Simultaneous determination of peimine and peiminine in rat plasma by LC-ESI-MS employing solid-phase extraction

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Xiaodan Wu ◽  
Juanjuan Chen ◽  
Yuanjiang Pan
Keyword(s):  
Solid Phase Extraction ◽  
Simultaneous Determination ◽  
Solid Phase ◽  
Rat Plasma ◽  
Phase Extraction ◽  
Esi Ms

Solid phase extraction procedure coupled with the chiral LC-ESI-MS/MS method for the enantioseparation and determination of butoconazole enantiomers in rat plasma and tissues: application to the enantioselective study on pharmacokinetics and tissue distribution

2021 ◽  
Author(s):  
Siman Ma ◽  
Lina Wang ◽  
Guoxian Guo ◽  
Jia Yu ◽  
Xingjie Guo
Keyword(s):  
Solid Phase Extraction ◽  
Tissue Distribution ◽  
Solid Phase ◽  
Extraction Procedure ◽  
Rat Plasma ◽  
Phase Extraction ◽  
Esi Ms ◽  
Solid Phase Extraction Procedure ◽  
Chiral Lc

A significant enantioselective difference between (−)- and (+)-butoconazole existed in the stage of not only pharmacokinetics but also tissue distribution.

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