Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose

2002 ◽  
Vol 77 (5) ◽  
pp. 553-563 ◽  
Author(s):  
Tina M. Larson ◽  
Martin Gawlitzek ◽  
Heather Evans ◽  
Urs Albers ◽  
Jerry Cacia

1982 ◽  
Vol 5 (9) ◽  
pp. 1749-1762
Author(s):  
Y. Hazeyama ◽  
W. J. Valko ◽  
H. T. Ravert ◽  
N. D. Heindel ◽  
R. L. Moretti


1978 ◽  
Vol 156 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Ajit S. Bhown ◽  
John E. Mole ◽  
William L. Hollaway ◽  
J.Claude Bennett


1979 ◽  
Vol 12 (6) ◽  
pp. 345-348 ◽  
Author(s):  
E. W. Bachmann ◽  
J. Frei ◽  
M. Muehlemann


2019 ◽  
Author(s):  
Stephanie Andraos ◽  
Michael Goy ◽  
Ben Albert ◽  
Martin Kussmann ◽  
Eric B. Thorstensen ◽  
...  

AbstractAmino acids (AAs) and one-carbon (1-C) compounds are involved in a range of key metabolic pathways, and mediate numerous health and disease processes in the human body. Previous assays have quantified a limited selection of these compounds. Here, we describe an analytical method for the simultaneous quantification of 37 1-C metabolites, amino acids, precursors, and plasmalogens using reversed-phase ultra-high pressure liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). Compound extraction from human plasma was tested manually before being robotically automated. The final analytical panel was validated on human plasma samples. Our automated and multiplexed method holds promise for application to large cohort studies.



1997 ◽  
pp. 429-434
Author(s):  
Eva Balslev Jorgensen ◽  
Antoni Casablancas ◽  
òGloria González ◽  
Francesc Gòdia


2010 ◽  
pp. 853-859 ◽  
Author(s):  
Sven Ansorge ◽  
Olivier Henry ◽  
Marc Aucoin ◽  
Robert Voyer ◽  
John P. Carvell ◽  
...  


2018 ◽  
Vol 13 (4) ◽  
pp. 1700607 ◽  
Author(s):  
Stephen Goldrick ◽  
Kenneth Lee ◽  
Christopher Spencer ◽  
William Holmes ◽  
Marcel Kuiper ◽  
...  


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