Human Pituitary Growth Hormone, by Allen W. Root, M.D. Springfield, Illinois: Charles C Thomas, 1972, 259 pp. $10.50

PEDIATRICS ◽  
1973 ◽  
Vol 52 (1) ◽  
pp. 158-159
Author(s):  
Selna L. Kaplan
Keyword(s):  
Growth Hormone ◽  
Pituitary Gland ◽  
Control Mechanisms ◽  
Human Pituitary ◽  
Comprehensive Review ◽  
Pituitary Growth Hormone ◽  
Biochemical Effects ◽  
Clinical Syndromes

This book, divided into four sections, provides a comprehensive review of the biochemical effects of growth hormone as well as the clinical syndromes associated with abnormalities of its secretion and metabolism. The book opens with a historical résumé of the "discovery" of this hormone, identification of its varied biologic actions, and isolation from the pituitary gland. The second part discusses the development of radioimmunoassay for measurement of growth hormone by Roth and associates and the subsequent surge in studies of the control mechanisms for the secretion of growth hormone.

THE EXTRACTION OF PROLACTIN FROM HUMAN PITUITARY GLANDS

1965 ◽  
Vol 49 (1) ◽  
pp. 1-16 ◽  
Author(s):  
M. Apostolakis
Keyword(s):  
Growth Hormone ◽  
Pituitary Gland ◽  
List Type ◽  
Distilled Water ◽  
Hormone Activity ◽  
Isoelectric Precipitation ◽  
Human Pituitary ◽  
Pituitary Glands ◽  
Prolactin Content ◽  
The Mean

ABSTRACT A method for the extraction of prolactin from human pituitary glands is described. It is based on acetone drying, distilled water extraction, acetone and isoelectric precipitation. Two main products are obtained: Fraction R8 with a mean prolactin activity of 12.2 IU/mg and fraction U8 with a mean prolactin activity of 8.6 IU/mg. The former fraction does not contain any significant gonadotrophin activity and the latter contains on an average 50 HMG U/mg. In both cases contamination with ACTH and MSH is minimal. The growth hormone activity of both these fractions is low. It is postulated that in man too, prolactin and growth hormone are two distinct hormones. A total of 1250 human pituitary glands have been processed by this method. The mean prolactin content per pituitary gland has been found to be 73 IU.

Human pituitary growth hormone

1975 ◽  
Vol 169 (2) ◽  
pp. 669-677 ◽  
Author(s):  
Virginia Lee ◽  
J. Ramachandran ◽  
Choh Hao Li
Keyword(s):  
Growth Hormone ◽  
Human Pituitary ◽  
Pituitary Growth Hormone

Human pituitary growth hormone

1973 ◽  
Vol 82 (1) ◽  
pp. 157
Author(s):  
Alice Baghdassarian Granoff ◽  
Myrtle Beach
Keyword(s):  
Growth Hormone ◽  
Human Pituitary ◽  
Pituitary Growth Hormone
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