Model-Based Optimal Design of Continuous-Flow Reactors for the Synthesis of Active Pharmaceutical Ingredients

2016 ◽  
Vol 88 (9) ◽  
pp. 1215-1216 ◽  
Author(s):  
V. N. Emenike ◽  
U. Krewer
Keyword(s):  
Optimal Design ◽  
Continuous Flow ◽  
Active Pharmaceutical Ingredients ◽  
Flow Reactors ◽  
Pharmaceutical Ingredients ◽  
Model Based ◽  
Continuous Flow Reactors

scholarly journals Online model-based redesign of experiments for improving parameter precision in continuous flow reactors

2018 ◽  
Vol 51 (15) ◽  
pp. 359-364
Author(s):  
Arun Pankajakshan ◽  
Marco Quaglio ◽  
Conor Waldron ◽  
Enhong Cao ◽  
Asterios Gavriilidis ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Reactors ◽  
Model Based ◽  
Parameter Precision ◽  
Continuous Flow Reactors

Continuous flow reactors: a perspective

2012 ◽  
Vol 14 (1) ◽  
pp. 38-54 ◽  
Author(s):  
Charlotte Wiles ◽  
Paul Watts
Keyword(s):  
Continuous Flow ◽  
Flow Reactors ◽  
Continuous Flow Reactors

Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients

2022 ◽  
Author(s):  
Cloudius Sagandira ◽  
Sinazo Nqeketo ◽  
Kanysile Mhlana ◽  
Thembela Sonti ◽  
Paul Watts ◽  
...  
Keyword(s):  
Pharmaceutical Industry ◽  
Continuous Flow ◽  
Industrial Revolution ◽  
Flow Chemistry ◽  
Active Pharmaceutical Ingredients ◽  
New Paradigm ◽  
Pharmaceutical Ingredients ◽  
Continuous Flow Chemistry

Continuous flow chemistry has opened a new paradigm in both the laboratory and pharmaceutical industry. This review details the recently reported literature on continuous multistep telescoped synthesis of active pharmaceutical...

Synthesis of Tailored Segmented Polyurethanes Utilizing Continuous-Flow Reactors and Real-Time Process Monitoring

2021 ◽  
Author(s):  
Xabier Lopez de Pariza ◽  
Tim Erdmann ◽  
Pedro L. Arrechea ◽  
Leron Perez ◽  
Charles Dausse ◽  
...  
Keyword(s):  
Real Time ◽  
Process Monitoring ◽  
Continuous Flow ◽  
Time Process ◽  
Flow Reactors ◽  
Segmented Polyurethanes ◽  
Continuous Flow Reactors

Functional Group Interconversion Reactions in Continuous Flow Reactors

2021 ◽  
Vol 25 ◽  
Author(s):  
Alexander Leslie ◽  
Angel Maria Joseph ◽  
Marcus Baumann
Keyword(s):  
Continuous Flow ◽  
Functional Group ◽  
Modern Synthesis ◽  
Flow Reactors ◽  
Flow Synthesis ◽  
Specific Reaction ◽  
Solid Foundation ◽  
Continuous Flow Reactors ◽  
Flow Techniques

: An overview of the current uptake of continuous flow techniques for various functional group interconversion reactions is presented. Besides highlighting a variety of prominent examples and their main features, this review provides insights into specific reaction classes, such as oxidations, reductions, rearrangements as well as different C-H functionalization processes. While this review can only include key examples from the last decade, the reader will find a solid foundation of important transformations along with further references to inform and appreciate the opportunities arising from modern synthesis technologies such as flow synthesis.

Visible light-induced iniferter polymerization of methacrylates enhanced by continuous flow

2017 ◽  
Vol 8 (42) ◽  
pp. 6496-6505 ◽  
Author(s):  
Maarten Rubens ◽  
Phanumat Latsrisaeng ◽  
Tanja Junkers
Keyword(s):  
Block Copolymers ◽  
Visible Light ◽  
Continuous Flow ◽  
Flow Reactors ◽  
Continuous Flow Reactors

Visible-light induced photoiniferter polymerization in continuous flow reactors is very efficient in yielding low dispersity methacrylate block copolymers.

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