Phenolic Composition, Anti-Inflammatory, Antioxidant, and Antimicrobial Activities ofAlchemilla mollis(Buser)Rothm.

2017 ◽  
Vol 14 (9) ◽  
pp. e1700150 ◽  
Author(s):  
Gökçe Şeker Karatoprak ◽  
Selen İlgün ◽  
Müberra Koşar
2016 ◽  
Vol 11 (9) ◽  
pp. 1934578X1601100
Author(s):  
Yu-Chang Su ◽  
Kuan-Ping Hsu ◽  
Chen-Lung Ho

The chemical composition and in vitro anti-inflammatory, antioxidant and antimicrobial activities of the leaf essential oil of Machilus konishii has been investigated. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC–FID and GC–MS. Sixty-six compounds were identified, representing 100% of the oil. The main components identified were α-pinene (33.9%), β-pinene (13.9%), and thymol (12.0%). The leaf oil was able to reduce nitric oxide production by lipopolysaccharide-activated murine macrophages RAW 264.7 without reducing the cell viability. In addition, the leaf oil showed strong antioxidant and antimicrobial activities. The major ingredient of the oil that was responsible for the anti-inflammatory, antioxidant and antimicrobial activities was thymol.


Author(s):  
Rafaela Ribeiro Silva ◽  
Davi Oliveira e Silva ◽  
Humberto Rollemberg Fontes ◽  
Celuta Sales Alviano ◽  
Patricia Dias Fernandes ◽  
...  

2013 ◽  
Vol 5 (6) ◽  
pp. 275-280 ◽  
Author(s):  
Nassim Djabou ◽  
Mohamed El Amine Dib ◽  
Hocine Allali ◽  
Andreas Benderb ◽  
Mohammad A. Kamal ◽  
...  

2017 ◽  
Vol 55 (1) ◽  
pp. 991-997 ◽  
Author(s):  
Jhéssica Benevides Bahiense ◽  
Franciane Martins Marques ◽  
Mariana Moreira Figueira ◽  
Thais Souza Vargas ◽  
Tamara P. Kondratyuk ◽  
...  

2015 ◽  
Vol 10 (8) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Yu-Chang Su ◽  
Kuan-Ping Hsu ◽  
Kuo-Feng Hua ◽  
Chen-Lung Ho

The chemical composition and in vitro anti-inflammatory, antioxidant and antimicrobial activities of the essential oils isolated from the leaf and twig of Cupressus cashmeriana have been investigated. The essential oils were isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC–FID and GC–MS, respectively. The leaf oil mainly consisted of α-pinene (21.8%), epizonarene (8.0%), sabinene (7.9%), limonene (7.6%), γ-terpinene (7.0%), and allo-aromadendrene (7.0%); the twig oil was mostly carvacrol methyl ether (35.4%), manool (16.1%), carvacrol (14.2%), and (2 Z,6 E)-farnesol (6.9%). Twig oil, but not leaf oil, was able to reduce nitric oxide production by lipopolysaccharide-activated murine macrophages RAW 264.7 without reducing the cell viability. In addition, twig oil showed better antioxidant and antimicrobial activities than leaf oil. The major ingredient of the twig oil that was responsible for the anti-inflammatory, antioxidant and antimicrobial activities was carvacrol.


Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1907
Author(s):  
Filipa Mandim ◽  
Spyridon A. Petropoulos ◽  
Maria Inês Dias ◽  
José Pinela ◽  
Marina Kostić ◽  
...  

Hydroethanolic extracts of cardoon petioles collected at sixteen growth stages (P1–P16) were characterized in terms of their phenolic composition and bioactive potential (antioxidant, cytotoxic, anti-inflammatory, and antimicrobial activities). Fifteen phenolic compounds were tentatively identified (i.e., ten phenolic acids and five flavonoid glycosides); the main compounds were 5-O-caffeoylquinic and 1,5-di-O-caffeoylquinic acids. Samples collected at early maturity (P1–P4) presented a weak positive correlation between the higher content in polyphenols (P3: 101-mg/g extract) and better inhibition capacity against thiobarbituric acid reactive substance formation (TBARS; P3: IC50 = 5.0 µg/mL). Samples at intermediate maturation stages (P9) presented higher cytotoxic and anti-inflammatory potential. Moreover, immature petioles showed greater antihemolytic (OxHLIA; P4: IC50 = 65 and 180 µg/mL for Δt of 60 and 120 min, respectively) and antibacterial activity. The antifungal activity varied depending on the maturation stage and the fungi strain. In conclusion, the maturation stage may greatly affect the polyphenols composition and content and the bioactive potential of cardoon petioles.


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