Abstract
Introduction There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa.Objective To estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda.Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia.Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p˂0.001), having some education (AOR, 0.57; 95% CI, 0.41-0.81, p=0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p=0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p=0.001).Conclusion In this population-based sample of older-age adults, nearly one-fifth screened positive for dementia.
Alzheimer's disease clinical onset and age at death in people with Down syndrome: A systematic review and population‐based study
