scholarly journals Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study

2014 ◽  
Vol 4 (6) ◽  
pp. 867-876 ◽  
Author(s):  
Andy C. Dean ◽  
Milky Kohno ◽  
Gerhard Hellemann ◽  
Edythe D. London
2017 ◽  
Vol 10 (3) ◽  
pp. 120-124 ◽  
Author(s):  
Margaret Bublitz ◽  
Suzanne De La Monte ◽  
Susan Martin ◽  
Lucia Larson ◽  
Ghada Bourjeily

Background Women with childhood maltreatment histories are at increased risk for adverse birth outcomes. Mechanisms explaining this link are poorly understood. Past research is limited by sampling pregnant women at low risk for adverse maternal and neonatal outcomes. Methods This pilot study was a secondary data analysis of 24 women with gestational diabetes mellitus; 17% of the sample also reported a maltreatment history. Women provided a blood sample to measure inflammatory cytokines and insulin resistance, and saliva samples to measure diurnal cortisol. Birth outcomes for past and current pregnancies were recorded. Results Histories of maltreatment were associated with elevated interleukin-15 and a marginally greater incidence of preterm delivery in current and past pregnancies. Conclusions This pilot study was the first to demonstrate an association between childhood maltreatment history and inflammatory cytokine levels in pregnant women diagnosed with gestational diabetes mellitus.


2015 ◽  
Vol 146 ◽  
pp. e162
Author(s):  
Milky Kohno ◽  
Andy C. Dean ◽  
Gerhard Hellemann ◽  
Edythe London

2020 ◽  
Vol 11 ◽  
Author(s):  
Nadine Bernhardt ◽  
Johannes Petzold ◽  
Cornelius Groß ◽  
Anna Scheck ◽  
Shakoor Pooseh ◽  
...  

2009 ◽  
Vol 29 (5) ◽  
pp. 488-491 ◽  
Author(s):  
Janette McGaugh ◽  
Michael J. Mancino ◽  
Zachary Feldman ◽  
Mohit P. Chopra ◽  
W. Brooks Gentry ◽  
...  

2017 ◽  
Vol 41 (S1) ◽  
pp. S152-S152
Author(s):  
E. Di Giacomo ◽  
F. Pescatore ◽  
F. Colmegna ◽  
F. Di Carlo ◽  
M. Clerici

BackgroundChildhood maltreatment is the most important risk factor for the onset of psychiatric disorders. Revictimization is really frequent as well as substance or alcohol abuse, often linked to self-treatment. Accordingly, our pilot study aims to analyze possible implication of childhood maltreatment on resilience and burnout.MethodsPatients admitted to outpatients psychiatric department in a six month period (1st January 2015–30th June 2015) complaining low to moderate anxiety or depression have been administered childhood trauma questionnaire (CTQ) and Maslach burnout inventory.ResultsCTQ results in 71 (87%) Emotional Neglect (EN), 2 (2.4%) Sexual Abuse (SA) and 2 (2.4%) Physical Abuse (PA). Twenty-one showed high emotional exhaustion, 21 high depersonalization, 9 moderate personal accomplishment while 1 showed low personal accomplishment. None of the patients who suffered child sexual abuse shows depersonalization or personal accomplishment difficulties linked to burnout. Patients negative to CTQ show respectively moderate emotional exhaustion (M = 20 ± 20.15), moderate depersonalization (11 ± 9.42) and high personal accomplishment (17 ± 12.38). Patients who suffered emotional neglect show the poorest profile at Maslach, particularly regarding emotional exhaustion. ANOVA reaches statistical significance among the 3 groups of detected abuse (EN, SA, PA) in personal accomplishment (P = 0.013) confirmed at POST HOC between EN and SA (P = 0.0004).ConclusionThe results obtained in this pilot study highlight two important considerations. First, it seems urgent to stress the huge prevalence of emotional neglect among those referred to psychiatric outpatient department due to moderate anxiety or depression complain. Moreover, emotional neglect appears to be the most compromised factor of burnout, especially if compared to sexual abuse.


2007 ◽  
Vol 39 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Charles W. Meredith ◽  
Craig Jaffe ◽  
Elisia Yanasak ◽  
Monique Cherrier ◽  
Andrew J. Saxon

2020 ◽  
Vol 32 (2) ◽  
pp. 176-185
Author(s):  
Layla Banihashemi ◽  
Meredith L. Wallace ◽  
Christine W. Peng ◽  
Mark M. Stinley ◽  
Anne Germain ◽  
...  

2016 ◽  
Vol 9 (2) ◽  
pp. 73-77 ◽  
Author(s):  
Margaret H Bublitz ◽  
Ghada Bourjeily ◽  
Chrystal Vergara-Lopez ◽  
Laura R Stroud

Background Pregnant victims of childhood maltreatment are more likely to deliver preterm. The mechanisms explaining this relationship are unclear. The goal of the current pilot study was to investigate whether momentary stress and cortisol serve as mechanisms linking maltreatment history to gestational length. Methods Seventeen women enrolled in the study (35% maltreated). Women completed two study sessions at 27 and 34 weeks gestation. Following each session, at four times/day over two days, women reported their momentary stress levels by text message and provided corresponding salivary cortisol samples. Gestational length was determined by medical chart review. Results Higher reports of momentary stress were associated with shortened gestational length. High stress predicted lower cortisol concentrations for women with maltreatment histories but higher concentrations among women without maltreatment. Conclusion Results from this pilot study provide preliminary evidence for understanding mechanisms explaining increased risk for preterm birth among childhood maltreatment victims.


Sign in / Sign up

Export Citation Format

Share Document