3D printed polyurethane tissue engineering scaffold with hierarchical microcellular foam structure and antibacterial properties

2022 ◽  
Author(s):  
Shuai Zhang ◽  
Xuetao Shi ◽  
Zhenyun Miao ◽  
Haibin Zhang ◽  
Xin Zhao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Antibacterial Properties ◽  
Tissue Engineering Scaffold ◽  
Microcellular Foam ◽  
Foam Structure ◽  
3D Printed

scholarly journals Three-Dimensional Printing of Hydroxyapatite Composites for Biomedical Application

Crystals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 353
Author(s):  
Yanting Han ◽  
Qianqian Wei ◽  
Pengbo Chang ◽  
Kehui Hu ◽  
Oseweuba Valentine Okoro ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Biomedical Application ◽  
Three Dimensional ◽  
Antibacterial Properties ◽  
Natural Polymers ◽  
Three Dimensional Printing ◽  
3D Printed ◽  
Dental Applications ◽  
Hard Tissue Engineering

Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite. However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields. In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds. This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites. In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed. Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored. Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussed.

scholarly journals Study on antibacterial properties and cytocompatibility of EPL coated 3D printed PCL/HA composite scaffolds

RSC Advances ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 4805-4816 ◽  
Author(s):  
Lijiao Tian ◽  
Zhenting Zhang ◽  
Bin Tian ◽  
Xin Zhang ◽  
Na Wang
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Critical Role ◽  
Antibacterial Properties ◽  
Composite Scaffolds ◽  
Biomaterial Scaffolds ◽  
3D Printed

Biomaterial scaffolds play a critical role in bone tissue engineering.

Performance of 3D printed PCL / PLGA / HA biological bone tissue engineering scaffold

2021 ◽  
Author(s):  
Zhiyong Ma ◽  
Qifan Wang ◽  
Wenjia Xie ◽  
Wenjie Ye ◽  
Linna Zhong ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tissue Engineering Scaffold ◽  
3D Printed

scholarly journals 3D printed dual macro-, microscale porous network as a tissue engineering scaffold with drug delivering function

2019 ◽  
Vol 11 (3) ◽  
pp. 035014 ◽  
Author(s):  
Hoang Phuc Dang ◽  
Tara Shabab ◽  
Abbas Shafiee ◽  
Quentin C Peiffer ◽  
Kate Fox ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Tissue Engineering Scaffold ◽  
Porous Network ◽  
3D Printed

Biomimetic Design of 3D Printed Tissue-engineered bone Constructs

2020 ◽  
Vol 16 ◽  
Author(s):  
Wei Liu ◽  
Shifeng Liu ◽  
Yunzhe Li ◽  
Peng Zhou ◽  
Qian ma
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Advanced Materials ◽  
Bionic Design ◽  
Material Interfaces ◽  
Precise Control ◽  
Cell Printing ◽  
Biomimetic Scaffolds ◽  
3D Printed

Abstract:: Surgery to repair damaged tissue, which is caused by disease or trauma, is being carried out all the time, and a desirable treatment is compelling need to regenerate damaged tissues to further improve the quality of human health. Therefore, more and more research focus on exploring the most suitable bionic design to enrich available treatment methods. 3D-printing, as an advanced materials processing approach, holds promising potential to create prototypes with complex constructs that could reproduce primitive tissues and organs as much as possible or provide appropriate cell-material interfaces. In a sense, 3D printing promises to bridge between tissue engineering and bionic design, which can provide an unprecedented personalized recapitulation with biomimetic function under the precise control of the composition and spatial distribution of cells and biomaterials. This article describes recent progress in 3D bionic design and the potential application prospect of 3D printing regenerative medicine including 3D printing biomimetic scaffolds and 3D cell printing in tissue engineering.

scholarly journals Recycled algae-based carbon materials as electroconductive 3D printed skeletal muscle tissue engineering scaffolds

2021 ◽  
Vol 32 (7) ◽  
Author(s):  
Selva Bilge ◽  
Emre Ergene ◽  
Ebru Talak ◽  
Seyda Gokyer ◽  
Yusuf Osman Donar ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Tissue Engineering ◽  
Electrical Stimulation ◽  
Muscle Tissue ◽  
Carbonaceous Material ◽  
Hydrothermal Carbonization ◽  
Skeletal Muscle Tissue ◽  
Myotube Formation ◽  
3D Printed

AbstractSkeletal muscle is an electrically and mechanically active tissue that contains highly oriented, densely packed myofibrils. The tissue has self-regeneration capacity upon injury, which is limited in the cases of volumetric muscle loss. Several regenerative therapies have been developed in order to enhance this capacity, as well as to structurally and mechanically support the defect site during regeneration. Among them, biomimetic approaches that recapitulate the native microenvironment of the tissue in terms of parallel-aligned structure and biophysical signals were shown to be effective. In this study, we have developed 3D printed aligned and electrically active scaffolds in which the electrical conductivity was provided by carbonaceous material (CM) derived from algae-based biomass. The synthesis of this conductive and functional CM consisted of eco-friendly synthesis procedure such as pre-carbonization and multi-walled carbon nanotube (MWCNT) catalysis. CM obtained from biomass via hydrothermal carbonization (CM-03) and its ash form (CM-03K) were doped within poly(ɛ-caprolactone) (PCL) matrix and 3D printed to form scaffolds with aligned fibers for structural biomimicry. Scaffolds were seeded with C2C12 mouse myoblasts and subjected to electrical stimulation during the in vitro culture. Enhanced myotube formation was observed in electroactive groups compared to their non-conductive counterparts and it was observed that myotube formation and myotube maturity were significantly increased for CM-03 group after electrical stimulation. The results have therefore showed that the CM obtained from macroalgae biomass is a promising novel source for the production of the electrically conductive scaffolds for skeletal muscle tissue engineering.

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