Highly Luminescent N-Doped Carbon Quantum Dots as an Effective Multifunctional Fluorescence Sensing Platform

A novel electrochemiluminescence sensing platform for the sensitive detection of chlorpromazine (CPZ) was fabricated based on a Ru(bpy)32+/carbon quantum dots/gelatin composite film.

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Graphitic carbon quantum dots as a fluorescent sensing platform for highly efficient detection of Fe3+ ions

RSC Advances ◽

10.1039/c3ra23410j ◽

2013 ◽

Vol 3 (11) ◽

pp. 3733 ◽

Cited By ~ 188

Author(s):

Yong-Lai Zhang ◽

Lei Wang ◽

Heng-Chao Zhang ◽

Yang Liu ◽

Hai-Yu Wang ◽

...

Keyword(s):

Quantum Dots ◽

Carbon Quantum Dots ◽

Graphitic Carbon ◽

Fluorescent Sensing ◽

Highly Efficient ◽

Efficient Detection ◽

Sensing Platform

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A fluorometric assay for tyrosinase activity and its inhibitor screening based on graphene quantum dots

RSC Advances ◽

10.1039/c6ra13325h ◽

2016 ◽

Vol 6 (76) ◽

pp. 72670-72675 ◽

Cited By ~ 23

Author(s):

X. E. Zhao ◽

C. H. Lei ◽

Y. H. Wang ◽

F. Qu ◽

S. Y. Zhu ◽

...

Keyword(s):

Quantum Dots ◽

Graphene Quantum Dots ◽

Tyrosinase Activity ◽

Fluorometric Assay ◽

Pristine Graphene ◽

Fluorescence Sensing ◽

Inhibitor Screening ◽

Sensing Platform ◽

First Time

Pristine graphene quantum dots (GQDs) without any functionalization were used as probes to develop a sensitive and selective fluorescence sensing platform for the detection of tyrosinase (TYR) activity and its inhibitor screening for the first time.

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Highly Fluorescent N-Doped Carbon Quantum Dots Derived from Bamboo Stems for Selective Detection of Fe3+ Ions in Biological Systems

Journal of Biomedical Nanotechnology ◽

10.1166/jbn.2021.3034 ◽

2021 ◽

Vol 17 (2) ◽

pp. 312-321

Author(s):

Jiamin Yan ◽

Yuneng Lu ◽

Shaowen Xie ◽

Haihu Tan ◽

Weilan Tan ◽

...

Keyword(s):

Quantum Dots ◽

Biological Systems ◽

High Sensitivity ◽

Carbon Quantum Dots ◽

Clinical Diagnostics ◽

Quenching Effect ◽

Biologically Relevant ◽

Sensing Platform ◽

Wide Ph Range ◽

High Fluorescence

The establishment of sensing platform for trace analysis of Fe3+ in biological systems is meaningful for health monitoring. Herein, a Fe3+ sensitive fluorescent nanoprobe was constructed based on highly fluorescent N-doped carbon quantum dots (NCQDs) derived from bamboo stems through a hydrothermal method employing ethylenediamine as the nitrogen dopant. The prepared NCQDs had a uniformly distributed size and their mean size was around 2.43 nm. Abundant functional groups (C=N, N-H, C=O, and carboxyl) anchored on NCQDs demonstrated successful doping of N in CQDs. The obtained NCQDs possessed a high fluorescence quantum yield of 20.02% and outstanding fluorescence stability over a wide pH range and at high ionic strengths. Moreover, Fe3+ ions presented a specific fluorescent quenching effect to the as-prepared NCQDs. The calibration curve for fluorescence quenching degree corresponding to Fe3+ concentration showed a linear response in a range of 0.01–10 µM, and detection limit was 0.486 µM, which indicated that the NCQDs had high sensitivity to Fe3+ ions. Ascribed to these unique properties, the NCQDs were selected as luminescent probes for trace amount of Fe3+ ions in human serum. These results demonstrated their promising use in clinical diagnostics and other biologically relevant studies.

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