ChemInform Abstract: Recent Advances in Synthetic Method of Nitrogen Heterocycles via Aza- Wittig Reaction

ChemInform ◽  
2010 ◽  
Vol 24 (42) ◽  
pp. no-no
Author(s):  
S. EGUCHI ◽  
T. OKANO
Keyword(s):  
Wittig Reaction ◽  
Nitrogen Heterocycles ◽  
Synthetic Method ◽  
Recent Advances

scholarly journals Recent Advances in the Application of Ring-Closing Metathesis for the Synthesis of Unsaturated Nitrogen Heterocycles

Synthesis ◽  
2019 ◽  
Vol 51 (05) ◽  
pp. 1100-1114 ◽  
Author(s):  
Emilia Groso ◽  
Corinna Schindler
Keyword(s):  
Olefin Metathesis ◽  
Nitrogen Heterocycles ◽  
Short Review ◽  
Catalyst Design ◽  
Carbene Ligands ◽  
Ring Closing Metathesis ◽  
Recent Advances ◽  
Metathesis Reactions

This short review summarizes recent advances relating to the application of ring-closing olefin-olefin and carbonyl-olefin metathesis reactions towards the synthesis of unsaturated five- and six-membered nitrogen heterocycles. These developments include catalyst modifications and reaction designs that will enable access to more complex nitrogen heterocycles.1 Introduction2 Expansion of Ring-Closing Metathesis Methods3 Evaluation of Catalyst Design4 Indenylidene Catalysts5 Unsymmetrical N-Heterocyclic Carbene Ligands6 Carbonyl-Olefin Metathesis7 Conclusions

Recent Advances in the Synthesis of Nitrogen Heterocycles Using Arenediazonium Salts as Nitrogen Sources

2020 ◽  
Vol 362 (22) ◽  
pp. 4876-4895 ◽  
Author(s):  
Jidan Liu ◽  
Jinyuan Jiang ◽  
Liyao Zheng ◽  
Zhao‐Qing Liu
Keyword(s):  
Nitrogen Heterocycles ◽  
Nitrogen Sources ◽  
Recent Advances ◽  
Arenediazonium Salts

Recent advances in the synthesis of nitrogen heterocycles via radical cascade reactions using isonitriles as radical acceptors

2015 ◽  
Vol 44 (11) ◽  
pp. 3505-3521 ◽  
Author(s):  
Bo Zhang ◽  
Armido Studer
Keyword(s):  
Nitrogen Heterocycles ◽  
Cascade Reactions ◽  
Insertion Reactions ◽  
Recent Advances ◽  
Radical Cascade

Radical isonitrile insertion reactions are highly valuable for the construction of N-containing heterocycles such as phenanthridines, quinolines, isoquinolines, quinoxalines and indoles.

Recent Advances in the Synthesis of Heterocycles by the Aza-Wittig Reaction

Synthesis ◽  
2021 ◽  
Author(s):  
Mohammad Mahdavi ◽  
Keyvan Pedrood ◽  
Mohammad Nazari Montazer ◽  
Bagher Larijani
Keyword(s):  
Heterocyclic Compounds ◽  
Wittig Reaction ◽  
Recent Advances ◽  
Wide Range ◽  
Wittig Reactions

AbstractThe formation of the C=N bond in recent studies on heterocyclic compounds via the aza-Wittig reaction is reviewed. Furthermore, two different strategies for the formation of heterocyclic compounds, including intermolecular and intramolecular aza-Wittig reactions are described. The primary aim of this review is to provide up-to-date information on the application of the aza-Wittig reaction in the synthesis of a wide range of N-containing heterocyclic compounds in the chemical literature since 2010.1 Introduction2 Mechanism of the Staudinger and Aza-Wittig Reactions3 Intramolecular Aza-Wittig Reaction4 Intermolecular Aza-Wittig Reaction5 Conclusion

scholarly journals Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling

2019 ◽  
Vol 91 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Lars Longwitz ◽  
Thomas Werner
Keyword(s):  
Driving Force ◽  
Wittig Reaction ◽  
Redox Cycling ◽  
Organic Transformations ◽  
Microwave Assisted ◽  
Recent Advances ◽  
Thermodynamic Driving Force ◽  
Wittig Reactions ◽  
By Products

Abstract Numerous organic transformations are based on the use of stoichiometric amounts of phosphorus reagents. The formation of phosphane oxides from phosphanes is usually the thermodynamic driving force for these reactions. The stoichiometric amounts of phosphane oxide which are formed as by-products often significantly hamper the product purification. Organophosphorus catalysis based on P(III)/P(V) redox cycling aims to address these problems. Herein we present our recent advances in developing catalytic Wittig-type reactions. More specifically, we reported our results on catalytic Wittig reactions based on readily available Bu3P=O as pre-catalyst as well as the first microwave-assisted version of this reaction and the first enantioselective catalytic Wittig reaction utilizing chiral phosphane catalysts. Further developments led to the implementation of catalytic base-free Wittig reactions yielding highly functionalized alkylidene and arylidene succinates.

scholarly journals Recent advances in the synthesis of bridgehead (or ring-junction) nitrogen heterocycles via transition metal-catalyzed C–H bond activation and functionalization

2020 ◽  
Vol 7 (19) ◽  
pp. 3067-3099
Author(s):  
Biao Nie ◽  
Wanqing Wu ◽  
Yingjun Zhang ◽  
Huanfeng Jiang ◽  
Ji Zhang
Keyword(s):  
Transition Metal ◽  
Bond Activation ◽  
Nitrogen Heterocycles ◽  
Fused Heterocycles ◽  
Recent Advances ◽  
Ring Junction ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Bridgehead Nitrogen

An update on recent advances in the synthesis of bridgehead nitrogen fused heterocycles via transition metal-catalyzed C–H activation and functionalization is reported.

Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions

2019 ◽  
Vol 17 (15) ◽  
pp. 3670-3708 ◽  
Author(s):  
Maxim G. Vinogradov ◽  
Olga V. Turova ◽  
Sergei G. Zlotin
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Reaction ◽  
Nitrogen Heterocycles ◽  
Michael Reactions ◽  
Naturally Occurring ◽  
Recent Advances

In this review, recent applications of a stereoselective aza-Michael reaction for asymmetric synthesis of naturally occurring N-containing heterocyclic scaffolds and their usefulness to pharmacology are summarized.

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