Co-sensitization and cross-reactivity between related and unrelated food allergens in dogs - a serological study

Author(s):  
Jennifer Bexley ◽  
Timothy J. Nuttall ◽  
Bruce Hammerberg ◽  
Richard E. Halliwell
2016 ◽  
Vol 28 (1) ◽  
pp. 31-e7 ◽  
Author(s):  
Jennifer Bexley ◽  
Timothy J. Nuttall ◽  
Bruce Hammerberg ◽  
Richard E. Halliwell

2020 ◽  
Vol 2 (1) ◽  
pp. 17-21
Author(s):  
Olivia L. Francis ◽  
Kathleen Y. Wang ◽  
Edwin H. Kim ◽  
Timothy P. Moran

The most clinically relevant food allergens are cow’s milk, hen’s egg, peanut, tree nuts, wheat, soy, fish, shellfish, and seeds. Heat-stable food allergens have molecular characteristics that enhance protein stability and gastrointestinal absorption and thus are more likely to cause systemic reactions on ingestion. In contrast, heat-labile food allergens lack these characteristics and do not typically elicit reactions if sufficiently altered by heat or acid. Immunologic cross-sensitization between food allergens is more common than clinical cross-reactivity. However, certain groups of food allergens, such as tree nuts, fish, and shellfish, are associated with high rates of clinical cross-reactivity. Knowing the rates of clinical cross-reactivity is important when providing guidance to patients with food allergy and families on what foods can be safely added to the diet and what foods should be avoided.


1994 ◽  
Vol 15 (4) ◽  
pp. 211-216 ◽  
Author(s):  
Viswanath P. Kurup ◽  
Tracy Kelly ◽  
Nancy Elms ◽  
Kevin Kelly ◽  
Jordan Fink

2013 ◽  
Vol 6 ◽  
pp. P139
Author(s):  
Miho Hasegawa ◽  
Takatsugu Komata ◽  
Kiyotake Ogura ◽  
Katsuhito Iikura ◽  
Sakura Sato ◽  
...  

2013 ◽  
Vol 144 (5) ◽  
pp. S-494-S-495
Author(s):  
Bram D. van Rhijn ◽  
Ronald van Ree ◽  
Serge A. Versteeg ◽  
Berber J. Vlieg-Boerstra ◽  
Aline B. Sprikkelman ◽  
...  

2006 ◽  
Vol 964 (1) ◽  
pp. 47-68 ◽  
Author(s):  
STEFAN VIETHS ◽  
STEPHAN SCHEURER ◽  
BARBARA BALLMER-WEBER

2013 ◽  
Vol 61 (25) ◽  
pp. 6102-6112 ◽  
Author(s):  
Joyce Irene Boye ◽  
Allaoua Achouri ◽  
Nancy Raymond ◽  
Chantal Cleroux ◽  
Dorcas Weber ◽  
...  

2018 ◽  
Vol 20 (4) ◽  
pp. 109-115
Author(s):  
Shiva Raj KC ◽  
G. KC ◽  
P. Gyawali

Introduction: Any adverse effect on health resulting from repeated exposure to a substance against which the individual has been sensitized against is allergy. Food allergens are one of the many common causes of allergies. The aim of this study is to find out the common food allergens and also specify the type of food suspicious for allergy among the patients with allergic reactions. A total of 178 patients with allergic reactions were included. The test was carried out using kit with an enzyme-labelled antihuman IgE catalysing a colour reaction. The kit contains test stripes coated with 21 different common antigens. Concentration of antibody specific to certain allergen is calculated and graded into different classes. Among the patients sensitized to allergic food, mean age was 34.36 years with female to male ratio of 2.9:1. Ninty two patients (51.7%) patients were sensitized to 1 to 3 allergens, whereas, 3.9% w ere sensitized to more than 10 food allergens. Thirty three (27.9%) patients had definite antibody detection, 11(9.3%) patients had strong antibody titre and 4 (3.3%) patients had very high antibody titre. Most common food allergen was crab (20.1%) followed by potato (25.8%). Cross reactivity was seen in various food allergens. Cereals and rice showed significant reactivity (P <0.001). Other food like soybean with mustard, peanut with coconut and apple with grape also showed significant correlation (P<0.001). The most common food allergens were crab, potato, spinach, peanut, coconut, soybean, mustard, wheat, rice, shrimp/prawn, cucumber and onion. While determining the specific allergen, we should be aware of potential cross-reactivity against one or more food allergens.


Genes ◽  
2019 ◽  
Vol 10 (3) ◽  
pp. 234 ◽  
Author(s):  
Jessica Frigerio ◽  
Roberta Pellesi ◽  
Valerio Mezzasalma ◽  
Fabrizio De Mattia ◽  
Andrea Galimberti ◽  
...  

The spread of food allergens is a topic of global importance due to its impact on public health. National and International regulations ask food producers and manufacturers to declare product compositions on the label, especially in case of processed raw materials. Wheat flour (Triticum aestivum) can be contaminated by a wide range of species belonging to the Brassicaceae in the field or during grain harvests, storage, and processing. Among them, mustards (Brassica nigra, Brassica juncea and Sinapis alba) are well known allergenic species. Often, food quality laboratories adopt an ELISA approach to detect the presence of mustard species. However, this approach shows cross-reactivity with other non-allergenic species such as Brassica napus (rapeseed). In the last few years, DNA barcoding was proposed as a valid identification method, and it is now commonly used in the authentication of food products. This study aims to set up an easy and rapid DNA-based tool to detect mustard allergenic species. DNA barcoding (matK and ITS2) and chromosome markers (A6, B, C1 genome regions) were selected, and specific primers were validated on incurred reference food matrices. The developed test was proven to be able to distinguish mustard from rapeseed and wheat, overcoming cross-reactivity with Brassica napus.


2005 ◽  
Vol 116 (1) ◽  
pp. 213-219 ◽  
Author(s):  
Beatrice Jahn-Schmid ◽  
Astrid Radakovics ◽  
Dirk Lüttkopf ◽  
Stephan Scheurer ◽  
Stefan Vieths ◽  
...  

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