ChemInform Abstract: Peptidomimetics for Bridging Structure and Function: Pseudoprolines (Ψ-Pro) in Peptide Synthesis, Molecular Recognition, and Drug Design

ChemInform ◽  
2010 ◽  
Vol 32 (42) ◽  
pp. no-no
Author(s):  
Gabriele Tuchscherer ◽  
Manfred Mutter
Keyword(s):  
Molecular Recognition ◽  
Drug Design ◽  
Peptide Synthesis ◽  
Structure And Function ◽  
And Function

Supramolecular DNA nanotechnology

2009 ◽  
Vol 81 (12) ◽  
pp. 2157-2181 ◽  
Author(s):  
Faisal A. Aldaye ◽  
Hanadi F. Sleiman
Keyword(s):  
Molecular Recognition ◽  
Base Pair ◽  
Deoxyribonucleic Acid ◽  
Materials Science ◽  
Dna Nanotechnology ◽  
Structure And Function ◽  
Fine Tuning ◽  
Functional Potential ◽  
And Function ◽  
Main Material

Nature uses deoxyribonucleic acid (DNA) as the main material for the storage and transmission of life’s blueprint. Today, DNA is being used as a “smart” material to help solve a number of long-standing issues facing researchers in materials science and nanotechnology. In DNA nanotechnology, DNA’s powerful base-pair molecular recognition criteria are utilized to control the final structure and function of the material being generated. A sub-area of research that our group has recently termed “supramolecular DNA nanotechnology” is emerging and is extending the limits of this molecule in nanotechnology by further fine-tuning DNA’s structural and functional potential. This review will discuss the fruition and fundamentals of supramolecular DNA nanotechnology, as well as its future as a viable science in a material world.

Probing the Structure and Function of Human Glutaminase-Interacting Protein: A Possible Target for Drug Design†‡

Biochemistry ◽  
2008 ◽  
Vol 47 (35) ◽  
pp. 9208-9219 ◽  
Author(s):  
Monimoy Banerjee ◽  
Chengdong Huang ◽  
Javier Marquez ◽  
Smita Mohanty
Keyword(s):  
Drug Design ◽  
Protein A ◽  
Structure And Function ◽  
Interacting Protein ◽  
And Function

scholarly journals Structure and function of Zika virus NS5 protein: perspectives for drug design

2018 ◽  
Vol 75 (10) ◽  
pp. 1723-1736 ◽  
Author(s):  
Boxiao Wang ◽  
Stephanie Thurmond ◽  
Rong Hai ◽  
Jikui Song
Keyword(s):  
Drug Design ◽  
Zika Virus ◽  
Structure And Function ◽  
And Function

The current status of antiparasite chemotherapy

Parasitology ◽  
1997 ◽  
Vol 114 (7) ◽  
pp. 3-15 ◽  
Author(s):  
S. L. CROFT
Keyword(s):  
Drug Discovery ◽  
Drug Design ◽  
Sesquiterpene Lactones ◽  
Molecular Targets ◽  
Structure And Function ◽  
Current Status ◽  
Rational Approach ◽  
Pharmacological Properties ◽  
Antiparasitic Drugs ◽  
And Function

Currently used antiparasitic drugs, including benzimidazoles, nitroimidazoles, avermectins, polyene ionophores, hydroxynaphthoquinones and sesquiterpene lactones, were identified through the empirical route to drug discovery. The modern rational approach to drug design is focused upon the structure and function of biochemical and molecular targets. The requisite pharmacological properties for new anti-parasite drugs should not be ignored in this process.

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