Digital mobility outcomes to assess habitual physical activity in people with cognitive impairment: A systematic review

Age-related dementia refers to a state in which someone experiences multiple cognitive function impairment due to degenerative brain disease, and which causes difficulties in their daily life or social life. Dementia is the most common and serious obstacle in later life. Early intervention in the case of patients who are in the mild cognitive impairment (MCI) stage among the high-risk group can maintain and improve their cognitive function. The purpose of the current trial is aimed at investigating the association between a multi-component (exercise with cognitive) intervention program and habitual physical activity parameters on cognitive functions in MCI patients. Neuropsychological cognitive and depression assessments were performed by neuropsychologists according to normalized methods, including the Korean mini-mental State examination (K-MMSE) and modified Alzheimer’s disease assessment scale-cognitive subscale (ADAS-Cog) and cognitive assessment tool (attention, processing speed), and the Korean version of the geriatric depression scale (SGDS-K), both at baseline and at a 12 weeks follow-up. The 12-week multi-component intervention improved cognitive function and habitual physical activity parameters in patients with MCI relative to controls. A multi-component intervention program for patients with MCI is considered to be an effective method of dementia prevention by improving global (ADAS-Cog) and frontal (trail-making test, digit symbol substitution test) cognition and habitual physical activity parameters such as moderate to vigorous physical activity and step count. In addition, it is important to encourage habitual physical activities to ensure that exercise intervention strategies are carried out at the duration and intensity required for improving physical and cognitive wellbeing and obtaining health benefits.

Download Full-text

Habitual physical activity can be increased in people with cerebral palsy: a systematic review

Clinical Rehabilitation ◽

10.1177/0269215510383062 ◽

2010 ◽

Vol 25 (4) ◽

pp. 303-315 ◽

Cited By ~ 17

Author(s):

Theofani Bania ◽

Karen J Dodd ◽

Nicholas Taylor

Keyword(s):

Physical Activity ◽

Systematic Review ◽

Cerebral Palsy ◽

Habitual Physical Activity

Download Full-text

The impact of physical activity on blood inflammatory cytokines and neuroprotective factors in individuals with mild cognitive impairment: a systematic review and meta-analysis of randomized-controlled trials

Aging Clinical and Experimental Research ◽

10.1007/s40520-021-02069-6 ◽

2022 ◽

Author(s):

Chuyi Ma ◽

Miaoran Lin ◽

Jiahui Gao ◽

Shurui Xu ◽

Li Huang ◽

...

Keyword(s):

Physical Activity ◽

Systematic Review ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Randomized Controlled Trials ◽

Inflammatory Cytokines ◽

Meta Analysis ◽

Controlled Trials ◽

Randomized Controlled ◽

The Impact

Download Full-text

The role of habitual physical activity on arterial stiffness in elderly Individuals: a systematic review and meta-analysis

The Journal of Exercise Nutrition and Biochemistry ◽

10.20463/jenb.2017.0041 ◽

2017 ◽

Vol 21 (4) ◽

pp. 16-21 ◽

Cited By ~ 6

Author(s):

Wonil Park ◽

Hun-Young Park ◽

Kiwon Lim ◽

Jonghoon Park

Keyword(s):

Physical Activity ◽

Systematic Review ◽

Arterial Stiffness ◽

Meta Analysis ◽

Habitual Physical Activity ◽

Elderly Individuals

Download Full-text

Exploring Cognitively Loaded Physical Activity Compared With Control to Improve Global Cognitive Function in Older Community-Dwelling Adults With Mild Cognitive Impairment: Systematic Review With Meta-Analysis

American Journal of Lifestyle Medicine ◽

10.1177/1559827619876887 ◽

2019 ◽

pp. 155982761987688

Author(s):

Kristina Zawaly ◽

Richard Fortier ◽

Stephen Buetow ◽

Lynette Tippett ◽

Ngaire Kerse

Keyword(s):

Physical Activity ◽

Systematic Review ◽

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Meta Analysis ◽

Community Dwelling ◽

Controlled Trials ◽

Global Cognitive Function ◽

Global Cognition

Objective. A systematic review with a meta-analysis explored effects of cognitively loaded physical activity interventions on global cognition in community-dwelling older adults (≥65 years of age) experiencing mild cognitive impairment (MCI), compared to any control. Methods. A literature search was conducted in 4 databases (MEDLINE [OvidSP], PubMed, CINAHL, and the Cochrane Central Register of Controlled Trials [Wiley]) from inception until January 30, 2018. The meta-analysis was conducted with Review Manager 5.3. Results. Six randomized controlled trials (RCTs) with 547 participants were identified. The interventions ranged from 4 to 52 weeks. Baseline and initial follow-up assessments were used. The primary pooled analysis of all RCTs demonstrated a nonsignificant trivial effect (standardized mean difference [SMD] 0.07, 95% confidence interval [CI] −0.44 to 0.58) favoring the intervention. In pooled subanalysis of 4 RCTs (n = 405) using the same global cognition measure (Mini-Mental State Examination) and duration of intervention >12 weeks, the intervention group achieved a small but significant improvement for global cognition (SMD 0.45, 95% CI 0.14 to 0.75). Conclusion. When all the RCTs were pooled, the effect of cognitively loaded physical activity intervention on global cognitive function in older adults with MCI remained unclear. The subgroup analysis provides translation evidence for future RCT study designs.

Download Full-text