A smartphone‐based self‐administered test of verbal episodic memory: Development and initial validation

Abstract Sociocultural developmental psychology can drive new directions in gadgetry science. We use autobiographical memory, a compound capacity incorporating episodic memory, as a case study. Autobiographical memory emerges late in development, supported by interactions with parents. Intervention research highlights the causal influence of these interactions, whereas cross-cultural research demonstrates culturally determined diversity. Different patterns of inheritance are discussed.

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Inflammatory Markers May Inform the Effects of Electroconvulsive Therapy on Cognition in Patients with Depression

Neuropsychobiology ◽

10.1159/000515931 ◽

2021 ◽

pp. 1-9

Author(s):

Jan-Baptist Belge ◽

Linda Van Diermen ◽

Bernard Sabbe ◽

Manuel Morrens ◽

Violette Coppens ◽

...

Keyword(s):

Episodic Memory ◽

Cognitive Functioning ◽

Electroconvulsive Therapy ◽

Inflammatory Markers ◽

Verbal Learning ◽

Potential Biomarker ◽

Tnf Α ◽

Autobiographic Memory ◽

Learning Test ◽

Verbal Episodic Memory

Introduction: The neurobiological mechanisms underlying the acute cognitive effects of electroconvulsive therapy (ECT) remain poorly understood. Prior research has shown that proinflammatory cytokines such as IL-6, TNF-α, IL1-β, and IL-10 may interfere with cognitive functioning. Interestingly, immunomodulation is one of the proposed modes of action of ECT. This study investigates whether changes of peripheral levels of IL-6, TNF-α, IL1-β, and IL-10 are related to changes in cognitive functioning following ECT. Methods: In the week before and 1 week after an acute course of ECT, 62 patients suffering from depression underwent a neuropsychological evaluation to assess their processing speed using the Symbol Digit Substitution Test (SDST), verbal episodic memory using the Hopkins Verbal Learning Test-Revised (HVLT-R), and their retrospective autobiographic memory using the Autobiographical Memory Interview (AMI) with the peripheral inflammatory markers being measured at the same 2 time points. Results: Patients improved drastically following ECT, while their main performance on both the HVLT-R and AMI declined and their SDST scores remained stable. The levels of IL-6 and IL1-β had both decreased, where the decrease in IL-6 was related to the decrease in HVLT-R scores. Higher baseline IL-10 levels were associated with a more limited decrease of the HVLT-R scores. Conclusion: Our findings tentatively suggest that the effects of ECT on verbal episodic memory may be related to the treatment’s immunomodulatory properties, most notably due to decreased IL-6 levels. Moreover, baseline IL-10 appears to be a potential biomarker to predict the effects of ECT on verbal episodic memory. Whilst compelling, the results of this study should be interpreted with caution as, due to its exploratory nature, no correction for multiple comparisons was made. Further, a replication in larger cohorts is warranted.

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Effect of Anserine/Carnosine Supplementation on Verbal Episodic Memory in Elderly People

Journal of Alzheimer s Disease ◽

10.3233/jad-150767 ◽

2015 ◽

Vol 50 (1) ◽

pp. 149-159 ◽

Cited By ~ 38

Author(s):

Tatsuhiro Hisatsune ◽

Jun Kaneko ◽

Hiroki Kurashige ◽

Yuan Cao ◽

Hideo Satsu ◽

...

Keyword(s):

Episodic Memory ◽

Elderly People ◽

Verbal Episodic Memory

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P1-392: Comparison of verbal episodic memory measures: Consortium to establish a registry for Alzheimer's disease - neuropsychological assessment battery (CERAD-NAB) vs. California verbal learning test (CVLT)

Alzheimer s & Dementia ◽

10.1016/j.jalz.2011.05.673 ◽

2011 ◽

Vol 7 ◽

pp. S238-S238

Author(s):

Irene Beck ◽

Alexa Gagneux ◽

Manfred Berres ◽

Andreas Monsch

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Episodic Memory ◽

Neuropsychological Assessment ◽

Verbal Learning ◽

California Verbal Learning Test ◽

Assessment Battery ◽

Learning Test ◽

Neuropsychological Assessment Battery ◽

Verbal Episodic Memory

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Compensatory reallocation of brain resources supporting verbal episodic memory in Alzheimer's disease

Neurology ◽

10.1212/wnl.46.3.692 ◽

1996 ◽

Vol 46 (3) ◽

pp. 692-700 ◽

Cited By ~ 142

Author(s):

J. T. Becker ◽

M. A. Mintun ◽

K. Aleva ◽

M. B. Wiseman ◽

T. Nichols ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Episodic Memory ◽

Verbal Episodic Memory

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Predictions of verbal episodic memory in persons with Alzheimer's disease

Journal of Clinical and Experimental Neuropsychology ◽

10.1080/13803395.2010.507184 ◽

2010 ◽

Vol 33 (2) ◽

pp. 218-225 ◽

Cited By ~ 10

Author(s):

Maureen Schmitter-Edgecombe ◽

Adriana M. Seelye

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Episodic Memory ◽

Verbal Episodic Memory

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Validity of the Five-Word Test for the Evaluation of Verbal Episodic Memory and Dementia in a Memory Clinic Setting

Journal of Geriatric Psychiatry and Neurology ◽

10.1177/0891988712445088 ◽

2012 ◽

Vol 25 (2) ◽

pp. 78-84 ◽

Cited By ~ 13

Author(s):

Eric Mormont ◽

Jacques Jamart ◽

Laurence Robaye

Keyword(s):

Episodic Memory ◽

Memory Clinic ◽

Word Test ◽

Clinic Setting ◽

Verbal Episodic Memory

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Intraindividual Variability in Domain-Specific Cognition and Risk of Mild Cognitive Impairment and Dementia

Current Gerontology and Geriatrics Research ◽

10.1155/2013/495793 ◽

2013 ◽

Vol 2013 ◽

pp. 1-10 ◽

Cited By ~ 17

Author(s):

Leslie Vaughan ◽

Iris Leng ◽

Dale Dagenbach ◽

Susan M. Resnick ◽

Stephen R. Rapp ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Episodic Memory ◽

Proportional Hazards ◽

Intraindividual Variability ◽

Adult Women ◽

Interindividual Differences ◽

Cognitive Domains ◽

Domain Specific ◽

Verbal Episodic Memory

Intraindividual variability among cognitive domains may predict dementia independently of interindividual differences in cognition. A multidomain cognitive battery was administered to 2305 older adult women (mean age 74 years) enrolled in an ancillary study of the Women’s Health Initiative. Women were evaluated annually for probable dementia and mild cognitive impairment (MCI) for an average of 5.3 years using a standardized protocol. Proportional hazards regression showed that lower baseline domain-specific cognitive scores significantly predicted MCI (N=74), probable dementia (N=45), and MCI or probable dementia combined (N=101) and that verbal and figural memory predicted each outcome independently of all other cognitive domains. The baseline intraindividual standard deviation across test scores (IAV Cognitive Domains) significantly predicted probable dementia and this effect was attenuated by interindividual differences in verbal episodic memory. Slope increases in IAV Cognitive Domains across measurement occasions (IAV Time) explained additional risk for MCI and MCI or probable dementia, beyond that accounted for by interindividual differences in multiple cognitive measures, but risk for probable dementia was attenuated by mean decreases in verbal episodic memory slope. These findings demonstrate that within-person variability across cognitive domains both at baseline and longitudinally independently accounts for risk of cognitive impairment and dementia in support of the predictive utility of within-person variability.

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