scholarly journals Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

2014 ◽  
Vol 112 (3) ◽  
pp. 521-535 ◽  
Author(s):  
Yuzhou Fan ◽  
Ioscani Jimenez Del Val ◽  
Christian Müller ◽  
Jette Wagtberg Sen ◽  
Søren Kofoed Rasmussen ◽  
...  
Keyword(s):  
Cell Culture ◽  
Amino Acid ◽  
Glucose Metabolism ◽  
Antibody Production ◽  
Fed Batch ◽  
Cho Cell ◽  
Cho Cell Culture

Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture

2013 ◽  
Vol 110 (7) ◽  
pp. 2013-2024 ◽  
Author(s):  
Neil Templeton ◽  
Jason Dean ◽  
Pranhitha Reddy ◽  
Jamey D. Young
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Oxidative Metabolism ◽  
Fed Batch ◽  
Cho Cell ◽  
Cho Cell Culture

scholarly journals Benchmarking of commercially available CHO cell culture media for antibody production

2015 ◽  
Vol 99 (11) ◽  
pp. 4645-4657 ◽  
Author(s):  
David Reinhart ◽  
Lukas Damjanovic ◽  
Christian Kaisermayer ◽  
Renate Kunert
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

scholarly journals Benchmarking of commercially available CHO cell culture media for antibody production

2013 ◽  
Vol 7 (S6) ◽  
Author(s):  
David Reinhart ◽  
Christian Kaisermayer ◽  
Lukas Damjanovic ◽  
Renate Kunert
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

scholarly journals Poly-pathway model, a novel approach to simulate multiple metabolic states by reaction network-based model – Application to amino acid depletion in CHO cell culture

2017 ◽  
Vol 259 ◽  
pp. 235-247 ◽  
Author(s):  
Erika Hagrot ◽  
Hildur Æsa Oddsdóttir ◽  
Joan Gonzalez Hosta ◽  
Elling W. Jacobsen ◽  
Véronique Chotteau
Keyword(s):  
Cell Culture ◽  
Amino Acid ◽  
Reaction Network ◽  
Cho Cell ◽  
Pathway Model ◽  
Model Application ◽  
Novel Approach ◽  
Metabolic States ◽  
Cho Cell Culture ◽  
Amino Acid Depletion

Optimizing amino acid composition of CHO cell culture media for a fusion protein production

2011 ◽  
Vol 46 (7) ◽  
pp. 1423-1429 ◽  
Author(s):  
Zizhuo Xing ◽  
Brian Kenty ◽  
Inna Koyrakh ◽  
Michael Borys ◽  
Shih-Hsie Pan ◽  
...  
Keyword(s):  
Cell Culture ◽  
Amino Acid ◽  
Fusion Protein ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Protein Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect

2018 ◽  
Vol 115 (9) ◽  
pp. 2315-2327 ◽  
Author(s):  
Maria Buchsteiner ◽  
Lake‐Ee Quek ◽  
Peter Gray ◽  
Lars K. Nielsen
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Warburg Effect ◽  
Cho Cell ◽  
Culture Performance ◽  
Cho Cell Culture ◽  
The Warburg Effect
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