scholarly journals Role of Notch1 in the arterial specification and angiogenic potential of mouse embryonic stem cell-derived endothelial cells

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Jae Kyung Park ◽  
Tae Wook Lee ◽  
Eun Kyoung Do ◽  
Hye Ji Moon ◽  
Jae Ho Kim
Keyword(s):  
Endothelial Cells ◽  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cell ◽  
Angiogenic Potential

scholarly journals Development of Hematopoietic and Endothelial Cells from Human Embryonic Stem Cells: Lessons from the Studies using Mouse as a Model

2007 ◽  
Vol 7 ◽  
pp. 1950-1964 ◽  
Author(s):  
Anna Jezierski ◽  
Albert Swedani ◽  
Lisheng Wang
Keyword(s):  
Endothelial Cells ◽  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Model ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cell ◽  
Model System ◽  
Stem Cell Model ◽  
Cell Model System ◽  
Cellular Hierarchy

The current progress using the human embryonic stem cell (hESC) model system has provided much insight into the early origins of the hematopoietic and endothelial lineages, particularly the elusive hemangioblast. Recently, the cellular hierarchy and molecular regulation controlling hematopoietic commitment have been further elucidated. These findings not only provide new insights into early human development, but also advance the knowledge required to develop techniques capable of generating a given cell type for potential clinical applications. This review will focus on the latest advances using the hESC model system, capitalizing on the well-established mouse embryonic stem cell model system, as a means to investigate the lineage commitment events underlying the early embryonic development of human hematopoietic and endothelial cells.

scholarly journals The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal

Materials ◽  
2017 ◽  
Vol 10 (9) ◽  
pp. 1081 ◽  
Author(s):  
Melanie Macgregor ◽  
Rachel Williams ◽  
Joni Downes ◽  
Akash Bachhuka ◽  
Krasimir Vasilev
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Surface Topography ◽  
Cell Attachment ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cell ◽  
Self Renewal
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