Evaluation of the Edman degradation product of vancomycin bonded to core-shell particles as a new HPLC chiral stationary phase

Chirality ◽  
2018 ◽  
Vol 30 (9) ◽  
pp. 1067-1078 ◽  
Author(s):  
Garrett Hellinghausen ◽  
Diego A. Lopez ◽  
Jauh T. Lee ◽  
Yadi Wang ◽  
Choyce A. Weatherly ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Degradation Product ◽  
Chiral Stationary Phase ◽  
Core Shell ◽  
Edman Degradation ◽  
Shell Particles

Performance Comparison Between Monolithic, Core-Shell, and Totally Porous Particulate Columns for Application in Greener and Faster Chromatography

2018 ◽  
Vol 101 (6) ◽  
pp. 1985-1992 ◽  
Author(s):  
Adel Ehab Ibrahim ◽  
Hisham Hashem ◽  
Hanaa Saleh ◽  
Magda Elhenawee
Keyword(s):  
Stationary Phase ◽  
Mobile Phase ◽  
Separation Efficiency ◽  
Stationary Phases ◽  
Shape Selectivity ◽  
Performance Comparison ◽  
Core Shell ◽  
Porous Particles ◽  
Shell Particles ◽  
Theoretical Plates

Abstract Background: The introduction of monolithic rods and core-shell particles as new morphologies of packing materials different from the conventional totally porous particles resulted in a leap forward for performance in LC. Meanwhile, environmental safety has become increasingly important in many areas, especially in industry and research laboratories. Objective: This study compared the efficiencies of commercially available columns of different lengths and diameters when greener chromatographic conditions were utilized. The main purpose of this study is to help practitioners select the most appropriate stationary phase for faster and greener analysis. Methods: The three types of stationary phases were compared in terms of separation efficiency, number of theoretical plates, peak shape, selectivity, resolution, analysis time, mobile phase consideration, and permeability using six drug molecules. Results: Results indicated that core-shell and monolithic stationary phases had superiority over the conventional totally porous particles in terms of efficiency and speed of analysis. Monolithic rods had lower column backpressure and higher permeability, so they are more suitable for higher mobile phase flow rates and viscosities. However, core-shell particles provided enhanced peak shapes and number of theoretical plates. Conclusions: The choice will depend on the main purpose of analysis and the composition of the mobile phase. Compromise must be made to obtain the best trade-off between separation efficiency and analysis speed. Highlights: This study is the first to consider green chromatography concepts for the selection of the best stationary phase of new morphologies.

Pirkle-type chiral stationary phase on core–shell and fully porous particles: Are superficially porous particles always the better choice toward ultrafast high-performance enantioseparations?

2016 ◽  
Vol 1466 ◽  
pp. 96-104 ◽  
Author(s):  
Omar H. Ismail ◽  
Luisa Pasti ◽  
Alessia Ciogli ◽  
Claudio Villani ◽  
Jelena Kocergin ◽  
...  
Keyword(s):  
Stationary Phase ◽  
High Performance ◽  
Chiral Stationary Phase ◽  
Core Shell ◽  
Porous Particles ◽  
Superficially Porous Particles

scholarly journals Nanocellulose Derivative/Silica Hybrid Core-Shell Chiral Stationary Phase: Preparation and Enantioseparation Performance

Molecules ◽  
2016 ◽  
Vol 21 (5) ◽  
pp. 561 ◽  
Author(s):  
Xiaoli Zhang ◽  
Litao Wang ◽  
Shuqing Dong ◽  
Xia Zhang ◽  
Qi Wu ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Core Shell ◽  
Silica Hybrid

Magnetic Properties of Fe3O4/CoFe2O4 Composite Nanoparticles with Core/Shell Architecture

2020 ◽  
Vol 65 (10) ◽  
pp. 904
Author(s):  
V. O. Zamorskyi ◽  
Ya. M. Lytvynenko ◽  
A. M. Pogorily ◽  
A. I. Tovstolytkin ◽  
S. O. Solopan ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Spinel Ferrite ◽  
Composite Nanoparticles ◽  
Core Shell ◽  
Cofe2o4 Nanoparticles ◽  
Core Diameter ◽  
The Core ◽  
Shell Particles ◽  
Interface Parameters ◽  
Shell Composite

Magnetic properties of the sets of Fe3O4(core)/CoFe2O4(shell) composite nanoparticles with a core diameter of about 6.3 nm and various shell thicknesses (0, 1.0, and 2.5 nm), as well as the mixtures of Fe3O4 and CoFe2O4 nanoparticles taken in the ratios corresponding to the core/shell material contents in the former case, have been studied. The results of magnetic research showed that the coating of magnetic nanoparticles with a shell gives rise to the appearance of two simultaneous effects: the modification of the core/shell interface parameters and the parameter change in both the nanoparticle’s core and shell themselves. As a result, the core/shell particles acquire new characteristics that are inherent neither to Fe3O4 nor to CoFe2O4. The obtained results open the way to the optimization and adaptation of the parameters of the core/shell spinel-ferrite-based nanoparticles for their application in various technological and biomedical domains.

Chiral drugs separation by a new antibiotics-based chiral stationary phase

2014 ◽  
Author(s):  
Chunye Liu ◽  
Yanqing Miao ◽  
Yihui Guo ◽  
Yinjuan An ◽  
Yunfang Li ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Chiral Drugs ◽  
New Antibiotics

Advances in polymer materials as chiral stationary phase

2016 ◽  
Vol 34 (1) ◽  
pp. 34 ◽  
Author(s):  
Rongji DAI ◽  
Huiting WANG ◽  
Weiwei SUN ◽  
Yulin DENG ◽  
Fang LV ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Polymer Materials

A Novel Approach for the Preparation of Core-Shell MOF/polymer Composites as Mixed-Mode Stationary Phase

Talanta ◽  
2021 ◽  
pp. 122459
Author(s):  
Tiantian Si ◽  
Licheng Wang ◽  
Xiaojing Liang ◽  
Xiaofeng Lu ◽  
Shuai Wang ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Polymer Composites ◽  
Mixed Mode ◽  
Core Shell ◽  
Novel Approach
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