ChemInform Abstract: Protein Structure-Based Design, Synthesis, and Biological Evaluation of 5-Thia-2,6-diamino-4(3H)-oxopyrimidines: Potent Inhibitors of Glycinamide Ribonucleotide Transformylase with Potent Cell Growth Inhibition.

ChemInform ◽  
2010 ◽  
Vol 28 (48) ◽  
pp. no-no ◽  
Author(s):  
M. D. VARNEY ◽  
C. L. PALMER ◽  
W. H. III ROMINES ◽  
T. BORITZKI ◽  
S. A. MARGOSIAK ◽  
...  
Keyword(s):  
Protein Structure ◽  
Cell Growth ◽  
Growth Inhibition ◽  
Biological Evaluation ◽  
Cell Growth Inhibition ◽  
Design Synthesis ◽  
Glycinamide Ribonucleotide Transformylase ◽  
Synthesis And Biological Evaluation

Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: Cancer cell growth inhibition, ROS production and hemolytic activity

2011 ◽  
Vol 46 (9) ◽  
pp. 3778-3787 ◽  
Author(s):  
Alane Cabral de Oliveira ◽  
Elizabeth A. Hillard ◽  
Pascal Pigeon ◽  
Danilo Damasceno Rocha ◽  
Felipe A.R. Rodrigues ◽  
...  
Keyword(s):  
Cell Growth ◽  
Growth Inhibition ◽  
Cancer Cell ◽  
Hemolytic Activity ◽  
Biological Evaluation ◽  
Ros Production ◽  
Cell Growth Inhibition ◽  
Cancer Cell Growth ◽  
Tetrasubstituted Olefins

Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD–paclitaxel conjugates for integrin-assisted drug delivery

2015 ◽  
Vol 13 (27) ◽  
pp. 7530-7541 ◽  
Author(s):  
A. Bianchi ◽  
D. Arosio ◽  
P. Perego ◽  
M. De Cesare ◽  
N. Carenini ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tumor Growth ◽  
Growth Inhibition ◽  
Biological Evaluation ◽  
Tumor Growth Inhibition ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Novel RGD–PTX multivalent conjugates, presenting enhanced binding for an αvβ3 integrin, have been reported. In vivo evaluation of 3b showed tumor growth inhibition through administering one-third of the PTX dose.

ChemInform Abstract: Novel Acridinedione Derivatives: Design, Synthesis, SIRT1 Enzyme and Tumor Cell Growth Inhibition Studies.

ChemInform ◽  
2012 ◽  
Vol 43 (38) ◽  
pp. no-no
Author(s):  
Mallika Alvala ◽  
Shubhmita Bhatnagar ◽  
Alvala Ravi ◽  
Variam Ullas Jeankumar ◽  
Thimmappa H. Manjashetty ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Growth Inhibition ◽  
Tumor Cell Growth ◽  
Cell Growth Inhibition ◽  
Design Synthesis ◽  
Inhibition Studies

Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies

2012 ◽  
Vol 22 (9) ◽  
pp. 3256-3260 ◽  
Author(s):  
Mallika Alvala ◽  
Shubhmita Bhatnagar ◽  
Alvala Ravi ◽  
Variam Ullas Jeankumar ◽  
Thimmappa H Manjashetty ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Growth Inhibition ◽  
Tumor Cell Growth ◽  
Cell Growth Inhibition ◽  
Design Synthesis ◽  
Inhibition Studies
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