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Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation
Biotechnology and Bioengineering
◽
10.1002/bit.25450
◽
2014
◽
Vol 112
(3)
◽
pp. 521-535
◽
Cited By ~ 89
Author(s):
Yuzhou Fan
◽
Ioscani Jimenez Del Val
◽
Christian Müller
◽
Jette Wagtberg Sen
◽
Søren Kofoed Rasmussen
◽
...
Keyword(s):
Cell Culture
◽
Amino Acid
◽
Glucose Metabolism
◽
Antibody Production
◽
Fed Batch
◽
Cho Cell
◽
Cho Cell Culture
Download Full-text
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References
Fed-Batch CHO Cell Culture for Lab-Scale Antibody Production
Methods in Molecular Biology - Recombinant Glycoprotein Production
◽
10.1007/978-1-4939-7312-5_12
◽
2017
◽
pp. 147-161
◽
Cited By ~ 1
Author(s):
Yuzhou Fan
◽
Daniel Ley
◽
Mikael Rørdam Andersen
Keyword(s):
Cell Culture
◽
Antibody Production
◽
Fed Batch
◽
Cho Cell
◽
Cho Cell Culture
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Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture
Biotechnology and Bioengineering
◽
10.1002/bit.24858
◽
2013
◽
Vol 110
(7)
◽
pp. 2013-2024
◽
Cited By ~ 113
Author(s):
Neil Templeton
◽
Jason Dean
◽
Pranhitha Reddy
◽
Jamey D. Young
Keyword(s):
Cell Culture
◽
Antibody Production
◽
Oxidative Metabolism
◽
Fed Batch
◽
Cho Cell
◽
Cho Cell Culture
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Benchmarking of commercially available CHO cell culture media for antibody production
Applied Microbiology and Biotechnology
◽
10.1007/s00253-015-6514-4
◽
2015
◽
Vol 99
(11)
◽
pp. 4645-4657
◽
Cited By ~ 59
Author(s):
David Reinhart
◽
Lukas Damjanovic
◽
Christian Kaisermayer
◽
Renate Kunert
Keyword(s):
Cell Culture
◽
Antibody Production
◽
Culture Media
◽
Cho Cell
◽
Cell Culture Media
◽
Cho Cell Culture
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Multi-stage population balance model to understand the dynamics of fed-batch CHO cell culture
Computer Aided Chemical Engineering - 27th European Symposium on Computer Aided Process Engineering
◽
10.1016/b978-0-444-63965-3.50472-4
◽
2017
◽
pp. 2821-2826
Author(s):
Sakhr Alhuthali
◽
Sarah Fadda
◽
Cher H. Goey
◽
Cleo Kontoravdi
Keyword(s):
Cell Culture
◽
Population Balance
◽
Balance Model
◽
Population Balance Model
◽
Fed Batch
◽
Cho Cell
◽
Multi Stage
◽
Cho Cell Culture
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Benchmarking of commercially available CHO cell culture media for antibody production
BMC Proceedings
◽
10.1186/1753-6561-7-s6-p13
◽
2013
◽
Vol 7
(S6)
◽
Cited By ~ 1
Author(s):
David Reinhart
◽
Christian Kaisermayer
◽
Lukas Damjanovic
◽
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Keyword(s):
Cell Culture
◽
Antibody Production
◽
Culture Media
◽
Cho Cell
◽
Cell Culture Media
◽
Cho Cell Culture
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Poly-pathway model, a novel approach to simulate multiple metabolic states by reaction network-based model – Application to amino acid depletion in CHO cell culture
Journal of Biotechnology
◽
10.1016/j.jbiotec.2017.05.026
◽
2017
◽
Vol 259
◽
pp. 235-247
◽
Cited By ~ 6
Author(s):
Erika Hagrot
◽
Hildur Æsa Oddsdóttir
◽
Joan Gonzalez Hosta
◽
Elling W. Jacobsen
◽
Véronique Chotteau
Keyword(s):
Cell Culture
◽
Amino Acid
◽
Reaction Network
◽
Cho Cell
◽
Pathway Model
◽
Model Application
◽
Novel Approach
◽
Metabolic States
◽
Cho Cell Culture
◽
Amino Acid Depletion
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Optimizing amino acid composition of CHO cell culture media for a fusion protein production
Process Biochemistry
◽
10.1016/j.procbio.2011.03.014
◽
2011
◽
Vol 46
(7)
◽
pp. 1423-1429
◽
Cited By ~ 54
Author(s):
Zizhuo Xing
◽
Brian Kenty
◽
Inna Koyrakh
◽
Michael Borys
◽
Shih-Hsie Pan
◽
...
Keyword(s):
Cell Culture
◽
Amino Acid
◽
Fusion Protein
◽
Amino Acid Composition
◽
Acid Composition
◽
Protein Production
◽
Culture Media
◽
Cho Cell
◽
Cell Culture Media
◽
Cho Cell Culture
Download Full-text
RETRACTED: Poly-pathway model, a novel approach to simulate multiple metabolic states by reaction network-based model – Application to amino acid depletion in CHO cell culture
Journal of Biotechnology
◽
10.1016/j.jbiotec.2016.03.015
◽
2016
◽
Vol 228
◽
pp. 37-49
◽
Cited By ~ 6
Author(s):
Erika Hagrot
◽
Hildur Æsa Oddsdóttir
◽
Joan Gonzalez Hosta
◽
Elling W. Jacobsen
◽
Véronique Chotteau
Keyword(s):
Cell Culture
◽
Amino Acid
◽
Reaction Network
◽
Cho Cell
◽
Pathway Model
◽
Model Application
◽
Novel Approach
◽
Metabolic States
◽
Cho Cell Culture
◽
Amino Acid Depletion
Download Full-text
Using MVDA with Stoichiometric Balances to Optimize Amino Acid Concentrations in Chemically Defined CHO Cell Culture Medium for Improved Culture Performance
Biotechnology and Bioengineering
◽
10.1002/bit.27998
◽
2021
◽
Author(s):
Taha Salim
◽
Gaurav Chauhan
◽
Neil Templeton
◽
Wai Lam W. Ling
Keyword(s):
Cell Culture
◽
Amino Acid
◽
Culture Medium
◽
Cell Culture Medium
◽
Cho Cell
◽
Culture Performance
◽
Cho Cell Culture
◽
Amino Acid Concentrations
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Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect
Biotechnology and Bioengineering
◽
10.1002/bit.26724
◽
2018
◽
Vol 115
(9)
◽
pp. 2315-2327
◽
Cited By ~ 14
Author(s):
Maria Buchsteiner
◽
Lake‐Ee Quek
◽
Peter Gray
◽
Lars K. Nielsen
Keyword(s):
Cell Culture
◽
Antibody Production
◽
Warburg Effect
◽
Cho Cell
◽
Culture Performance
◽
Cho Cell Culture
◽
The Warburg Effect
Download Full-text
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