Multi-stage population balance model to understand the dynamics of fed-batch CHO cell culture

2017 ◽  
pp. 2821-2826
Author(s):  
Sakhr Alhuthali ◽  
Sarah Fadda ◽  
Cher H. Goey ◽  
Cleo Kontoravdi
Keyword(s):  
Cell Culture ◽  
Population Balance ◽  
Balance Model ◽  
Population Balance Model ◽  
Fed Batch ◽  
Cho Cell ◽  
Multi Stage ◽  
Cho Cell Culture

scholarly journals A multi-stage multi-component transfer rate morphological population balance model for crystallization processes

CrystEngComm ◽  
2019 ◽  
Vol 21 (28) ◽  
pp. 4212-4220 ◽  
Author(s):  
Yi D. Shu ◽  
Jing J. Liu ◽  
Yang Zhang ◽  
Xue Z. Wang
Keyword(s):  
Crystal Growth ◽  
Single Crystals ◽  
Transfer Rate ◽  
Population Balance ◽  
Balance Model ◽  
Population Balance Model ◽  
Multi Stage ◽  
Non Equilibrium

A model was proposed for modeling the non-equilibrium crystal growth of single crystals (Y. D. Shu, Y. Li, Y. Zhang, J. J. Liu and X. Z. Wang, CrystEngComm, 2018, 20, 5143–5153).

scholarly journals Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

2014 ◽  
Vol 112 (3) ◽  
pp. 521-535 ◽  
Author(s):  
Yuzhou Fan ◽  
Ioscani Jimenez Del Val ◽  
Christian Müller ◽  
Jette Wagtberg Sen ◽  
Søren Kofoed Rasmussen ◽  
...  
Keyword(s):  
Cell Culture ◽  
Amino Acid ◽  
Glucose Metabolism ◽  
Antibody Production ◽  
Fed Batch ◽  
Cho Cell ◽  
Cho Cell Culture

Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture

2012 ◽  
Vol 109 (6) ◽  
pp. 1415-1429 ◽  
Author(s):  
Suresh Selvarasu ◽  
Ying Swan Ho ◽  
William P. K. Chong ◽  
Niki S. C. Wong ◽  
Faraaz N. K. Yusufi ◽  
...  
Keyword(s):  
Cell Culture ◽  
In Silico ◽  
Fed Batch ◽  
Cho Cell ◽  
In Silico Modeling ◽  
Cho Cell Culture ◽  
Metabolomics Analysis

scholarly journals A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture

2015 ◽  
Vol 112 (10) ◽  
pp. 2172-2184 ◽  
Author(s):  
Yuzhou Fan ◽  
Ioscani Jimenez Del Val ◽  
Christian Müller ◽  
Anne Mathilde Lund ◽  
Jette Wagtberg Sen ◽  
...  
Keyword(s):  
Cell Culture ◽  
Glucose Starvation ◽  
Fed Batch ◽  
Cho Cell ◽  
Culture Duration ◽  
Cho Cell Culture ◽  
Effect Of Glucose

Conversion of a CHO cell culture process from perfusion to fed-batch technology without altering product quality

2006 ◽  
Vol 123 (1) ◽  
pp. 106-116 ◽  
Author(s):  
F. Meuwly ◽  
U. Weber ◽  
T. Ziegler ◽  
A. Gervais ◽  
R. Mastrangeli ◽  
...  
Keyword(s):  
Cell Culture ◽  
Product Quality ◽  
Cell Culture Process ◽  
Fed Batch ◽  
Cho Cell ◽  
Culture Process ◽  
Cho Cell Culture
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