scholarly journals Ru(II)-based antineoplastic: A “wingtip” N-heterocyclic carbene facilitates access to a new class of organometallics that are cytotoxic to common cancer cell lines

2018 ◽  
Vol 33 (1) ◽  
pp. e4692 ◽  
Author(s):  
Ambarish Mondal ◽  
Rajat K. Tripathy ◽  
Parul Dutta ◽  
Manas Kumar Santra ◽  
Anvarhusein A. Isab ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
New Class ◽  
Common Cancer

Abstract 743: Fusion gene identification from common cancer cell lines and comparison to primary tumors

2019 ◽  
Author(s):  
Neetha Nanoth Vellichirammal ◽  
Abrar Albahrani ◽  
Jasjit K. Banwait ◽  
You Li ◽  
Babu Guda
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Fusion Gene ◽  
Cancer Cell Lines ◽  
Gene Identification ◽  
Primary Tumors ◽  
Common Cancer

Abstract 743: Fusion gene identification from common cancer cell lines and comparison to primary tumors

2019 ◽  
Author(s):  
Neetha Nanoth Vellichirammal ◽  
Abrar Albahrani ◽  
Jasjit K. Banwait ◽  
You Li ◽  
Babu Guda
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Fusion Gene ◽  
Cancer Cell Lines ◽  
Gene Identification ◽  
Primary Tumors ◽  
Common Cancer

Comprehensive Genomic Alterations in Common Cancer Cell Lines Revealed by Exome Sequencing

2013 ◽  
pp. 165-182
Author(s):  
Han Chang ◽  
Donald G. Jackson ◽  
Paul S. Kayne ◽  
Petra B. Ross-Macdonald ◽  
Rolf-Peter Ryseck ◽  
...  
Keyword(s):  
Exome Sequencing ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Genomic Alterations ◽  
Common Cancer

scholarly journals Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents

RSC Advances ◽  
2015 ◽  
Vol 5 (116) ◽  
pp. 96222-96229 ◽  
Author(s):  
Vinicius R. Campos ◽  
Anna C. Cunha ◽  
Wanderson A. Silva ◽  
Vitor F. Ferreira ◽  
Carla Santos de Sousa ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
New Class ◽  
Hct 116

A novel series of carbohydrate-based naphthoquinones was synthesized and evaluated for cytotoxicity against different human cancer cell lines (HCT-116, A-549 and MDA-MB 435). The compounds derived from juglone showed better cytotoxicity profiles.

scholarly journals Deep sequencing of 3 cancer cell lines on 2 sequencing platforms

2019 ◽  
Author(s):  
Kanika Arora ◽  
Minita Shah ◽  
Molly Johnson ◽  
Rashesh Sanghvi ◽  
Jennifer Shelton ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Deep Sequencing ◽  
Normal Cell ◽  
Cancer Genomics ◽  
Cancer Cell Lines ◽  
High Confidence ◽  
Sequencing Platform ◽  
Common Cancer ◽  
Sequencing Platforms

AbstractTo test the performance of a new sequencing platform, develop an updated somatic calling pipeline and establish a reference for future benchmarking experiments, we sequenced 3 common cancer cell lines along with their matched normal cell lines to great sequencing depths (up to 278X coverage) on both Illumina HiSeqX and NovaSeq sequencing instruments. Somatic calling was generally consistent between the two platforms despite minor differences at the read level. We designed and implemented a novel pipeline for the analysis of tumor-normal samples, using multiple variant callers. We show that coupled with a high-confidence filtering strategy, it improves the accuracy of somatic calls. We also demonstrate the utility of the dataset by creating an artificial purity ladder to evaluate the somatic pipeline and benchmark methods for estimating purity and ploidy from tumor-normal pairs. The data and results of the pipeline are made accessible to the cancer genomics community.

Synthesis and antiproliferative efficiency of novel bis(imidazol-1-yl)vinyl-1,2,4-oxadiazoles

2016 ◽  
Vol 40 (3) ◽  
pp. 2823-2828 ◽  
Author(s):  
Kebballi N. Nandeesh ◽  
Hassan A. Swarup ◽  
Nagarakere C. Sandhya ◽  
Chakrabhavi D. Mohan ◽  
Chottanahalli S. Pavan Kumar ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
New Class

A new class of bis(imidazol)vinyl-1,2,4-oxadiazoles were synthesised and their anti-proliferative efficiency was tested against HCT116 and A549 cancer cell lines.

1-Aryl-4,6-dihydropyrazolo[4,3-d][1]benzazepin-5(1H)-ones: A new class of antiproliferative agents with selectivity for human leukemia and breast cancer cell lines

2007 ◽  
Vol 42 (11-12) ◽  
pp. 1317-1324 ◽  
Author(s):  
Simone Kohfeld ◽  
Peter G. Jones ◽  
Frank Totzke ◽  
Christoph Schächtele ◽  
Michael H.G. Kubbutat ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Human Leukemia ◽  
Antiproliferative Agents ◽  
New Class

scholarly journals Cell line cross-contamination initiative: An interactive reference database of STR profiles covering common cancer cell lines

2010 ◽  
Vol 126 (1) ◽  
pp. 303-304 ◽  
Author(s):  
Wilhelm G. Dirks ◽  
Roderick A. F. MacLeod ◽  
Yukio Nakamura ◽  
Arihiro Kohara ◽  
Yvonne Reid ◽  
...  
Keyword(s):  
Cell Line ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Reference Database ◽  
Cross Contamination ◽  
Common Cancer ◽  
Line Cross

Enantiomers of tetrahedral metal–organic cages: a new class of highly efficient G-quadruplex ligands with potential anticancer activities

2016 ◽  
Vol 52 (67) ◽  
pp. 10261-10264 ◽  
Author(s):  
Sai-Fei Xi ◽  
Ling-Yu Bao ◽  
Jian-Guo Lin ◽  
Qing-Zhu Liu ◽  
Ling Qiu ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Anticancer Activities ◽  
Quadruplex Dna ◽  
New Class ◽  
Highly Efficient ◽  
G Quadruplex ◽  
Metal Organic

A new class of chiral tetrahedral cages efficiently stabilized antiparallel G-quadruplex DNA with moderate enantioselectivity and displayed promising cytotoxicity against several cancer cell lines.

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