High‐Resolution 3D NIR‐II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent

2019 ◽  
Vol 31 (25) ◽  
pp. 1808355 ◽  
Author(s):  
Bing Guo ◽  
Jingqin Chen ◽  
Ningbo Chen ◽  
Eshu Middha ◽  
Shidang Xu ◽  
...  
Keyword(s):  
High Resolution ◽  
Contrast Agent ◽  
Conjugated Polymer ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles

Hydrogen peroxide degradable conjugated polymer nanoparticles for fluorescence and photoacoustic bimodal imaging

2018 ◽  
Vol 54 (20) ◽  
pp. 2518-2521 ◽  
Author(s):  
Jie Liu ◽  
Shaowei Wang ◽  
Xiaolei Cai ◽  
Shiwei Zhou ◽  
Bin Liu
Keyword(s):  
Hydrogen Peroxide ◽  
Contrast Agent ◽  
Conjugated Polymer ◽  
Cellular Imaging ◽  
Polymer Nanoparticles ◽  
Dual Modality ◽  
Bimodal Imaging ◽  
Conjugated Polymer Nanoparticles

A hydrogen peroxide degradable fluorescence/photoacoustic dual-modality contrast agent is prepared via in situ Sonogashira polymerization for cellular imaging.

scholarly journals Multifunctional conjugated polymer nanoparticles for photoacoustic-based multimodal imaging and cancer photothermal therapy

2019 ◽  
Vol 12 (03) ◽  
pp. 1930001 ◽  
Author(s):  
Xiaoju Men ◽  
Zhen Yuan
Keyword(s):  
Conjugated Polymer ◽  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Photoacoustic Imaging ◽  
Biological Tissues ◽  
Polymer Nanoparticles ◽  
Imaging Method ◽  
Conjugated Polymer Nanoparticles ◽  
Good Biocompatibility ◽  
Cancer Theranostics

Photoacoustic imaging (PAI) is a hybrid imaging method based on photoacoustic (PA) effects, which is able to capture the structure, function, and molecular information of biological tissues with high resolution. To date, therapeutic techniques under the guidance of PAI have provided new strategies for accurate diagnosis and precise treatment of tumors. In particular, conjugated polymer nanoparticles have been extensively inspected for PA-based cancer theranostics largely due to their superior optical properties such as tunable spectrum and large absorption coefficient and their good biocompatibility, and abundant functional groups. This mini-review mainly focuses on the recent advances toward the development of novel conjugated polymer nanoparticles for PA-based multimodal imaging and cancer photothermal therapy.

Molecular engineering of diketopyrrolopyrrole-conjugated polymer nanoparticles by chalcogenide variation for photoacoustic imaging guided photothermal therapy

2021 ◽  
Vol 9 (14) ◽  
pp. 3153-3160
Author(s):  
Xin Jin ◽  
Xiaoyi Xing ◽  
Qingyuan Deng ◽  
Weixia Qing ◽  
Zhonghua Liu ◽  
...  
Keyword(s):  
Conjugated Polymers ◽  
Efficient Method ◽  
Conjugated Polymer ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Molecular Engineering ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles ◽  
Molecular Skeleton

This work presents an efficient method of accessing DPP-SO that not only possess an excellent anti-tumour property but also regulates the photothermal performance of DPP-conjugated polymers by changing the heteroatom in the molecular skeleton.

scholarly journals Conjugated polymers as nanoparticle probes for fluorescence and photoacoustic imaging

2020 ◽  
Vol 8 (4) ◽  
pp. 592-606 ◽  
Author(s):  
Thais Fedatto Abelha ◽  
Cécile A. Dreiss ◽  
Mark A. Green ◽  
Lea Ann Dailey
Keyword(s):  
Conjugated Polymers ◽  
Conjugated Polymer ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
Nanoparticle Probes ◽  
Conjugated Polymer Nanoparticles

In this review, the role of conjugated polymer nanoparticles (CPNs) in emerging bioimaging techniques is described.

Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window

2017 ◽  
Vol 4 (6) ◽  
pp. 1151-1156 ◽  
Author(s):  
Bing Guo ◽  
Zonghai Sheng ◽  
Kenry Kenry ◽  
Dehong Hu ◽  
Xiangwei Lin ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
High Signal ◽  
Highly Efficient ◽  
Conjugated Polymer Nanoparticles ◽  
Good Penetration ◽  
Good Biocompatibility

NIR II conjugated polymer nanoparticles with good biocompatibility, excellent photoacoustic stability and high imaging contrast are formulated, which allows highly efficient imaging of orthotopic brain tumors with a high signal/background ratio and a good penetration depth.

Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models

ACS Nano ◽  
2015 ◽  
Vol 9 (5) ◽  
pp. 5275-5288 ◽  
Author(s):  
Ruslan I. Dmitriev ◽  
Sergey M. Borisov ◽  
Heiko Düssmann ◽  
Shiwen Sun ◽  
Bernhard J. Müller ◽  
...  
Keyword(s):  
High Resolution ◽  
Conjugated Polymer ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles ◽  
Tissue Models ◽  
In Cells

Bis-diketopyrrolopyrrole conjugated polymer nanoparticles as photothermic nanoagonist for specific and synergistic glioblastoma therapy

Biomaterials ◽  
2019 ◽  
Vol 216 ◽  
pp. 119252 ◽  
Author(s):  
Shengliang Li ◽  
Qingyuan Deng ◽  
Xiao Li ◽  
Yongwei Huang ◽  
Xiaozhen Li ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Polymer Nanoparticles ◽  
Conjugated Polymer Nanoparticles
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