Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture

2013 ◽  
Vol 110 (7) ◽  
pp. 2013-2024 ◽  
Author(s):  
Neil Templeton ◽  
Jason Dean ◽  
Pranhitha Reddy ◽  
Jamey D. Young
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Oxidative Metabolism ◽  
Fed Batch ◽  
Cho Cell ◽  
Cho Cell Culture

scholarly journals Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

2014 ◽  
Vol 112 (3) ◽  
pp. 521-535 ◽  
Author(s):  
Yuzhou Fan ◽  
Ioscani Jimenez Del Val ◽  
Christian Müller ◽  
Jette Wagtberg Sen ◽  
Søren Kofoed Rasmussen ◽  
...  
Keyword(s):  
Cell Culture ◽  
Amino Acid ◽  
Glucose Metabolism ◽  
Antibody Production ◽  
Fed Batch ◽  
Cho Cell ◽  
Cho Cell Culture

scholarly journals Benchmarking of commercially available CHO cell culture media for antibody production

2015 ◽  
Vol 99 (11) ◽  
pp. 4645-4657 ◽  
Author(s):  
David Reinhart ◽  
Lukas Damjanovic ◽  
Christian Kaisermayer ◽  
Renate Kunert
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

scholarly journals Benchmarking of commercially available CHO cell culture media for antibody production

2013 ◽  
Vol 7 (S6) ◽  
Author(s):  
David Reinhart ◽  
Christian Kaisermayer ◽  
Lukas Damjanovic ◽  
Renate Kunert
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect

2018 ◽  
Vol 115 (9) ◽  
pp. 2315-2327 ◽  
Author(s):  
Maria Buchsteiner ◽  
Lake‐Ee Quek ◽  
Peter Gray ◽  
Lars K. Nielsen
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Warburg Effect ◽  
Cho Cell ◽  
Culture Performance ◽  
Cho Cell Culture ◽  
The Warburg Effect

scholarly journals BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture

2019 ◽  
Vol 14 (10) ◽  
pp. 1900130 ◽  
Author(s):  
Tae Kwang Ha ◽  
Anders H. Hansen ◽  
Helene F. Kildegaard ◽  
Gyun Min Lee
Keyword(s):  
Cell Culture ◽  
Er Stress ◽  
Antibody Production ◽  
Recombinant Antibody ◽  
Cho Cell ◽  
Recombinant Antibody Production ◽  
Cho Cell Culture

Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture

2012 ◽  
Vol 109 (6) ◽  
pp. 1415-1429 ◽  
Author(s):  
Suresh Selvarasu ◽  
Ying Swan Ho ◽  
William P. K. Chong ◽  
Niki S. C. Wong ◽  
Faraaz N. K. Yusufi ◽  
...  
Keyword(s):  
Cell Culture ◽  
In Silico ◽  
Fed Batch ◽  
Cho Cell ◽  
In Silico Modeling ◽  
Cho Cell Culture ◽  
Metabolomics Analysis
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