scholarly journals Early and very early‐onset schizophrenia compared with adult‐onset schizophrenia: French FACE‐SZ database

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Nathalie Coulon ◽  
Ophélia Godin ◽  
Ewa Bulzacka ◽  
Caroline Dubertret ◽  
Jasmina Mallet ◽  
...  
Keyword(s):  
Early Onset ◽  
Adult Onset ◽  
Early Onset Schizophrenia

Auditorisches Training auch bei früher Schizophrenie-Erkrankung wirksam

2020 ◽  
Vol 88 (08) ◽  
pp. 488-489
Keyword(s):  
Early Onset ◽  
Adult Onset ◽  
Early Onset Schizophrenia

Die wenigen Studien zum kognitiven Training bei Patienten mit früh beginnender Schizophrenie (Early-Onset-Schizophrenia, EOS) zeigten einen geringeren Behandlungserfolg als das kognitive Training bei Patienten, die als Erwachsene erkrankt sind (Adult-Onset-Schizophrenia, AOS). Eine Sekundäranalyse zweier Studien prüfte jetzt, ob ein auditorisches Training (AT) bei beiden Patientengruppen unterschiedlich wirksam ist.

scholarly journals Risk Model Assessment in Early-Onset and Adult-Onset Schizophrenia Using Neurological Soft Signs

2019 ◽  
Vol 8 (9) ◽  
pp. 1443
Author(s):  
Chen ◽  
Tsai ◽  
Lin ◽  
Lu ◽  
Tan ◽  
...  
Keyword(s):  
Early Onset ◽  
Risk Model ◽  
Age At Onset ◽  
Control Group ◽  
Model Assessment ◽  
Healthy Controls ◽  
Onset Age ◽  
Adult Onset ◽  
Early Onset Schizophrenia ◽  
Neurological Soft Signs

Age at onset is one of the most important clinical features of schizophrenia that could indicate greater genetic loadings. Neurological soft signs (NSS) are considered as a potential endophenotype for schizophrenia. However, the association between NSS and different age-onset schizophrenia still remains unclear. We aimed to compare risk model in patients with early-onset schizophrenia (EOS) and adult-onset schizophrenia (AOS) with NSS. This study included 262 schizophrenia patients, 177 unaffected first-degree relatives and 243 healthy controls. We estimated the discriminant abilities of NSS models for early-onset schizophrenia (onset age < 20) and adult-onset schizophrenia (onset age ≥ 20) using three data mining methods: artificial neural networks (ANN), decision trees (DT) and logistic regression (LR). We then assessed the magnitude of NSS performance in EOS and AOS families. For the four NSS subscales, the NSS performance were greater in EOS and AOS families compared with healthy individuals. More interestingly, there were significant differences found between patients’ families and control group in the four subscales of NSS. These findings support the potential for neurodevelopmental markers to be used as schizophrenia vulnerability indicators. The NSS models had higher discriminant abilities for EOS than for AOS. NSS were more accurate in distinguishing EOS patients from healthy controls compared to AOS patients. Our results support the neurodevelopmental hypothesis that EOS has poorer performance of NSS than AOS. Hence, poorer NSS performance may be imply trait-related NSS feature in EOS.

scholarly journals Early-Onset Schizophrenia Showed Similar but More Severe Olfactory Identification Impairment Than Adult-Onset Schizophrenia

2020 ◽  
Vol 11 ◽  
Author(s):  
Ze-tian Li ◽  
Shu-bin Li ◽  
Jin-feng Wen ◽  
Xiao-yuan Zhang ◽  
Thomas Hummel ◽  
...  
Keyword(s):  
Early Onset ◽  
Adult Onset ◽  
Early Onset Schizophrenia ◽  
Olfactory Identification

Superior Temporal Gyrus Abnormalities in Early-Onset Schizophrenia: Similarities and Differences With Adult-Onset Schizophrenia

2001 ◽  
Vol 158 (8) ◽  
pp. 1299-1304 ◽  
Author(s):  
Hideo Matsumoto ◽  
Andrew Simmons ◽  
Steven Williams ◽  
Michael Hadjulis ◽  
Roderic Pipe ◽  
...  
Keyword(s):  
Early Onset ◽  
Superior Temporal Gyrus ◽  
Adult Onset ◽  
Early Onset Schizophrenia ◽  
Similarities And Differences

Neuropsychological Deficits in the Prodromal Phase and Course of an Early-Onset Schizophrenia

2014 ◽  
Vol 42 (3) ◽  
pp. 167-176 ◽  
Author(s):  
Vanessa Puetz ◽  
Thomas Günther ◽  
Berrak Kahraman-Lanzerath ◽  
Beate Herpertz-Dahlmann ◽  
Kerstin Konrad
Keyword(s):  
Verbal Memory ◽  
Early Onset ◽  
Neuropsychological Functioning ◽  
Neuropsychological Testing ◽  
Clinical Situation ◽  
Adolescent Male ◽  
Antipsychotic Treatment ◽  
Early Onset Schizophrenia ◽  
Prodromal Phase ◽  
Illness Onset

Objectives: Although clear advances have been achieved in the study of early-onset schizophrenia (EOS), little is known to date about premorbid and prodromal neuropsychological functioning in EOS. Method: Here, we report on a case of an adolescent male with EOS who underwent neuropsychological testing before and after illness onset. Results: Marked cognitive deficits in the domains of attention, set-shifting, and verbal memory were present both pre-onset and during the course of schizophrenia, though only deficits in verbal memory persisted after illness-onset and antipsychotic treatment. Conclusion: The findings of this case study suggest that impairments in the verbal memory domain are particularly prominent symptoms of cognitive impairment in prodromal EOS and persist in the course of the disorder, which further demonstrates the difficult clinical situation of adequate schooling opportunities for adolescent patients with EOS.

The Developmental Taxonomy

2018 ◽  
pp. 148-158
Author(s):  
Tara Renae McGee ◽  
Terrie E. Moffitt
Keyword(s):  
Gender Differences ◽  
Life Course ◽  
Antisocial Behavior ◽  
Early Onset ◽  
Adult Onset ◽  
Low Level ◽  
Developmental Taxonomy ◽  
Offending Behavior ◽  
Life Course Persistent ◽  
The Life Course

This chapter considers whether the peak in the age–crime curve is a function of active offenders committing more crime during adolescence or a function of more individuals actively offending in the peak years. It discusses the two main and most empirically tested typological groupings: the life-course persistent group and the adolescence limited group. The chapter then reviews the evidence on a theoretically interesting grouping: those who abstain from antisocial and offending behavior. It focuses on the debate regarding whether those who were originally thought to recover from early-onset antisocial behavior have childhood-limited antisocial behavior or exhibit low-level chronic antisocial behavior across the life course. Finally, the chapter discusses how the theory it introduces accounts for adult-onset offending and considers whether there are gender differences that need to be accounted for by the theory.

Case Series With Late-Onset Psychosis Hospitalized in a Geriatric Psychiatry Unit in Turkey: Experience in 9 Years

2003 ◽  
Vol 15 (1) ◽  
pp. 69-72 ◽  
Author(s):  
Yesne Alici-Evcimen ◽  
Turan Ertan ◽  
Engin Eker
Keyword(s):  
Early Onset ◽  
Late Onset ◽  
Case Series ◽  
Geriatric Psychiatry ◽  
Delusional Disorder ◽  
Early Onset Schizophrenia ◽  
Treatment Results ◽  
Thought Insertion ◽  
Psychiatry Department ◽  
Paranoid Psychosis

In this article we report the first series of Turkish inpatients with late-onset psychosis, and describe our 9-year experience at the only inpatient geriatric psychiatry department in Turkey. Among 420 patients hospitalized between 1993 and 2002, 27 were psychotic. In this group, eight patients were diagnosed as having late-onset schizophrenia (LOS) and six very-late-onset schizophrenia-like psychosis (VLOSLP). Five patients had early-onset schizophrenia and eight had delusional disorder. Females were more frequently seen in the group with LOS and the group with VLOSLP. Except for one patient with LOS, all patients with VLOSLP and LOS had paranoid psychosis. Nihilistic delusions, delusions of poverty or guilt, thought withdrawal, thought insertion, and thought broadcasting were not seen in any of the patients. Additionally, none of the LOS or VLOSLP patients showed erotomanic delusions. Grandiose and mystic delusions were not seen in those with VLOSLP. Treatment results and antipsychotic dosages at discharge were similar to those in previous reports from other cultures.

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