Design, synthesis, and biological evaluation of novel morpholinated isatin–quinoline hybrids as potent anti‐breast cancer agents

Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

RSC Advances ◽

10.1039/d0ra04970k ◽

2020 ◽

Vol 10 (43) ◽

pp. 25517-25528

Author(s):

Ahmad Junaid ◽

Felicia Phei Lin Lim ◽

Edward R. T. Tiekink ◽

Anton V. Dolzhenko

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Anticancer Agents ◽

Breast Cancer Cells ◽

Triple Negative ◽

3D Qsar ◽

Qsar Model ◽

Biological Evaluation ◽

Design Synthesis ◽

New highly potent and selective 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed and prepared using the 3D-QSAR model developed earlier.

Design, synthesis and biological evaluation of novel HDAC inhibitors with improved pharmacokinetic profile in breast cancer

10.1016/j.ejmech.2020.112648 ◽

2020 ◽

Vol 205 ◽

pp. 112648

Author(s):

Dahong Yao ◽

Chenyang Li ◽

Jin Jiang ◽

Jian Huang ◽

Jinhui Wang ◽

...

Keyword(s):

Breast Cancer ◽

Hdac Inhibitors ◽

Pharmacokinetic Profile ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of 2-(phenoxymethyl)-5-phenyl-1,3,4-oxadiazole derivatives as anti-breast cancer agents

10.1016/j.ejmech.2019.02.033 ◽

2019 ◽

Vol 168 ◽

pp. 1-10 ◽

Cited By ~ 11

Author(s):

K. Lakshmithendral ◽

K. Saravanan ◽

R. Elancheran ◽

K. Archana ◽

N. Manikandan ◽

...

Keyword(s):

Breast Cancer ◽

Biological Evaluation ◽

Design Synthesis ◽

Oxadiazole Derivatives ◽

Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells

10.1016/j.ejmech.2017.07.056 ◽

2017 ◽

Vol 139 ◽

pp. 305-324 ◽

Cited By ~ 11

Author(s):

Anver Basha Shaik ◽

Garikapati Koteswara Rao ◽

G. Bharath Kumar ◽

Nibeditha Patel ◽

Vangala Santhosh Reddy ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Biological Evaluation ◽

Mtor Pathway ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of novel tetrahydrothieno [2,3-c]pyridine substitued benzoyl thiourea derivatives as PAK1 inhibitors in triple negative breast cancer

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2020.1797710 ◽

2020 ◽

Vol 35 (1) ◽

pp. 1524-1538

Author(s):

Dahong Yao ◽

Jian Huang ◽

Jinhui Wang ◽

Zhendan He ◽

Jin Zhang

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Biological Evaluation ◽

Design Synthesis ◽

Thiourea Derivatives ◽

Design, synthesis, and biological evaluation of quinazolin-4(3H)-one derivatives co-targeting poly(ADP-ribose) polymerase-1 and bromodomain containing protein 4 for breast cancer therapy

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2020.06.003 ◽

2020 ◽

Author(s):

Xiaosa Chang ◽

Dejuan Sun ◽

Danfeng Shi ◽

Guan Wang ◽

Yanmei Chen ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Biological Evaluation ◽

Breast Cancer Therapy ◽

Design Synthesis ◽

Abstract LB-067: Design, synthesis and biological evaluation of novel selenocyanide histone deacetylase inhibitor as anti-triple negative breast cancer agents

10.1158/1538-7445.am2017-lb-067 ◽

2017 ◽

Author(s):

Chu Tang ◽

Yang Du ◽

Jie Tian

Keyword(s):

Breast Cancer ◽

Histone Deacetylase ◽

Triple Negative Breast Cancer ◽

Histone Deacetylase Inhibitor ◽

Triple Negative ◽

Biological Evaluation ◽

Design Synthesis ◽

Deacetylase Inhibitor ◽

Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breast cancer cell lines

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2020.1804383 ◽

2020 ◽

Vol 35 (1) ◽

pp. 1641-1656

Author(s):

Marwa Sharaky ◽

Marwa Kamel ◽

Marwa A. Aziz ◽

Mervat Omran ◽

Monira M. Rageh ◽

...

Keyword(s):

Breast Cancer ◽

Antitumor Activity ◽

Breast Cancer Cell ◽

Biological Evaluation ◽

Breast Cancer Cell Lines ◽

Urea Derivative ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Resistant Breast Cancer Cell ◽

Potential Antitumor

Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer

10.1016/j.ejmech.2020.112281 ◽

2020 ◽

Vol 195 ◽

pp. 112281

Author(s):

Ming He ◽

Wentao Ning ◽

Zhiye Hu ◽

Jian Huang ◽

Chune Dong ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Design Synthesis ◽

Lysine Specific Demethylase ◽