ChemInform Abstract: SYNTHESIS AND GROWTH-PROMOTING ACTIVITY OF N(ALPHA)-ACETYL-HGH-(95-136) PART 35, HUMAN PITUITARY GROWTH HORMONE

1973 ◽  
Vol 4 (37) ◽  
pp. no-no
Author(s):  
J. BLAKE ◽  
C. H. LI
Keyword(s):  
Growth Hormone ◽  
Human Pituitary ◽  
Pituitary Growth Hormone ◽  
Growth Promoting

HUMAN PITUITARY GROWTH HORMONE VII. IN VITRO LIPOLYTIC ACTIVITY

1964 ◽  
Vol 45 (4_Suppl) ◽  
pp. S155-S162 ◽  
Author(s):  
Choh Hao Li ◽  
A. Tanaka ◽  
B. T. Pickering
Keyword(s):  
Growth Hormone ◽  
Active Sites ◽  
Lipolytic Activity ◽  
Human Growth ◽  
Intrinsic Property ◽  
Human Pituitary ◽  
Pituitary Growth Hormone ◽  
Growth Promoting ◽  
Fat Pads

ABSTRACT The in vitro lipolytic activity of human growth hormone (HGH) has been assayed on fat pads from rats, rabbits and guinea pigs. Results of various experiments suggest that lipolytic activity is an intrinsic property of HGH and that the active sites for the growth-promoting and lipolytic potencies are located in different areas of the HGH molecule.

Human Pituitary Growth Hormone, by Allen W. Root, M.D. Springfield, Illinois: Charles C Thomas, 1972, 259 pp. $10.50

PEDIATRICS ◽  
1973 ◽  
Vol 52 (1) ◽  
pp. 158-159
Author(s):  
Selna L. Kaplan
Keyword(s):  
Growth Hormone ◽  
Pituitary Gland ◽  
Control Mechanisms ◽  
Human Pituitary ◽  
Comprehensive Review ◽  
Pituitary Growth Hormone ◽  
Biochemical Effects ◽  
Clinical Syndromes

This book, divided into four sections, provides a comprehensive review of the biochemical effects of growth hormone as well as the clinical syndromes associated with abnormalities of its secretion and metabolism. The book opens with a historical résumé of the "discovery" of this hormone, identification of its varied biologic actions, and isolation from the pituitary gland. The second part discusses the development of radioimmunoassay for measurement of growth hormone by Roth and associates and the subsequent surge in studies of the control mechanisms for the secretion of growth hormone.

THE BIOASSAY OF GROWTH HORMONE IN SNELL'S DWARF MICE: EFFECTS OF THYROXINE AND PROLACTIN ON THE DOSE—RESPONSE CURVE

1973 ◽  
Vol 56 (2) ◽  
pp. 235-243 ◽  
Author(s):  
M. WALLIS ◽  
JENNIFER A. DEW
Keyword(s):  
Growth Hormone ◽  
Response Curve ◽  
Growth Response ◽  
Growth Promotion ◽  
Promoting Effect ◽  
Pituitary Growth Hormone ◽  
Growth Promoting ◽  
Dependent Growth ◽  
Dwarf Mice ◽  
Dose Dependent

SUMMARY Pituitary growth hormone has a dose-dependent growth promoting effect in pituitary dwarf mice (Snell's strain), and this effect can be used as the basis of a bioassay for the hormone. Prolactin and thyroxine also promote growth in these animals, and the effects of these hormones in combination with growth hormone were studied, in order to see whether their presence might enhance the precision or sensitivity of the growth hormone assay. When prolactin and/or thyroxine were administered with growth hormone, the growth response observed was no greater than the sum of the effects of the hormones given separately; in some cases it was less. Neither prolactin nor thyroxine increase the sensitivity or precision of the growth hormone bioassay. The implications of these results for theories about the mechanisms of growth promotion by these hormones are considered.

Human pituitary growth hormone

1975 ◽  
Vol 169 (2) ◽  
pp. 669-677 ◽  
Author(s):  
Virginia Lee ◽  
J. Ramachandran ◽  
Choh Hao Li
Keyword(s):  
Growth Hormone ◽  
Human Pituitary ◽  
Pituitary Growth Hormone

Human pituitary growth hormone

1973 ◽  
Vol 82 (1) ◽  
pp. 157
Author(s):  
Alice Baghdassarian Granoff ◽  
Myrtle Beach
Keyword(s):  
Growth Hormone ◽  
Human Pituitary ◽  
Pituitary Growth Hormone
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