ChemInform Abstract: AMINO ACIDS AND PEPTIDES. CLVIX. 1-(β-MERCAPTOPROPIONIC ACID)-8-(α-AMINO-β-(GLYCYLAMINO)PROPIONIC ACID)VASOPRESSIN, A VASOPRESSIN ANALOG WITH AN ISOPEPTIDE STRUCTURE IN ITS MOLECULE

SummaryChanges in distribution of amino acid nitrogen of chopped wheat plants ensiled at shooting and flowering when wilted, and at the milk and dough stages as fresh material, were determined as affected by addition of 0·8% propionic acid (PrA) or 2·2% urea phosphate-calcium propionate (UP-CaPr). Analyses were carried out after an ensiling period of 90 days and after a further aerobic exposure period (AE) of 7 days.Total amino acid (TAA) contents in the dry matter (D.M.) during the fermentation period and in the AE were stable in untreated material (UM) and treated material. Concentration of essential amino acids decreased during fermentation, this decrease being higher in the UM. The free amino acids were low in the fresh material (18·6% of TAA) but increased in the ensiled material to ca. 71 % of the TAA in the silage. In the AE this level was 63% in UM and 69% in treated material. The ammonia-N contents increased during fermentation in UM and especially in the UP-CaPr treatments, while the opposite occurred in the PrA treatments.The concentrations of and changes in 21 amino acids (AAs) are given. The highest AA concentrations recorded in the fresh material were those of arginine, lysine, glutamic acid, alanine, leucine, proline and glycine. The most marked increments in AAs as a result of fermentation were those of ornithine, γ-amino butyric acid, threonine and methionine. Marked decreases were observed in glutamine, arginine and glutamic acid. PrA increased mainly arginine, asparagine and glutamine, whereas γ-amino butyric acid decreased; UP-CaPr increased arginine, asparagine, lysine and glutamic acid (in silage only) and reduced γ-amino butyric acid and glutamine (in AE only).

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Characteristics and stability of the OPA/3-mercaptopropionic acid and OPA/N-acetyl-L-cysteine derivatives of amino acids

Chromatographia ◽

10.1007/bf02490327 ◽

2001 ◽

Vol 53 (S1) ◽

pp. S188-S198 ◽

Cited By ~ 21

Author(s):

D. Kutlán ◽

I. Molnár-Perl

Keyword(s):

Amino Acids ◽

Mercaptopropionic Acid ◽

Derivatives Of

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Thiyl radicals. III. Some reactions of anthracene, 1,2-benzanthracene, and 3,4-benzopyrene with thiols and oxygen

Australian Journal of Chemistry ◽

10.1071/ch9640109 ◽

1964 ◽

Vol 17 (1) ◽

pp. 109 ◽

Cited By ~ 3

Author(s):

ALJ Beckwith ◽

LB See

Keyword(s):

Propionic Acid ◽

Alkaline Hydrolysis ◽

Room Temperature ◽

Zinc Powder ◽

Thioacetic Acid ◽

Mercaptopropionic Acid ◽

Thiyl Radicals

Anthracene, 3-mercaptopropionic acid, and oxygen interact in benzene at room temperature yielding 3-(9-anthry1thio)propionic acid (IV), from which anthracene is regenerated by alkaline hydrolysis in the presence of zinc powder. S-(9-anthryl)-N-acetyl-L-cysteine (VI) was similarly formed from anthracene, oxygen, and N-acetyl-L-cysteine, but experiments using L-cysteine were unsuccessful. Although 1-butanethiol and methyl mercaptoacetate each react readily with anthracene and oxygen, pure products could not be isolated. Thioacetic acid and oxygen react with l,2-benzanthracene yielding 10-acetylthio-l,2-benzanthracene (IX) and 9,10-di(acetylthio)-9,10-dihydro-1,2-benzanthracene (X). 3,4-Benzopyrene, when similarly treated, affords 5-acetyl-thio-3,4-benzopyrene (XI) but phenanthrene, pyrene, perylene, and 1,2:5,6-dibenzanthracene remain unaffected. The theoretical and biochemical implications of these results are discussed.

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Dietary supplementation of propionylated starch to domestic cats provides propionic acid as gluconeogenic substrate potentially sparing the amino acid valine

Journal of Nutritional Science ◽

10.1017/jns.2014.18 ◽

2014 ◽

Vol 3 ◽

Cited By ~ 4

Author(s):

Kristel Rochus ◽

An Cools ◽

Geert P. J. Janssens ◽

Lynn Vanhaecke ◽

Birgitte Wuyts ◽

...

Keyword(s):

Amino Acids ◽

Amino Acid ◽

Propionic Acid ◽

Protein Intake ◽

Protein Digestibility ◽

Domestic Cats ◽

Intake Level ◽

Health And Disease ◽

And Control ◽

Gluconeogenic Substrate

AbstractIn strict carnivorous domestic cats, a metabolic competition arises between the need to use amino acids for gluconeogenesis and for protein synthesis both in health and disease. The present study investigated the amino acid-sparing potential of propionic acid in cats using dietary propionylated starch (HAMSP) supplementation. A total of thirty cats were fed a homemade diet, supplemented with either HAMSP, acetylated starch (HAMSA) or celite (Control) for three adaptation weeks. Propionylated starch was hypothesised to provide propionic acid as an alternative gluconeogenic substrate to amino acids, whereas acetic acid from HAMSA would not provide any gluconeogenic benefit. Post-adaptation, a 5-d total faecal collection was carried out to calculate apparent protein digestibility coefficients. Fresh faecal and blood samples were collected to analyse fermentation endproducts and metabolites. The apparent protein digestibility coefficients did not differ between supplements (P = 0·372) and were not affected by the protein intake level (P = 0·808). Faecal propionic acid concentrations were higher in HAMSP than in HAMSA (P = 0·018) and Control (P = 0·003) groups, whereas concentrations of ammonia (P = 0·007) were higher in HAMSA than in HAMSP cats. Tendencies for or higher propionylcarnitine concentrations were observed in HAMSP compared with HAMSA (P = 0·090) and Control (P = 0·037) groups, and for tiglyl- + 3-methylcrotonylcarnitine concentrations in HAMSP as compared with Control (P = 0·028) cats. Methylmalonylcarnitine concentrations did not differ between groups (P = 0·740), but were negatively correlated with the protein intake level (r –0·459, P = 0·016). These results suggest that HAMSP cats showed more saccharolytic fermentation patterns than those supplemented with HAMSA, as well as signs of sparing of valine in cats with a sufficient protein intake.

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