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Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation
Biotechnology Journal
◽
10.1002/biot.202100142
◽
2021
◽
pp. 2100142
Author(s):
Ren Liu
◽
Yixiao Zhang
◽
Amit Kumar
◽
Steven Huhn
◽
Laurie Hullinger
◽
...
Keyword(s):
Cell Culture
◽
Host Selection
◽
Sodium Chlorate
◽
Recombinant Antibodies
◽
Cho Cell
◽
Tyrosine Sulfation
◽
Cho Cell Culture
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Continuous precipitation of recombinant antibodies from CHO cell culture supernatant by calcium-phosphate flocculation and cold ethanol precipitation
New Biotechnology
◽
10.1016/j.nbt.2014.05.1753
◽
2014
◽
Vol 31
◽
pp. S61-S62
Author(s):
Nikolaus Hammerschmidt
◽
Anne Tscheließnig
◽
Bernhard Helk
◽
Alois Jungbauer
Keyword(s):
Cell Culture
◽
Calcium Phosphate
◽
Culture Supernatant
◽
Recombinant Antibodies
◽
Cell Culture Supernatant
◽
Cho Cell
◽
Continuous Precipitation
◽
Ethanol Precipitation
◽
Cho Cell Culture
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Benchmarking of commercially available CHO cell culture media for antibody production
Applied Microbiology and Biotechnology
◽
10.1007/s00253-015-6514-4
◽
2015
◽
Vol 99
(11)
◽
pp. 4645-4657
◽
Cited By ~ 59
Author(s):
David Reinhart
◽
Lukas Damjanovic
◽
Christian Kaisermayer
◽
Renate Kunert
Keyword(s):
Cell Culture
◽
Antibody Production
◽
Culture Media
◽
Cho Cell
◽
Cell Culture Media
◽
Cho Cell Culture
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Equal mixing time enables scale‐down and optimisation of a CHO cell culture process using a shaken microbioreactor system
Biotechnology Journal
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10.1002/biot.202100360
◽
2021
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Author(s):
Vincent Wiegmann
◽
Richard A. Gardner
◽
Daniel I. R. Spencer
◽
Frank Baganz
Keyword(s):
Cell Culture
◽
Mixing Time
◽
Cell Culture Process
◽
Cho Cell
◽
Scale Down
◽
Culture Process
◽
Cho Cell Culture
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Protein A affinity chromatography of Chinese hamster ovary (CHO) cell culture broths containing biopharmaceutical monoclonal antibody (mAb): Experiments and mechanistic transport, binding and equilibrium modeling
Journal of Chromatography B
◽
10.1016/j.jchromb.2018.02.032
◽
2018
◽
Vol 1083
◽
pp. 44-56
◽
Cited By ~ 9
Author(s):
Matic Grom
◽
Mirijam Kozorog
◽
Simon Caserman
◽
Andrej Pohar
◽
Blaž Likozar
Keyword(s):
Cell Culture
◽
Monoclonal Antibody
◽
Affinity Chromatography
◽
Chinese Hamster Ovary
◽
Protein A
◽
Chinese Hamster
◽
Cho Cell
◽
Equilibrium Modeling
◽
Cho Cell Culture
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Reduction of charge variants by CHO cell culture process optimization
Cytotechnology
◽
10.1007/s10616-020-00375-x
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2020
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Vol 72
(2)
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pp. 259-269
◽
Cited By ~ 1
Author(s):
Zhibing Weng
◽
Jian Jin
◽
ChunHua Shao
◽
Huazhong Li
Keyword(s):
Cell Culture
◽
Process Optimization
◽
Cell Culture Process
◽
Cho Cell
◽
Culture Process
◽
Cho Cell Culture
◽
Charge Variants
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CONTINUOUS SUSPENSION CHO CELL CULTURE
Animal Cell Technology
◽
10.1016/b978-0-7506-1845-8.50052-1
◽
1994
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pp. 215-217
Author(s):
Henrik Albahn Hansen
◽
Claus Emborg
Keyword(s):
Cell Culture
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Cho Cell
◽
Cho Cell Culture
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An investigation of nucleotide sugar dynamics under the galactose supplementation in CHO cell culture
Process Biochemistry
◽
10.1016/j.procbio.2019.03.020
◽
2019
◽
Vol 81
◽
pp. 165-174
◽
Cited By ~ 6
Author(s):
Sha Sha
◽
Seongkyu Yoon
Keyword(s):
Cell Culture
◽
Cho Cell
◽
Nucleotide Sugar
◽
Cho Cell Culture
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Model‐based optimization of antibody galactosylation in CHO cell culture
Biotechnology and Bioengineering
◽
10.1002/bit.26960
◽
2019
◽
Vol 116
(7)
◽
pp. 1612-1626
◽
Cited By ~ 13
Author(s):
Pavlos Kotidis
◽
Philip Jedrzejewski
◽
Si Nga Sou
◽
Christopher Sellick
◽
Karen Polizzi
◽
...
Keyword(s):
Cell Culture
◽
Cho Cell
◽
Model Based
◽
Cho Cell Culture
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Novel column generation-based optimization approach for poly-pathway kinetic model applied to CHO cell culture
Metabolic Engineering Communications
◽
10.1016/j.mec.2018.e00083
◽
2019
◽
Vol 8
◽
pp. e00083
◽
Cited By ~ 3
Author(s):
Erika Hagrot
◽
Hildur Æsa Oddsdóttir
◽
Meeri Mäkinen
◽
Anders Forsgren
◽
Véronique Chotteau
Keyword(s):
Cell Culture
◽
Kinetic Model
◽
Column Generation
◽
Optimization Approach
◽
Cho Cell
◽
Cho Cell Culture
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Dynamics of immature mAb glycoform secretion during CHO cell culture: An integrated modelling framework
Biotechnology Journal
◽
10.1002/biot.201400663
◽
2016
◽
Vol 11
(5)
◽
pp. 610-623
◽
Cited By ~ 23
Author(s):
Ioscani Jimenez del Val
◽
Yuzhou Fan
◽
Dietmar Weilguny
Keyword(s):
Cell Culture
◽
Integrated Modelling
◽
Cho Cell
◽
Modelling Framework
◽
Cho Cell Culture
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