Calcium activity in response to nAChR ligands in murine bone marrow granulocytes with different Gr‐1 expression

2021 ◽  
Author(s):  
Dmitriy Serov ◽  
Irina Tikhonova ◽  
Valentina Safronova ◽  
Maksim Astashev
Keyword(s):  
Bone Marrow ◽  
Calcium Activity ◽  
Murine Bone Marrow ◽  
Bone Marrow Granulocytes

scholarly journals Natural glucocorticoids induce expansion of all developmental stages of murine bone marrow granulocytes without inhibiting function

2008 ◽  
Vol 105 (6) ◽  
pp. 2028-2033 ◽  
Author(s):  
M. D. Trottier ◽  
M. M. Newsted ◽  
L. E. King ◽  
P. J. Fraker
Keyword(s):  
Bone Marrow ◽  
Developmental Stages ◽  
Murine Bone Marrow ◽  
Bone Marrow Granulocytes

scholarly journals Natural glucocorticoids induce survival and proliferation of murine bone marrow granulocytes without altering function

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Mark Daniel Trottier ◽  
Matthew M. Newsted ◽  
Olatundun Williams ◽  
Louis E. King ◽  
Pamela J. Fraker
Keyword(s):  
Bone Marrow ◽  
Murine Bone Marrow ◽  
Bone Marrow Granulocytes

The Influence of Exogenous ATP on Functional Responses of Murine Bone Marrow Granulocytes

2020 ◽  
Vol 14 (1) ◽  
pp. 34-43 ◽  
Author(s):  
D. A. Serov ◽  
M. E. Astashev ◽  
I. V. Tikhonova ◽  
V. G. Safronova
Keyword(s):  
Bone Marrow ◽  
Functional Responses ◽  
Murine Bone Marrow ◽  
Bone Marrow Granulocytes

W13.332 Uptake of chylomicron remnants into murine bone marrow in vivo

2004 ◽  
Vol 5 (1) ◽  
pp. 77
Author(s):  
D NIEDZIELSKA
Keyword(s):  
Bone Marrow ◽  
Murine Bone Marrow ◽  
Chylomicron Remnants

Author response for "CXCR4, but not CXCR3, drives CD8 T-cell entry into and migration through the murine bone marrow"

2018 ◽  
Author(s):  
Marieke Goedhart ◽  
Stephanie Gessel ◽  
Robbert van der Voort ◽  
Edith Slot ◽  
Beth Lucas ◽  
...  
Keyword(s):  
Bone Marrow ◽  
T Cell ◽  
Cd8 T Cell ◽  
Cell Entry ◽  
Author Response ◽  
Murine Bone Marrow ◽  
And Migration

Metaphase preparation from murine bone marrow

2008 ◽  
Author(s):  
Wei Guo ◽  
Hong Wu
Keyword(s):  
Bone Marrow ◽  
Murine Bone Marrow

scholarly journals Phagocytosis and activation of bone marrow‐derived macrophages by Plasmodium falciparum gametocytes

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Yolanda Corbett ◽  
Silvia Parapini ◽  
Federica Perego ◽  
Valeria Messina ◽  
Serena Delbue ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bone Marrow ◽  
Plasmodium Falciparum ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
Murine Bone Marrow ◽  
Inflammatory Protein ◽  
Life Cycle Stages ◽  
Cytokine Levels ◽  
Necrosis Factor

Abstract Background The innate immune response against various life cycle stages of the malaria parasite plays an important role in protection against the disease and regulation of its severity. Phagocytosis of asexual erythrocytic stages is well documented, but little and contrasting results are available about phagocytic clearance of sexual stages, the gametocytes, which are responsible for the transmission of the parasites from humans to mosquitoes. Similarly, activation of host macrophages by gametocytes has not yet been carefully addressed. Methods Phagocytosis of early or late Plasmodium falciparum gametocytes was evaluated through methanol fixed cytospin preparations of immortalized mouse C57Bl/6 bone marrow-derived macrophages treated for 2 h with P. falciparum and stained with Giemsa, and it was confirmed through a standardized bioluminescent method using the transgenic P. falciparum 3D7elo1-pfs16-CBG99 strain. Activation was evaluated by measuring nitric oxide or cytokine levels in the supernatants of immortalized mouse C57Bl/6 bone marrow-derived macrophages treated with early or late gametocytes. Results The results showed that murine bone marrow-derived macrophages can phagocytose both early and late gametocytes, but only the latter were able to induce the production of inflammatory mediators, specifically nitric oxide and the cytokines tumour necrosis factor and macrophage inflammatory protein 2. Conclusions These results support the hypothesis that developing gametocytes interact in different ways with innate immune cells of the host. Moreover, the present study proposes that early and late gametocytes act differently as targets for innate immune responses.

Postprandial triglyceride-rich lipoproteins promote lipid accumulation and apolipoprotein B-48 receptor transcriptional activity in human circulating and murine bone marrow neutrophils in a fatty acid-dependent manner

2017 ◽  
Vol 61 (9) ◽  
pp. 1600879 ◽  
Author(s):  
Almudena Ortega-Gómez ◽  
Lourdes M. Varela ◽  
Sergio López ◽  
Sergio Montserrat de la Paz ◽  
Rosario Sánchez ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Fatty Acid ◽  
Lipid Accumulation ◽  
Apolipoprotein B ◽  
Transcriptional Activity ◽  
Dependent Manner ◽  
Murine Bone Marrow ◽  
Postprandial Triglyceride
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