity ◽  
Fast Spreading

Abstract One of the main concerns about the fast spreading coronavirus disease 2019 (Covid-19) pandemic is how to intervene. We analysed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) isolates data using the multifractal approach and found a rich in viral genome diversity, which could be one of the root causes of the fast Covid-19 pandemic and is strongly affected by pressure and health index of the hosts inhabited regions. The calculated mutation rate (mr) is observed to be maximum at a particular pressure, beyond which mr maintains diversity. Hurst exponent and fractal dimension are found to be optimal at a critical pressure (Pm), whereas, for P > Pm and P < Pm, we found rich genome diversity relating to complicated genome organisation and virulence of the virus. The values of these complexity measurement parameters are found to be increased linearly with health index values.

Predicting genome organisation and function with mechanistic modelling

2021 ◽  
Author(s):  
Michael Chiang ◽  
Chris A. Brackley ◽  
Davide Marenduzzo ◽  
Nick Gilbert
Keyword(s):  
Genome Organisation ◽  
Mechanistic Modelling ◽  
And Function

scholarly journals Replication-biased genome organisation in the crenarchaeon Sulfolobus

BMC Genomics ◽  
2010 ◽  
Vol 11 (1) ◽  
pp. 454 ◽  
Author(s):  
Anders F Andersson ◽  
Erik A Pelve ◽  
Stefan Lindeberg ◽  
Magnus Lundgren ◽  
Peter Nilsson ◽  
...  
Keyword(s):  
Genome Organisation

United colours of chromatin? Developmental genome organisation in flies

2019 ◽  
Vol 47 (2) ◽  
pp. 691-700
Author(s):  
Caroline Delandre ◽  
Owen J. Marshall
Keyword(s):  
Cell Fate ◽  
Fruit Fly ◽  
Genome Organisation ◽  
Chromatin Protein ◽  
Cell Type ◽  
Chromatin States ◽  
Cell Fate Decisions ◽  
A Cell ◽  
Cell Type Specific ◽  
Chromatin Biology

Abstract The organisation of DNA into differing forms of packaging, or chromatin, controls many of the cell fate decisions during development. Although early studies focused on individual forms of chromatin, in the last decade more holistic studies have attempted to determine a complete picture of the different forms of chromatin present within a cell. In the fruit fly, Drosophila melanogaster, the study of chromatin states has been aided by the use of complementary and cell-type-specific techniques that profile the marks that recruit chromatin protein binding or the proteins themselves. Although many questions remain unanswered, a clearer picture of how different chromatin states affect development is now emerging, with more unusual chromatin states such as Black chromatin playing key roles. Here, we discuss recent findings regarding chromatin biology in flies.

Isolation and characterisation of repeated DNA sequences from Erianthus spp. (Saccharinae: Andropogoneae)

Genome ◽  
1998 ◽  
Vol 41 (3) ◽  
pp. 408-416 ◽  
Author(s):  
P Besse ◽  
C L McIntyre
Keyword(s):  
Genetic Structure ◽  
Dna Sequences ◽  
Repetitive Sequences ◽  
Intergeneric Hybrids ◽  
Genome Organisation ◽  
Repeated Dna ◽  
Saccharum Spp ◽  
Repeated Dna Sequences ◽  
Noncoding Sequences ◽  
Copy Sequence

Four anonymous noncoding sequences were isolated from Erianthus arundinaceus. The four sequences were selected because they were specific to the genusErianthus section Ripidium, relative to Saccharum spp. These sequences, designated Eracsi 294, 228, 153, and 34, showed various degrees of repetitiveness and different patterns of distribution. Eracsi 34 and 153 were low- and medium-copy repeated sequences, respectively, and appeared to be present at discrete locations in the Erianthus genome. By contrast, Eracsi 294, also a low-copy sequence, appeared to be more dispersed in location, with some tandem arrays identified. Eracsi 228 was highly repeated and dispersed. The location of Eracsi 228 was more precisely determined by FISH and was found to be distributed along the length of, but not at the telomeres of, most chromosomes in two Erianthus species. The distribution of the four sequences was investigated in a sample of 65 Erianthus (representing 9 species) and 14 Saccharum (2 species) accessions. The usefulness of these sequences for phylogenetic and genome organisation studies in sugarcane and for assessing the genetic structure of Saccharum x Erianthus intergeneric hybrids is discussed.Key words: Erianthus, FISH, repetitive sequences, Saccharum, sugarcane.

Sign in / Sign up

Export Citation Format

Share Document