Spatial gradient effects of 120 mT static magnetic field on endothelial tubular formation in vitro

This study was undertaken to investigate the influence of a homogenous and uniform static magnetic field (SMF) on the main blood cell counts in vitro experiment. Fresh blood samples were collected from albino rats and exposed to SMF (2.4, 6, 25, 50, 75, and 100 mT) versus 15–60 min. Results showed a significant change of blood counts under the low field effects. A 2.4 mT was a trend of white blood cells (WBCs) count increase non-linearly. However, a 6 mT exposure reduced WBCs with about 39%. Other variations fluctuated within 30%. The 25 mT decreased red blood cells (RBCs), hemoglobin, and hematocrit levels with 13% similarly. The lower exposure field, (2.4 and 6) mT, and effects on RBCs were 6% fluctuation. The 6 mT reduced platelet counts with half in comparison to control blood samples. About 20% increase obtained due to 50 mT exposure during all period. None of 75 and 100 mT exposures dominated blood counts alterations. The quiet magnetic field exposure for a certain time can be interesting to control blood cell count-related diseases.

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INCREASED APOPTOSIS, CHANGES IN INTRACELLULAR Ca2+, AND FUNCTIONAL ALTERATIONS IN LYMPHOCYTES AND MACROPHAGES AFTER IN VITRO EXPOSURE TO STATIC MAGNETIC FIELD

Journal of Toxicology and Environmental Health Part A ◽

10.1080/009841098159033 ◽

1998 ◽

Vol 54 (1) ◽

pp. 63-76 ◽

Cited By ~ 69

Author(s):

Denis Flipo Michel Fournier Corinne

Keyword(s):

Magnetic Field ◽

Static Magnetic Field ◽

In Vitro Exposure

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Strong Static Magnetic Field Stimulates Bone Formation to a Definite Orientation In Vitro and In Vivo

Journal of Bone and Mineral Research ◽

10.1359/jbmr.2002.17.10.1814 ◽

2002 ◽

Vol 17 (10) ◽

pp. 1814-1821 ◽

Cited By ~ 130

Author(s):

Hiroko Kotani ◽

Hiroshi Kawaguchi ◽

Takashi Shimoaka ◽

Masakazu Iwasaka ◽

Shoogo Ueno ◽

...

Keyword(s):

Magnetic Field ◽

Bone Formation ◽

Static Magnetic Field

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Exposure to inhomogeneous static magnetic field beneficially affects allergic inflammation in a murine model

Journal of The Royal Society Interface ◽

10.1098/rsif.2014.0097 ◽

2014 ◽

Vol 11 (95) ◽

pp. 20140097 ◽

Cited By ~ 12

Author(s):

Anikó Csillag ◽

Brahma V. Kumar ◽

Krisztina Szabó ◽

Mária Szilasi ◽

Zsuzsa Papp ◽

...

Keyword(s):

Magnetic Field ◽

Static Magnetic Field ◽

Murine Model ◽

Human Study ◽

Allergic Inflammation ◽

Pollen Extract ◽

Ros Production ◽

The Impact

Previous observations suggest that static magnetic field (SMF)-exposure acts on living organisms partly through reactive oxygen species (ROS) reactions. In this study, we aimed to define the impact of SMF-exposure on ragweed pollen extract (RWPE)-induced allergic inflammation closely associated with oxidative stress. Inhomogeneous SMF was generated with an apparatus validated previously providing a peak-to-peak magnetic induction of the dominant SMF component 389 mT by 39 T m −1 lateral gradient in the in vivo and in vitro experiments, and 192 mT by 19 T m −1 in the human study at the 3 mm target distance. Effects of SMF-exposure were studied in a murine model of allergic inflammation and also in human provoked skin allergy. We found that even a single 30-min exposure of mice to SMF immediately following intranasal RWPE challenge significantly lowered the increase in the total antioxidant capacity of the airways and decreased allergic inflammation. Repeated (on 3 consecutive days) or prolonged (60 min) exposure to SMF after RWPE challenge decreased the severity of allergic responses more efficiently than a single 30-min treatment. SMF-exposure did not alter ROS production by RWPE under cell-free conditions, while diminished RWPE-induced increase in the ROS levels in A549 epithelial cells. Results of the human skin prick tests indicated that SMF-exposure had no significant direct effect on provoked mast cell degranulation. The observed beneficial effects of SMF are likely owing to the mobilization of cellular ROS-eliminating mechanisms rather than direct modulation of ROS production by pollen NAD(P)H oxidases.

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