Solvent- and Achiral-Guest-Triggered Chiral Inversion in a Planar Chiralpseudo[1]Catenane

2013 ◽  
Vol 125 (31) ◽  
pp. 8269-8273 ◽  
Author(s):  
Tomoki Ogoshi ◽  
Tomohiro Akutsu ◽  
Daiki Yamafuji ◽  
Takamichi Aoki ◽  
Tada-aki Yamagishi
Keyword(s):  
Chiral Inversion

Triple-Modulated Chiral Inversion of Co-Assembly System Based on Alanine Amphiphile and Cyanostilbene Derivative

2021 ◽  
Author(s):  
Penghua Qin ◽  
Zhen Wu ◽  
Pengyu Li ◽  
Dian Niu ◽  
Minghua Liu ◽  
...  
Keyword(s):  
Assembly System ◽  
Chiral Inversion

scholarly journals Continuous transformation of chiral pharmaceuticals in enzymatic membrane bioreactors for advanced wastewater treatment

2017 ◽  
Vol 76 (7) ◽  
pp. 1816-1826 ◽  
Author(s):  
Luong N. Nguyen ◽  
Faisal I. Hai ◽  
James A. McDonald ◽  
Stuart J. Khan ◽  
William E. Price ◽  
...  
Keyword(s):  
Wastewater Treatment ◽  
Membrane Bioreactor ◽  
Redox Mediator ◽  
Membrane Bioreactors ◽  
Continuous Transformation ◽  
Chiral Inversion ◽  
Enantiomeric Analysis ◽  
Chiral Pharmaceuticals ◽  
Advanced Wastewater Treatment ◽  
Enzymatic Membrane

This study demonstrates continuous enantiomeric inversion and further biotransformation of chiral profens including ibuprofen, naproxen and ketoprofen by an enzymatic membrane bioreactor (EMBR) dosed with laccase. The EMBR showed non-enantioselective transformations, with high and consistent transformation of both (R)- and (S)-ibuprofen (93 ± 6%, n= 10), but lower removals of both enantiomers of naproxen (46 ± 16%, n= 10) and ketoprofen (48 ± 17%, n= 10). Enantiomeric analysis revealed a bidirectional but uneven inversion of the profens, for example 14% inversion of (R)- to (S)- compared to 4% from (S)- to (R)-naproxen. With redox-mediator addition, the enzymatic chiral inversion of both (R)- and (S)-profens remained unchanged, although the overall conversion became enantioselective; except for (S)-naproxen, the addition of redox mediator promoted the degradation of (R)-profens only.

Metabolic chiral inversion of ibuprofen in isolated rat hepatocytes

Chirality ◽  
1990 ◽  
Vol 2 (2) ◽  
pp. 74-78 ◽  
Author(s):  
Sylvia Müller ◽  
Joachim M. Mayer ◽  
Jean-Claude Etter ◽  
Bernard Testa
Keyword(s):  
Rat Hepatocytes ◽  
Chiral Inversion ◽  
Isolated Rat Hepatocytes ◽  
Isolated Rat

Reversible helical chirality of perylene bisimide aggregates: amino acid-directed chiral transfer and chiral inversion

Soft Matter ◽  
2017 ◽  
Vol 13 (17) ◽  
pp. 3072-3075 ◽  
Author(s):  
Yizhi Liu ◽  
Xinpei Gao ◽  
Fei Lu ◽  
Mei Hu ◽  
Lijuan Shi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Chiral Inversion ◽  
Perylene Bisimide ◽  
Helical Chirality
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