Gold Nanorods Electrostatically Binding Nucleic Acid Probe for In Vivo MicroRNA Amplified Detection and Photoacoustic Imaging-Guided Photothermal Therapy

2018 ◽  
Vol 28 (22) ◽  
pp. 1800490 ◽  
Author(s):  
Nan Yan ◽  
Xiaojing Wang ◽  
Lin Lin ◽  
Tingjie Song ◽  
Pingjie Sun ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging

Core-Shell Pd@Au Nanoplates as Theranostic Agents for In-Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ct Imaging ◽  
Core Shell ◽  
Theranostic Agents

In vivo clearable inorganic nanophotonic materials: designs, materials and applications

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12742-12754 ◽  
Author(s):  
Jianmin Nie ◽  
Yang Li ◽  
Gang Han ◽  
Jianrong Qiu
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Therapeutic Agents ◽  
Bio Imaging

Inorganic nanophotonic materials (INPMs) are considered to be promising diagnosis and therapeutic agents for in vivo applications, such as bio-imaging, photoacoustic imaging and photothermal therapy.

A simple POM clusters for in vivo NIR-II photoacoustic imaging-guided NIR-II photothermal therapy

2020 ◽  
Vol 209 ◽  
pp. 111121 ◽  
Author(s):  
Yahong Han ◽  
Botao Qu ◽  
Juan Li ◽  
Xiaomin Zhang ◽  
Xiaoyang Peng ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging

A portable device with low-power consumption for monitoring mouse vital signs during in vivo photoacoustic imaging and photothermal therapy

2021 ◽  
Vol 41 (12) ◽  
pp. 125011
Author(s):  
Duc Tri Phan ◽  
Thi Tuong Vy Phan ◽  
Ngoc Thang Bui ◽  
Sumin Park ◽  
Jaeyeop Choi ◽  
...  
Keyword(s):  
Power Consumption ◽  
Low Power ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Vital Signs ◽  
Portable Device ◽  
Low Power Consumption

In vivo photoacoustic imaging with multiple selective targeting using bioconjugated gold nanorods

2008 ◽  
Author(s):  
Chen-Wei Wei ◽  
Chao-Kang Liao ◽  
Ying-Yi Chen ◽  
Churng-Ren Chris Wang ◽  
Ann-Ann Ding ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Photoacoustic Imaging ◽  
Selective Targeting

scholarly journals Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice

2017 ◽  
Vol 114 (15) ◽  
pp. E3110-E3118 ◽  
Author(s):  
Moustafa R. K. Ali ◽  
Mohammad Aminur Rahman ◽  
Yue Wu ◽  
Tiegang Han ◽  
Xianghong Peng ◽  
...  
Keyword(s):  
Cell Death ◽  
Mechanism Of Action ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Mouse Tumor ◽  
Maximal Induction

Gold nanorods (AuNRs)-assisted plasmonic photothermal therapy (AuNRs-PPTT) is a promising strategy for combating cancer in which AuNRs absorb near-infrared light and convert it into heat, causing cell death mainly by apoptosis and/or necrosis. Developing a valid PPTT that induces cancer cell apoptosis and avoids necrosis in vivo and exploring its molecular mechanism of action is of great importance. Furthermore, assessment of the long-term fate of the AuNRs after treatment is critical for clinical use. We first optimized the size, surface modification [rifampicin (RF) conjugation], and concentration (2.5 nM) of AuNRs and the PPTT laser power (2 W/cm2) to achieve maximal induction of apoptosis. Second, we studied the potential mechanism of action of AuNRs-PPTT using quantitative proteomic analysis in mouse tumor tissues. Several death pathways were identified, mainly involving apoptosis and cell death by releasing neutrophil extracellular traps (NETs) (NETosis), which were more obvious upon PPTT using RF-conjugated AuNRs (AuNRs@RF) than with polyethylene glycol thiol-conjugated AuNRs. Cytochrome c and p53-related apoptosis mechanisms were identified as contributing to the enhanced effect of PPTT with AuNRs@RF. Furthermore, Pin1 and IL18-related signaling contributed to the observed perturbation of the NETosis pathway by PPTT with AuNRs@RF. Third, we report a 15-month toxicity study that showed no long-term toxicity of AuNRs in vivo. Together, these data demonstrate that our AuNRs-PPTT platform is effective and safe for cancer therapy in mouse models. These findings provide a strong framework for the translation of PPTT to the clinic.

scholarly journals Photothermal Therapy: pH-Responsive Fe(III)-Gallic Acid Nanoparticles for In Vivo Photoacoustic-Imaging-Guided Photothermal Therapy (Adv. Healthcare Mater. 7/2016)

2016 ◽  
Vol 5 (7) ◽  
pp. 745-745 ◽  
Author(s):  
Jianfeng Zeng ◽  
Ming Cheng ◽  
Yong Wang ◽  
Ling Wen ◽  
Ling Chen ◽  
...  
Keyword(s):  
Gallic Acid ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ph Responsive

Multifunctional Cu–Ag2S nanoparticles with high photothermal conversion efficiency for photoacoustic imaging-guided photothermal therapy in vivo

Nanoscale ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 825-831 ◽  
Author(s):  
Lile Dong ◽  
Guanming Ji ◽  
Yu Liu ◽  
Xia Xu ◽  
Pengpeng Lei ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
The Novel ◽  
Photothermal Conversion ◽  
Ag2s Nanoparticles

The novel Cu–Ag2S/PVP NPs with high photothermal conversion efficiency could be employed as effective photoacoustic imaging guided photothermal therapy agents.

Ultrasound and photoacoustic image-guided photothermal therapy using silica-coated gold nanorods: In-vivo study

2010 ◽  
Author(s):  
Seungsoo Kim ◽  
Yun-Sheng Chen ◽  
Geoffrey P. Luke ◽  
Mohammad Mehrmohammadi ◽  
Jason R. Cook ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Photothermal Therapy ◽  
In Vivo Study ◽  
Image Guided
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