Vergleich von Blutfluß und Benzodiazepin-Rezeptorverteilung bei fokaler Epilepsie: Vorläufige Ergebnisse einer SPECT-Studie

1989 ◽  
Vol 28 (05) ◽  
pp. 181-186
Author(s):  
A. Ludolph ◽  
O. Schober ◽  
G. Lottes ◽  
I. Böttger ◽  
H.-F. Beer ◽  
...  
Keyword(s):  
Human Brain ◽  
Receptor Binding ◽  
Brain Area ◽  
Brain Perfusion ◽  
Partial Epilepsy ◽  
Cerebral Lesion ◽  
Receptor Ligand ◽  
Receptor Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

Nano-Mechanics and Membrane Receptor Mapping of CD8 + T Cells (Supplementry Material)

2009 ◽  
Vol 5 (4) ◽  
pp. 465-469
Author(s):  
Yangzhe Wu ◽  
Yi Hu ◽  
Hongsong Lu ◽  
Jiye Cai ◽  
Xianhui He ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Membrane Receptor ◽  
Receptor Mapping

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

1988 ◽  
Vol 31 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Marcel F. Hibert ◽  
Maurice W. Gittos ◽  
Derek N. Middlemiss ◽  
Anis K. Mir ◽  
John R. Fozard
Keyword(s):  
Drug Design ◽  
Design Development ◽  
Predictive Tool ◽  
Receptor Mapping ◽  
Computer Aided

Receptor Mapping by Histochemistry

1982 ◽  
pp. 27-51
Author(s):  
James K. Wamsley ◽  
Jose M. Palacios
Keyword(s):  
Receptor Mapping

Conformational Analysis of D1Dopamine Receptor Agonists:  Pharmacophore Assessment and Receptor Mapping†

1996 ◽  
Vol 39 (1) ◽  
pp. 285-296 ◽  
Author(s):  
David M. Mottola ◽  
Sergei Laiter ◽  
Val J. Watts ◽  
Alexander Tropsha ◽  
Steven D. Wyrick ◽  
...  
Keyword(s):  
Conformational Analysis ◽  
Receptor Agonists ◽  
Receptor Mapping

scholarly journals Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition

Immunity ◽  
1998 ◽  
Vol 8 (4) ◽  
pp. 413-425 ◽  
Author(s):  
Thomas C Manning ◽  
Carol J Schlueter ◽  
Thomas C Brodnicki ◽  
Evan A Parke ◽  
Jeffrey A Speir ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Antigen Recognition ◽  
Alanine Scanning Mutagenesis ◽  
Alanine Scanning ◽  
Receptor Mapping
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