Heparan sulfate proteoglycan, integrin, and syndecan‐4 are mechanosensors mediating cyclic strain‐modulated endothelial gene expression in mouse embryonic stem cell‐derived endothelial cells

2019 ◽  
Vol 116 (10) ◽  
pp. 2730-2741 ◽  
Author(s):  
Maria Nikmanesh ◽  
Limary M. Cancel ◽  
Zhong‐Dong Shi ◽  
John M. Tarbell
2006 ◽  
Vol 2 (11) ◽  
pp. e158 ◽  
Author(s):  
Clive H. Glover ◽  
Michael Marin ◽  
Connie J. Eaves ◽  
Cheryl D. Helgason ◽  
James M. Piret ◽  
...  

2007 ◽  
Vol 7 ◽  
pp. 1950-1964 ◽  
Author(s):  
Anna Jezierski ◽  
Albert Swedani ◽  
Lisheng Wang

The current progress using the human embryonic stem cell (hESC) model system has provided much insight into the early origins of the hematopoietic and endothelial lineages, particularly the elusive hemangioblast. Recently, the cellular hierarchy and molecular regulation controlling hematopoietic commitment have been further elucidated. These findings not only provide new insights into early human development, but also advance the knowledge required to develop techniques capable of generating a given cell type for potential clinical applications. This review will focus on the latest advances using the hESC model system, capitalizing on the well-established mouse embryonic stem cell model system, as a means to investigate the lineage commitment events underlying the early embryonic development of human hematopoietic and endothelial cells.


2006 ◽  
Vol 75 (4) ◽  
pp. 555-561 ◽  
Author(s):  
Tadashi Furusawa ◽  
Mitsumi Ikeda ◽  
Fukashi Inoue ◽  
Katsuhiro Ohkoshi ◽  
Takehito Hamano ◽  
...  

2015 ◽  
Vol 291 (7) ◽  
pp. 3333-3345 ◽  
Author(s):  
Riki Ishibashi ◽  
Satoshi Kozuki ◽  
Sachiko Kamakura ◽  
Hideki Sumimoto ◽  
Fumiko Toyoshima

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